<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0202</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2007-05-11</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001066833</issuerCik>
        <issuerName>DOV PHARMACEUTICAL INC</issuerName>
        <issuerTradingSymbol>DOVP</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001278736</rptOwnerCik>
            <rptOwnerName>POLYGON GLOBAL OPPORTUNITIES MASTER FUND</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001308513</rptOwnerCik>
            <rptOwnerName>Polygon Investment Partners LLP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001308514</rptOwnerCik>
            <rptOwnerName>Polygon Investment Partners LP</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001388444</rptOwnerCik>
            <rptOwnerName>Polygon Investment Partners HK LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001308098</rptOwnerCik>
            <rptOwnerName>Polygon Investments Ltd.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001400002</rptOwnerCik>
            <rptOwnerName>Polygon Investment Management LTD</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001400001</rptOwnerCik>
            <rptOwnerName>Polygon Investment Partners GP, LLC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001399998</rptOwnerCik>
            <rptOwnerName>Reade E. Griffith</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001399994</rptOwnerCik>
            <rptOwnerName>Alexander E. Jackson</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001399996</rptOwnerCik>
            <rptOwnerName>Patrick G. G. Dear</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O POLYGON INVESTMENT PARTNERS LLP</rptOwnerStreet1>
            <rptOwnerStreet2>10 DUKE OF YORK SQUARE</rptOwnerStreet2>
            <rptOwnerCity>LONDON SW3 4LY UNITED KINGDOM</rptOwnerCity>
            <rptOwnerState></rptOwnerState>
            <rptOwnerZipCode></rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <derivativeTable>
        <derivativeHolding>
            <securityTitle>
                <value>Series C Convertible Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F1"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F1"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F1"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>12225672</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
        <derivativeHolding>
            <securityTitle>
                <value>Series D Convertible Preferred Stock</value>
            </securityTitle>
            <conversionOrExercisePrice>
                <footnoteId id="F2"/>
            </conversionOrExercisePrice>
            <exerciseDate>
                <footnoteId id="F2"/>
            </exerciseDate>
            <expirationDate>
                <footnoteId id="F2"/>
            </expirationDate>
            <underlyingSecurity>
                <underlyingSecurityTitle>
                    <value>Common Stock</value>
                </underlyingSecurityTitle>
                <underlyingSecurityShares>
                    <value>19102612</value>
                </underlyingSecurityShares>
            </underlyingSecurity>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </derivativeHolding>
    </derivativeTable>

    <footnotes>
        <footnote id="F1">The Series C Convertible Preferred Stock is convertible into common stock at any time, at the holders' election, between May 11, 2007 and June 10, 2007 at a conversion rate of 191.02612143 shares of common stock for one share of Series C Convertible Preferred Stock.  All shares of Series C Convertible Preferred Stock not converted on June 10, 2007 shall be automatically converted to common stock.</footnote>
        <footnote id="F2">The Series D Convertible Preferred Stock is convertible into common stock at any time after May 11, 2007, to the extent that the Reporting Persons would not beneficially own shares of capital stock having in excess of 9.99% of the voting power of Dov immediately after giving effect to such conversion.   The Series D Convertible Preferred Stock has no expiration date and is convertible into common stock at a conversion rate of 191.02612143 shares of common stock for one share of Series D Convertible Preferred Stock.</footnote>
    </footnotes>

    <remarks>This Form 3 is filed on behalf of Polygon Global Opportunities Master Fund, Polygon Investments Ltd., Polygon Investment Management Limited, Polygon Investment Partners LLP, Polygon Investment Partners LP, Polygon Investment Partners HK Limited, Polygon Investment Partners GP, LLC, Mr. Reade E. Griffith, Mr. Alexander E. Jackson and Mr. Patrick G. G. Dear.</remarks>

    <ownerSignature>
        <signatureName>POLYGON GLOBAL OPPORTUNITIES MASTER FUND By: Polygon Investment Partners LLP, its investment manager By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENT MANAGEMENT LIMITED By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENTS LTD. By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENT PARTNERS LLP By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENT PARTNERS LP By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENT PARTNERS HK LIMITED By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>POLYGON INVESTMENT PARTNERS GP, LLC By: /s/ Patrick G. G. Dear, Principal</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Reade E. Griffith</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Alexander E. Jackson</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>

    <ownerSignature>
        <signatureName>/s/ Patrick G G. Dear</signatureName>
        <signatureDate>2007-05-21</signatureDate>
    </ownerSignature>
</ownershipDocument>
