Commitments and Contingencies (Tables)

12 Months Ended

Dec. 31, 2015

Commitments and Contingencies Disclosure [Abstract]

Schedule of future minimum rental payments under the entity's non-cancellable operating leases

The future minimum rental payments under the Company’s non-cancellable operating leases for real estate as of December 31, 2015 were as follows (in thousands):

Year	Minimum lease Payments
2016	$	1,615
2017	789
2018	364
2019-2022	1,253
	$	4,021

Contractual obligation, fiscal year maturity schedule

The following table summarizes the Company's contractual obligations as of the year ended December 31, 2015 (in thousands):

	Payment Due by Period
Contractual Obligations	Total		Less than 1 year		Years 2 to 3		Years 4 to 5		After 5 years
Senior secured debt (1)	$	481	$	299	$	182	$	—	$	—
Operating lease obligations - real estate (2)	4,021		1,615		1,153		1,253		—
Other (3)	3,077		609		1,043		750		675
Total (4)	$	7,579	$	2,523	$	2,378	$	2,003	$	675

_{(1) Represents amounts payable under the MDFA facility.}

_{(2) Represents operating lease commitments for office and manufacturing space in Bedford and Wilmington, Massachusetts.}

_{(3) Represents amounts payable under our product royalty agreements, operating leases for office equipment and contracts for marketing exhibit services and a software development collaboration project}

_{(4) This table does not include: (a) revenue share obligations to past and present members of our scientific advisory board and our Chief Executive Officer, as the amounts of such payments are not known with certainty; and (b) contracts that are entered into in the ordinary course of business that are not material in the aggregate in any period presented above. See "—Revenue share agreements" and "Certain Relationships and Related-Persons Transactions—Revenue share agreement with Dr. Lang" for a description of our revenue share arrangements.}