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The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP FIGI (to the nearest dollar) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ACADIA PHARMACEUTICALS INC COM 004225108   50,136,726 2,405,793 SH   SOLE   2,405,793 0 0
ALDEYRA THERAPEUTICS INC COM 01438T106   1,074,144 160,800 SH   SOLE   160,800 0 0
ALIGN TECHNOLOGY INC COM 016255101   17,007,851 55,705 SH   SOLE   55,705 0 0
ALKERMES PLC COM G01767105   16,901,234 603,400 SH   SOLE   603,400 0 0
AMICUS THERAPEUTICS INC COM 03152W109   127,972,108 10,524,022 SH   SOLE   10,524,022 0 0
ANAPTYSBIO INC COM 032724106   7,744,783 431,224 SH   SOLE   431,224 0 0
BIOGEN INC COM 09062X103   97,993,287 381,282 SH   SOLE   381,282 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101   162,009,977 1,831,035 SH   SOLE   1,831,035 0 0
CYTOKINETICS INC COM 23282W605   3,291,183 111,717 SH   SOLE   111,717 0 0
EHEALTH INC COM 28238P109   20,271,405 2,739,379 SH   SOLE   2,739,379 0 0
GOSSAMER BIO INC COM 38341P102   5,438,424 6,530,288 SH   SOLE   6,530,288 0 0
INSMED INC COM 457669307   148,709,648 5,889,491 SH   SOLE   5,889,491 0 0
KARYOPHARM THERAPEUTICS INC COM 48576U106   7,605,674 5,675,876 SH   SOLE   5,675,876 0 0
KEZAR LIFE SCIENCES INC COM 49372L100   780,878 656,200 SH   SOLE   656,200 0 0
MIRUM PHARMACEUTICALS INC COM 604749101   2,044,520 64,700 SH   SOLE   64,700 0 0
NEVRO CORP COM 64157F103   7,434,911 386,832 SH   SOLE   386,832 0 0
NOVOCURE LTD COM G6674U108   10,663,441 660,275 SH   SOLE   660,275 0 0
PROTHENA CORP PLC COM G72800108   79,972,349 1,657,458 SH   SOLE   1,657,458 0 0
RELMADA THERAPEUTICS INC COM 75955J402   2,197,200 732,400 SH   SOLE   732,400 0 0
REVANCE THERAPEUTICS INC COM 761330109   59,972,145 5,228,609 SH   SOLE   5,228,609 0 0
SAGE THERAPEUTICS INC COM 78667J108   20,698,870 1,005,776 SH   SOLE   1,005,776 0 0
SAREPTA THERAPEUTICS INC COM 803607100   11,398,317 94,030 SH   SOLE   94,030 0 0
STAAR SURGICAL CO COM 852312305   55,240,348 1,374,822 SH   SOLE   1,374,822 0 0
SYNDAX PHARMACEUTICALS INC COM 87164F105   6,862,152 472,600 SH   SOLE   472,600 0 0
TACTILE SYSTEMS TECHNOLOGY I COM 87357P100   380,755 27,100 SH   SOLE   27,100 0 0
TRAVERE THERAPEUTICS INC COM 89422G107   1,484,657 166,069 SH   SOLE   166,069 0 0
UNITED THERAPEUTICS CORP COM 91307C102   130,080,114 575,907 SH   SOLE   575,907 0 0
UROGEN PHARMA LTD COM M96088105   343,245 24,500 SH   SOLE   24,500 0 0
VANDA PHARMACEUTICALS INC COM 921659108   1,205,215 278,985 SH   SOLE   278,985 0 0