0001306923-18-000016.txt : 20180814 0001306923-18-000016.hdr.sgml : 20180814 20180814162839 ACCESSION NUMBER: 0001306923-18-000016 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20180630 FILED AS OF DATE: 20180814 DATE AS OF CHANGE: 20180814 EFFECTIVENESS DATE: 20180814 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Palo Alto Investors LP CENTRAL INDEX KEY: 0001306923 IRS NUMBER: 770558164 STATE OF INCORPORATION: CA FISCAL YEAR END: 1231 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-11013 FILM NUMBER: 181018025 BUSINESS ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 BUSINESS PHONE: 650-325-0772 MAIL ADDRESS: STREET 1: 470 UNIVERSITY AVE CITY: PALO ALTO STATE: CA ZIP: 94301 FORMER COMPANY: FORMER CONFORMED NAME: Palo Alto Investors, LLC DATE OF NAME CHANGE: 20041025 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001306923 XXXXXXXX 06-30-2018 06-30-2018 false Palo Alto Investors LP

470 University Ave Palo Alto CA 94301

13F HOLDINGS REPORT 028-11013 N Angela Nguyen-Dinh 650-325-0772 /s/ Angela Nguyen-Dinh Palo Alto CA 08-14-2018 0 36 2502471 INFORMATION TABLE 2 infotable.xml ABIOMED INC COM 003654100 364181 890309 SH SOLE 890309 0 0 ACADIA PHARMACEUTICALS INC COM 004225108 25207 1650780 SH SOLE 1650780 0 0 AIMMUNE THERAPEUTICS INC COM 00900T107 37155 1381759 SH SOLE 1381759 0 0 ALDER BIOPHARMACEUTICALS INC COM 014339105 29279 1853101 SH SOLE 1853101 0 0 ALEXION PHARMACEUTICALS INC COM 015351109 147295 1186427 SH SOLE 1186427 0 0 ALIGN TECHNOLOGY INC COM 016255101 63161 184607 SH SOLE 184607 0 0 ALIMERA SCIENCES INC COM 016259103 2948 3013793 SH SOLE 3013793 0 0 AMAG PHARMACEUTICALS INC COM 00163U106 65146 3340806 SH SOLE 3340806 0 0 AMICUS THERAPEUTICS INC COM 03152W109 96350 6168347 SH SOLE 6168347 0 0 BIOMARIN PHARMACEUTICAL INC COM 09061G101 240156 2549431 SH SOLE 2549431 0 0 CELGENE CORP COM 151020104 31358 394840 SH SOLE 394840 0 0 CLOVIS ONCOLOGY INC COM 189464100 226168 4974007 SH SOLE 4974007 0 0 CYTOKINETICS INC COM NEW 23282W605 1027 123686 SH SOLE 123686 0 0 DICERNA PHARMACEUTICALS INC COM 253031108 6136 500913 SH SOLE 500913 0 0 EPIZYME INC COM 29428V104 93578 6906158 SH SOLE 6906158 0 0 EXACT SCIENCES CORP COM 30063P105 18733 313320 SH SOLE 313320 0 0 GILEAD SCIENCES INC COM 375558103 12461 175900 SH SOLE 175900 0 0 HISTOGENICS CORP COM 43358V109 757 302922 SH SOLE 302922 0 0 IDERA PHARMACEUTICALS INC COM NEW 45168K306 814 616355 SH SOLE 616355 0 0 IMMUNOMEDICS INC COM 452907108 113696 4803364 SH SOLE 4803364 0 0 INSMED INC COM PAR $.01 457669307 171145 7236583 SH SOLE 7236583 0 0 KARYOPHARM THERAPEUTICS INC COM 48576U106 79230 4663324 SH SOLE 4663324 0 0 MELINTA THERAPEUTICS INC COM 58549G100 322 50689 SH SOLE 50689 0 0 MOMENTA PHARMACEUTICALS INC COM 60877T100 37496 1833532 SH SOLE 1833532 0 0 PROTHENA CORP PLC SHS G72800108 16086 1103325 SH SOLE 1103325 0 0 RIGEL PHARMACEUTICALS INC COM NEW 766559603 11224 3966087 SH SOLE 3966087 0 0 SAGE THERAPEUTICS INC COM 78667J108 130317 832536 SH SOLE 832536 0 0 SHIRE PLC SPONSORED ADR 82481R106 32275 191200 SH SOLE 191200 0 0 SOPHIRIS BIO INC COM NEW 83578Q209 694 247000 SH SOLE 247000 0 0 STAAR SURGICAL CO COM PAR $0.01 852312305 109169 3521565 SH SOLE 3521565 0 0 SUNESIS PHARMACEUTICALS INC COM PAR 867328700 2464 1162473 SH SOLE 1162473 0 0 TREVENA INC COM 89532E109 491 341300 SH SOLE 341300 0 0 UNITED THERAPEUTICS CORP DEL COM 91307C102 183895 1625234 SH SOLE 1625234 0 0 VANDA PHARMACEUTICALS INC COM 921659108 79166 4155670 SH SOLE 4155670 0 0 WRIGHT MED GROUP N V ORD SHS 0.03 PAR N96617118 71587 2757587 SH SOLE 2757587 0 0 ZOGENIX INC COM NEW 98978L204 1304 29500 SH SOLE 29500 0 0