The Securities and Exchange Commission has not necessarily reviewed the information in this filing and has not determined if it is accurate and complete.
The reader should not assume that the information is accurate and complete.

UNITED STATES SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM 13F

FORM 13F INFORMATION TABLE
OMB APPROVAL
OMB Number: 3235-0006
Estimated average burden
hours per response: 23.8
COLUMN 1 COLUMN 2 COLUMN 3 COLUMN 4 COLUMN 5 COLUMN 6 COLUMN 7 COLUMN 8
VALUE SHRS OR SH/ PUT/ INVESTMENT OTHER VOTING AUTHORITY
NAME OF ISSUER TITLE OF CLASS CUSIP (x$1000) PRN AMT PRN CALL DISCRETION MANAGER SOLE SHARED NONE
ABIOMED INC COM 003654100 57,348 2,202,289 SH   SOLE 2,202,289 0 0
ALIGN TECHNOLOGY INC COM 016255101 403 7,788 SH   SOLE 7,788 0 0
ALIMERA SCIENCES INC COM 016259103 28,680 3,634,984 SH   SOLE 3,634,984 0 0
AMAG PHARMACEUTICALS INC COM 00163U106 31,241 1,614,536 SH   SOLE 1,614,536 0 0
AMICUS THERAPEUTICS INC COM 03152W109 8,221 3,971,576 SH   SOLE 3,971,576 0 0
ANACOR PHARMACEUTICALS INC COM 032420101 31,457 1,572,078 SH   SOLE 1,572,078 0 0
ARIAD PHARMACEUTICALS INC COM 04033A100 27,877 3,458,624 SH   SOLE 3,458,624 0 0
AUXILIUM PHARMACEUTICALS INC COM 05334D107 131,606 4,842,031 SH   SOLE 4,842,031 0 0
AVEO PHARMACEUTICALS INC COM 053588109 2,137 1,429,174 SH   SOLE 1,429,174 0 0
BIOMARIN PHARMACEUTICAL INC COM 09061G101 50,863 745,687 SH   SOLE 745,687 0 0
CELGENE CORP COM 151020104 362 2,590 SH   SOLE 2,590 0 0
CELLADON CORP COM 15117E107 17,779 1,491,500 SH   SOLE 1,491,500 0 0
CLOVIS ONCOLOGY INC COM 189464100 12,947 186,900 SH   SOLE 186,900 0 0
CUBIST PHARMACEUTICALS INC COM 229678107 100,158 1,369,211 SH   SOLE 1,369,211 0 0
CYBERONICS INC COM 23251P102 111,701 1,711,730 SH   SOLE 1,711,730 0 0
CYTOKINETICS INC COM NEW 23282W605 2,348 247,186 SH   SOLE 247,186 0 0
EXACT SCIENCES CORP COM 30063P105 11,020 777,676 SH   SOLE 777,676 0 0
GERON CORP COM 374163103 1,060 507,300 SH   SOLE 507,300 0 0
GILEAD SCIENCES INC COM 375558103 255 3,600 SH   SOLE 3,600 0 0
HYPERION THERAPEUTICS INC COM 44915N101 1,618 62,700 SH   SOLE 62,700 0 0
INSMED INC COM PAR $.01 457669307 6,030 316,699 SH   SOLE 316,699 0 0
INTERMUNE INC COM 45884X103 147,893 4,418,662 SH   SOLE 4,418,662 0 0
KYTHERA BIOPHARMACEUTICALS I COM 501570105 35,993 905,259 SH   SOLE 905,259 0 0
MOMENTA PHARMACEUTICALS INC COM 60877T100 15,319 1,314,976 SH   SOLE 1,314,976 0 0
NPS PHARMACEUTICALS INC COM 62936P103 13,026 435,200 SH   SOLE 435,200 0 0
OREXIGEN THERAPEUTICS INC COM 686164104 10,849 1,669,024 SH   SOLE 1,669,024 0 0
PROTHENA CORP PLC SHS G72800108 20,416 532,918 SH   SOLE 532,918 0 0
QLT INC COM 746927102 11,348 2,041,043 SH   SOLE 2,041,043 0 0
QUESTCOR PHARMACEUTICALS INC COM 74835Y101 62,949 969,495 SH   SOLE 969,495 0 0
REVANCE THERAPEUTICS INC COM 761330109 2,888 91,669 SH   SOLE 91,669 0 0
RIGEL PHARMACEUTICALS INC COM NEW 766559603 20,057 5,169,301 SH   SOLE 5,169,301 0 0
SEQUENOM INC COM NEW 817337405 23,982 9,788,442 SH   SOLE 9,788,442 0 0
SHIRE PLC SPONSORED ADR 82481R106 267 1,800 SH   SOLE 1,800 0 0
SOPHIRIS BIO INC COM NEW 83578Q209 975 292,900 SH   SOLE 292,900 0 0
SPECTRUM PHARMACEUTICALS INC COM 84763A108 3,154 402,285 SH   SOLE 402,285 0 0
STAAR SURGICAL CO COM PAR $0.01 852312305 48,761 2,593,653 SH   SOLE 2,593,653 0 0
UNITED THERAPEUTICS CORP DEL COM 91307C102 103,530 1,101,028 SH   SOLE 1,101,028 0 0
VANDA PHARMACEUTICALS INC COM 921659108 52,251 3,215,424 SH   SOLE 3,215,424 0 0
XOMA CORP DEL COM 98419J107 1,334 256,100 SH   SOLE 256,100 0 0