Income Taxes (Tables)

12 Months Ended

Dec. 31, 2015

Schedule of income before income tax, domestic and foreign

For financial reporting purposes, income (loss) before income taxes for the years ended December 31, 2015, 2014 and 2013 include the following components (in thousands):



	Years ended December 31,
	2015			2014			2013
Income (loss) from continuing operations before income taxes:
U.S.	$	(50,155	)	$	(40,328	)	$	(44,104	)
Non‑U.S.	(7,050		)	(5,353		)	(3,756		)
	$	(57,205	)	$	(45,681	)	$	(47,860	)

Schedule of components of income tax expense (benefit)

Significant components of the provision for income taxes for the years ended December 31, 2015, 2014 and 2013 were as follows (in thousands):



	Years ended December 31,
	2015		2014		2013
Current:
Federal	$	—	$	—	$	—
State	—		—		—
Foreign	41		41		29
	41		41		29
Deferred:
Federal	—		—		—
State	—		—		—
Foreign	—		—		—

Total	$	41	$	41	$	29

Schedule of effective income tax rate reconciliation

A reconciliation of the income tax expense (benefit) at the statutory federal income tax rate as reflected in the financial statements was as follows:



	Years ended December 31,
	2015		2014		2013
Tax at U.S. statutory rate	(34.00	)%	(34.00	)%	(34.00	)%
State taxes, net of federal benefits	(2.27	)	(2.36	)	(2.32	)
Tax credit	(0.85	)	(8.59	)	(0.05	)
Change in valuation allowance	31.07		37.49		31.24
Rate change	0.01		(0.02	)	0.17
Other	6.11		7.58		5.03
	0.07	%	0.10	%	0.07	%

Schedule of deferred tax assets and liabilities

Significant components of the Company’s deferred tax assets (liabilities) consisted of the following (in thousands):



	Years ended December 31,
	2015			2014
Deferred tax assets:
Federal and state net operating loss carryforwards	$	99,823		$	83,339
Foreign net operating loss carryforwards	2,973			2,758
Accrued expenses	—			183
Credits	4,483			3,995
Other	4,138			3,272
Total deferred tax assets	111,417			93,547
Valuation allowance	(110,518		)	(92,789		)
Net deferred tax assets	899			758
Deferred tax liabilities:
Fixed assets	(612		)	(350		)
Intangibles	(287		)	(359		)
Other	—			(49		)
Net deferred tax liabilities	(899		)	(758		)
Net deferred tax assets	$	—		$	—
Current net deferred tax asset	15			13
Long‑term net deferred tax liability	(15		)	(13		)
Net deferred tax asset	$	—		$	—

Schedule of unrecognized tax benefits

Unrecognized tax benefits during the three years ended December 31, 2015, 2014 and 2013 consisted of the following:



	Years ended December 31,
	2015		2014		2013
Unrecognized tax benefits beginning of year	$	2,466	$	1,109	$	—
Gross change for current year positions	1,264		1,357		1,109
Decrease for prior period positions	—		—		—
Decrease due to settlements and payments	—		—		—
Decrease due to statute limitations	—		—		—
Unrecognized tax benefits end of the year	$	3,730	$	2,466	$	1,109