<?xml version="1.0" encoding="UTF-8"?>

<!--XBRL Document Created with Wdesk from Workiva-->
<!--Copyright 2023 Workiva-->
<!--r:14a6f95b-ae5e-40bf-b3ba-5dbd2f40db5a,g:71b8c4aa-4329-4a14-8bfc-c04ca8bcb3cb-->
<link:linkbase xmlns:link="http://www.xbrl.org/2003/linkbase" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.xbrl.org/2003/linkbase http://www.xbrl.org/2003/xbrl-linkbase-2003-12-31.xsd">
  <link:roleRef roleURI="http://www.conformis.com/role/Cover" xlink:type="simple" xlink:href="cfms-20230331.xsd#Cover"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/Cover" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CoverAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentType_1ca35e9c-b431-4e99-b453-11c0a4294fdc" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentType"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentType_1ca35e9c-b431-4e99-b453-11c0a4294fdc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentQuarterlyReport_a57d032d-1d43-471e-a84e-89365718b142" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentQuarterlyReport"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentQuarterlyReport_a57d032d-1d43-471e-a84e-89365718b142" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentPeriodEndDate_107ab128-1282-4b69-961d-55934f89167c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentPeriodEndDate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentPeriodEndDate_107ab128-1282-4b69-961d-55934f89167c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentTransitionReport_e82e413e-30d7-4053-ba4a-2f715979cee0" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentTransitionReport"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentTransitionReport_e82e413e-30d7-4053-ba4a-2f715979cee0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFileNumber_52cb1f6a-e3cf-45d0-b943-8351dd94b1b3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFileNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityFileNumber_52cb1f6a-e3cf-45d0-b943-8351dd94b1b3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityRegistrantName_9907940f-643e-45c2-9aa4-fc2c28a559cf" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityRegistrantName"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityRegistrantName_9907940f-643e-45c2-9aa4-fc2c28a559cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityIncorporationStateCountryCode_71a90029-ffaa-4d82-b577-44d72ac06242" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityIncorporationStateCountryCode"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityIncorporationStateCountryCode_71a90029-ffaa-4d82-b577-44d72ac06242" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityTaxIdentificationNumber_f4c68f72-7f5e-40b8-ac3f-2576c4b878d3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityTaxIdentificationNumber"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityTaxIdentificationNumber_f4c68f72-7f5e-40b8-ac3f-2576c4b878d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressAddressLine1_a61b266b-0048-4176-8b15-6a4444874a5d" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressAddressLine1"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityAddressAddressLine1_a61b266b-0048-4176-8b15-6a4444874a5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressCityOrTown_31b392ae-36e5-4b49-a44a-243b8236c952" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressCityOrTown"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityAddressCityOrTown_31b392ae-36e5-4b49-a44a-243b8236c952" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressStateOrProvince_21adebae-cb99-43c9-98a7-23ef6fde4dd3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressStateOrProvince"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityAddressStateOrProvince_21adebae-cb99-43c9-98a7-23ef6fde4dd3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityAddressPostalZipCode_1dd7119b-7feb-4919-89ab-2f5c4a9cf8f4" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityAddressPostalZipCode"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityAddressPostalZipCode_1dd7119b-7feb-4919-89ab-2f5c4a9cf8f4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CityAreaCode_9b2518a1-3d46-4316-8bcd-e2bdaeae124c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CityAreaCode"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_CityAreaCode_9b2518a1-3d46-4316-8bcd-e2bdaeae124c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_LocalPhoneNumber_372cb854-a173-4014-af3e-f867d270d4f8" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_LocalPhoneNumber"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_LocalPhoneNumber_372cb854-a173-4014-af3e-f867d270d4f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCurrentReportingStatus_6e711c87-875d-4743-b016-fcad7bd17ef3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCurrentReportingStatus"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityCurrentReportingStatus_6e711c87-875d-4743-b016-fcad7bd17ef3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityInteractiveDataCurrent_d2cb1136-e450-4859-b941-c944745744d3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityInteractiveDataCurrent"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityInteractiveDataCurrent_d2cb1136-e450-4859-b941-c944745744d3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityFilerCategory_bf688292-5ea1-4604-b455-f447e966c014" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityFilerCategory"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityFilerCategory_bf688292-5ea1-4604-b455-f447e966c014" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntitySmallBusiness_6fdf32fe-1251-42a6-9f91-8a3a4bb287e3" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntitySmallBusiness"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntitySmallBusiness_6fdf32fe-1251-42a6-9f91-8a3a4bb287e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityEmergingGrowthCompany_13f98a61-c5e0-4d09-bbe8-c2257f2023b6" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityEmergingGrowthCompany"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityEmergingGrowthCompany_13f98a61-c5e0-4d09-bbe8-c2257f2023b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityShellCompany_94ad0446-872c-42b8-af14-107c74e7a7be" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityShellCompany"/>
    <link:presentationArc order="20" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityShellCompany_94ad0446-872c-42b8-af14-107c74e7a7be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_Security12bTitle_ef0104a2-49bc-48b0-983a-81578e24919f" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_Security12bTitle"/>
    <link:presentationArc order="21" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_Security12bTitle_ef0104a2-49bc-48b0-983a-81578e24919f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_TradingSymbol_74da0cd9-f90c-4c88-87af-c5582094e01c" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_TradingSymbol"/>
    <link:presentationArc order="22" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_TradingSymbol_74da0cd9-f90c-4c88-87af-c5582094e01c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCommonStockSharesOutstanding_f1489610-9147-4735-be06-ad1aac52fb6a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCommonStockSharesOutstanding"/>
    <link:presentationArc order="23" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityCommonStockSharesOutstanding_f1489610-9147-4735-be06-ad1aac52fb6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_EntityCentralIndexKey_9ff2e5ee-6634-476c-ae0d-091efee29322" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_EntityCentralIndexKey"/>
    <link:presentationArc order="24" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_EntityCentralIndexKey_9ff2e5ee-6634-476c-ae0d-091efee29322" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_CurrentFiscalYearEndDate_75ce7f63-a0e6-4423-969c-6565a2e39adf" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_CurrentFiscalYearEndDate"/>
    <link:presentationArc order="25" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_CurrentFiscalYearEndDate_75ce7f63-a0e6-4423-969c-6565a2e39adf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalYearFocus_3523e600-10d1-40a5-a3cf-f8a8ea4d0841" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalYearFocus"/>
    <link:presentationArc order="26" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentFiscalYearFocus_3523e600-10d1-40a5-a3cf-f8a8ea4d0841" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_DocumentFiscalPeriodFocus_9a96fa52-4860-4ad9-be69-8d01f57cbf3a" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_DocumentFiscalPeriodFocus"/>
    <link:presentationArc order="27" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_DocumentFiscalPeriodFocus_9a96fa52-4860-4ad9-be69-8d01f57cbf3a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_dei_AmendmentFlag_4d50f0f8-873d-4c00-94ac-6f00004a8c80" xlink:href="https://xbrl.sec.gov/dei/2022/dei-2022.xsd#dei_AmendmentFlag"/>
    <link:presentationArc order="28" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_dei_CoverAbstract_f4313f90-d79a-4675-9f2f-cf8663ebca9e" xlink:to="loc_dei_AmendmentFlag_4d50f0f8-873d-4c00-94ac-6f00004a8c80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedBalanceSheets" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedBalanceSheets"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedBalanceSheets" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_8d48c331-9f60-43f6-8e24-63bb27c3e8c2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_8d48c331-9f60-43f6-8e24-63bb27c3e8c2" xlink:to="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:to="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_c5fcf1dc-7493-48bc-9e24-d613ec5ead18" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_c5fcf1dc-7493-48bc-9e24-d613ec5ead18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_55c7df03-db94-4720-a549-6eb7f28829f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_55c7df03-db94-4720-a549-6eb7f28829f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RoyaltyReceivable_1946ffab-34e6-4c7f-9fd0-9afd9e943c7f" xlink:href="cfms-20230331.xsd#cfms_RoyaltyReceivable"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_cfms_RoyaltyReceivable_1946ffab-34e6-4c7f-9fd0-9afd9e943c7f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_fb540dc4-7ab8-4644-b4fe-fe6c55a72adc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_us-gaap_InventoryNet_fb540dc4-7ab8-4644-b4fe-fe6c55a72adc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_6f883c9c-8f69-4c88-a1fc-79816229014f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PrepaidExpenseAndOtherAssetsCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_us-gaap_PrepaidExpenseAndOtherAssetsCurrent_6f883c9c-8f69-4c88-a1fc-79816229014f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AssetsCurrent_74e04534-0815-434f-a50f-557b00d36862" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AssetsCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsCurrentAbstract_64b62082-5d61-4b48-baef-7e468b799da4" xlink:to="loc_us-gaap_AssetsCurrent_74e04534-0815-434f-a50f-557b00d36862" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_14c53bd0-013a-4c62-a417-36ea1614d5bb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_14c53bd0-013a-4c62-a417-36ea1614d5bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAsset_41b369d0-c899-4240-909f-b0c79ba0a351" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAsset"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAsset_41b369d0-c899-4240-909f-b0c79ba0a351" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrentAbstract_0d3314d3-7fd5-467c-9305-35ac3de63c9d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsNoncurrentAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:to="loc_us-gaap_OtherAssetsNoncurrentAbstract_0d3314d3-7fd5-467c-9305-35ac3de63c9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_e1b5df96-68f7-48e4-86b7-e9f7842ef0b1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentAbstract_0d3314d3-7fd5-467c-9305-35ac3de63c9d" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_e1b5df96-68f7-48e4-86b7-e9f7842ef0b1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAssetsNoncurrent_0b493837-ac8e-425c-9bd6-5ddca2621165" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAssetsNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherAssetsNoncurrentAbstract_0d3314d3-7fd5-467c-9305-35ac3de63c9d" xlink:to="loc_us-gaap_OtherAssetsNoncurrent_0b493837-ac8e-425c-9bd6-5ddca2621165" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Assets_85d2d8a3-e80d-48e8-a30e-202caac19c32" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Assets"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AssetsAbstract_8c3eda2a-f511-4e4d-a700-7daf3e7d5699" xlink:to="loc_us-gaap_Assets_85d2d8a3-e80d-48e8-a30e-202caac19c32" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquityAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_8d48c331-9f60-43f6-8e24-63bb27c3e8c2" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrentAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableCurrent_fa3bb12c-87bb-4f19-8176-7689259d6296" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:to="loc_us-gaap_AccountsPayableCurrent_fa3bb12c-87bb-4f19-8176-7689259d6296" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_5400694f-4c8f-463a-bc2a-93d5ff9e5048" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_5400694f-4c8f-463a-bc2a-93d5ff9e5048" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityCurrent_72b79014-bf47-41d4-ad30-4b116f3cfbb3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:to="loc_us-gaap_OperatingLeaseLiabilityCurrent_72b79014-bf47-41d4-ad30-4b116f3cfbb3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesCurrent_5523b664-8118-48c7-98f3-6e814f7b736b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:to="loc_us-gaap_LiabilitiesCurrent_5523b664-8118-48c7-98f3-6e814f7b736b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherLiabilitiesNoncurrent_185b4b17-fbcc-460d-9b69-59353de50e5a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherLiabilitiesNoncurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesCurrentAbstract_9dbab2da-6b86-47ee-8164-95ef6ce2c41c" xlink:to="loc_us-gaap_OtherLiabilitiesNoncurrent_185b4b17-fbcc-460d-9b69-59353de50e5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtNoncurrent_4de93f08-070f-4605-8c88-7a6a481a214d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtNoncurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_LongTermDebtNoncurrent_4de93f08-070f-4605-8c88-7a6a481a214d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_f0687e3a-8ca4-44e6-bff3-878f47babdd8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiabilityNoncurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_OperatingLeaseLiabilityNoncurrent_f0687e3a-8ca4-44e6-bff3-878f47babdd8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Liabilities_61abaf71-e953-4f56-b2a8-ea6b445e0409" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Liabilities"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_Liabilities_61abaf71-e953-4f56-b2a8-ea6b445e0409" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingencies_549c923e-c22b-4927-9151-c1da42ace077" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingencies"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_CommitmentsAndContingencies_549c923e-c22b-4927-9151-c1da42ace077" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityAbstract"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockValue_d401e685-037b-44c5-a564-a89b0061163e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_PreferredStockValue_d401e685-037b-44c5-a564-a89b0061163e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockValue_94201955-1189-4686-8f96-780f26991abb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_CommonStockValue_94201955-1189-4686-8f96-780f26991abb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapital_8467d311-d394-4008-8266-68adb7b3e8fe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapital"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_AdditionalPaidInCapital_8467d311-d394-4008-8266-68adb7b3e8fe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_46b52ffe-b46d-4e6f-8c15-cb06c1d114c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_46b52ffe-b46d-4e6f-8c15-cb06c1d114c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_4c990d4c-b79d-4b13-a7c4-a3faa915db60" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeLossNetOfTax_4c990d4c-b79d-4b13-a7c4-a3faa915db60" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_41599848-bb6d-41a9-9b68-b8a89c0efa0e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StockholdersEquityAbstract_82137db0-b8d2-4b13-9bb4-7f084af5065f" xlink:to="loc_us-gaap_StockholdersEquity_41599848-bb6d-41a9-9b68-b8a89c0efa0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LiabilitiesAndStockholdersEquity_74a52181-4035-4a19-acae-34a61da8d67d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LiabilitiesAndStockholdersEquity"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LiabilitiesAndStockholdersEquityAbstract_e5b4ce96-4ab4-4ab1-8c71-82ac6d0813c8" xlink:to="loc_us-gaap_LiabilitiesAndStockholdersEquity_74a52181-4035-4a19-acae-34a61da8d67d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedBalanceSheetsParenthetical"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedBalanceSheetsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfFinancialPositionAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_febfa357-25be-4472-acfa-ee9b48f75408" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_febfa357-25be-4472-acfa-ee9b48f75408" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_c425ceeb-a8dd-4f40-a3fe-8e249ef293bd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_c425ceeb-a8dd-4f40-a3fe-8e249ef293bd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_86f6d5b4-0f5c-475c-aaf8-c858decf991b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_PreferredStockSharesIssued_86f6d5b4-0f5c-475c-aaf8-c858decf991b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_fffddcc8-4f76-4ff1-9724-4292f23c17f6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_fffddcc8-4f76-4ff1-9724-4292f23c17f6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_a795ab09-5a15-49a6-a329-9d8d23182afa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_a795ab09-5a15-49a6-a329-9d8d23182afa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_22fe8e05-b4d8-41b8-94fa-e58d477b0842" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_22fe8e05-b4d8-41b8-94fa-e58d477b0842" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesIssued_f9992e4f-9616-4b54-b809-7d65d14f7e2e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesIssued"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_CommonStockSharesIssued_f9992e4f-9616-4b54-b809-7d65d14f7e2e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_41bc16e4-937a-433d-aaa1-0b350dca462b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfFinancialPositionAbstract_9bd310e4-4267-4e75-9032-8755d9a8d7e5" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_41bc16e4-937a-433d-aaa1-0b350dca462b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofOperations" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofOperations"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofOperations" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_fc0e4bae-832e-41ec-bf54-561950e6263f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_37feac1f-5ac7-48b7-9a60-2496cddb685c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_fc0e4bae-832e-41ec-bf54-561950e6263f" xlink:to="loc_us-gaap_StatementTable_37feac1f-5ac7-48b7-9a60-2496cddb685c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_c5a5f774-4f93-4403-b591-966914800262" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_37feac1f-5ac7-48b7-9a60-2496cddb685c" xlink:to="loc_srt_ProductOrServiceAxis_c5a5f774-4f93-4403-b591-966914800262" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_b519f1c4-b13a-4b67-9160-05fe70faa8e9" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_c5a5f774-4f93-4403-b591-966914800262" xlink:to="loc_srt_ProductsAndServicesDomain_b519f1c4-b13a-4b67-9160-05fe70faa8e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_1d11740e-1df9-429b-aa29-deca49fec8e2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_b519f1c4-b13a-4b67-9160-05fe70faa8e9" xlink:to="loc_us-gaap_ProductMember_1d11740e-1df9-429b-aa29-deca49fec8e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RoyaltyMember_ed2ecd35-8a4b-4ee0-88f3-1bc611381e6b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RoyaltyMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_b519f1c4-b13a-4b67-9160-05fe70faa8e9" xlink:to="loc_us-gaap_RoyaltyMember_ed2ecd35-8a4b-4ee0-88f3-1bc611381e6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_37feac1f-5ac7-48b7-9a60-2496cddb685c" xlink:to="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesAbstract_1eeb3660-155d-40ab-a957-7889d94f4a79" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenuesAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_RevenuesAbstract_1eeb3660-155d-40ab-a957-7889d94f4a79" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_cda8ce63-c491-4d75-87fd-f17f690d6bf7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesAbstract_1eeb3660-155d-40ab-a957-7889d94f4a79" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_cda8ce63-c491-4d75-87fd-f17f690d6bf7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfRevenue_36ef81f0-5339-4a8f-8d9f-d479365fd053" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfRevenue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_CostOfRevenue_36ef81f0-5339-4a8f-8d9f-d479365fd053" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GrossProfit_c269d146-934b-4d57-b3ff-569e63e16f6c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GrossProfit"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_GrossProfit_c269d146-934b-4d57-b3ff-569e63e16f6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpensesAbstract"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpense_a165287a-b409-417b-bb75-f7ce239beef6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingAndMarketingExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:to="loc_us-gaap_SellingAndMarketingExpense_a165287a-b409-417b-bb75-f7ce239beef6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpense_c5f0e40d-2f9c-4db7-bb49-e01a733d864f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpense_c5f0e40d-2f9c-4db7-bb49-e01a733d864f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpense_4599b106-b45a-4d9e-acaf-9f4c16271134" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GeneralAndAdministrativeExpense"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpense_4599b106-b45a-4d9e-acaf-9f4c16271134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingExpenses_d91636fc-3a87-460b-a95a-32a62102db3b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingExpenses"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:to="loc_us-gaap_OperatingExpenses_d91636fc-3a87-460b-a95a-32a62102db3b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingIncomeLoss_b704b9ee-fe57-4805-9c98-98e138aed2de" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OperatingExpensesAbstract_8e7b91f9-911a-4989-819d-5a4f96f6b055" xlink:to="loc_us-gaap_OperatingIncomeLoss_b704b9ee-fe57-4805-9c98-98e138aed2de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherIncomeAndExpensesAbstract"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InvestmentIncomeInterest_5d705ead-c9f5-4cf5-8cbe-40b8dfe97e4c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InvestmentIncomeInterest"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:to="loc_us-gaap_InvestmentIncomeInterest_5d705ead-c9f5-4cf5-8cbe-40b8dfe97e4c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestExpense_cc2510a0-1738-4b73-9c27-365effebb0e3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestExpense"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:to="loc_us-gaap_InterestExpense_cc2510a0-1738-4b73-9c27-365effebb0e3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_6a124857-cff4-4d95-b4f3-53f835ede3aa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ForeignCurrencyTransactionGainLossBeforeTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossBeforeTax_6a124857-cff4-4d95-b4f3-53f835ede3aa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_NonoperatingIncomeExpenseNetOfInterestExpense_b265f670-ab43-4207-b214-81ed72de94bb" xlink:href="cfms-20230331.xsd#cfms_NonoperatingIncomeExpenseNetOfInterestExpense"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherIncomeAndExpensesAbstract_804475c9-12aa-4832-9cb8-2dcd91ec1d3e" xlink:to="loc_cfms_NonoperatingIncomeExpenseNetOfInterestExpense_b265f670-ab43-4207-b214-81ed72de94bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_30208b15-5593-4f56-9076-7ff1c633c095" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_IncomeLossFromContinuingOperationsBeforeIncomeTaxesExtraordinaryItemsNoncontrollingInterest_30208b15-5593-4f56-9076-7ff1c633c095" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExpenseBenefit_611b2b75-b70d-4978-bd0f-d60516e6edad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExpenseBenefit"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_IncomeTaxExpenseBenefit_611b2b75-b70d-4978-bd0f-d60516e6edad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_2ca7223f-5c15-4675-a5e8-eb9d3b47f10c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_NetIncomeLoss_2ca7223f-5c15-4675-a5e8-eb9d3b47f10c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_58b38e2c-8161-46b3-bfba-ccd8ad689fc7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_EarningsPerShareBasic_58b38e2c-8161-46b3-bfba-ccd8ad689fc7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_ae936cba-8ba7-4eb0-b268-b65b4e902a92" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_EarningsPerShareDiluted_ae936cba-8ba7-4eb0-b268-b65b4e902a92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_d86cac1a-9ab1-4dee-b43e-6b3bb81e6b1a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_d86cac1a-9ab1-4dee-b43e-6b3bb81e6b1a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_20b5861c-ba30-4027-a661-55d41d854156" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_baf84867-a21f-4fae-ab62-2762f6cab714" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_20b5861c-ba30-4027-a661-55d41d854156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofComprehensiveLossIncome" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofComprehensiveLossIncome"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofComprehensiveLossIncome" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_e52311c1-8931-45f9-9b7c-f78fdc754bdc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_10445252-2665-443d-afd9-788045bfa3e1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_e52311c1-8931-45f9-9b7c-f78fdc754bdc" xlink:to="loc_us-gaap_NetIncomeLoss_10445252-2665-443d-afd9-788045bfa3e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_591960b4-6172-4ac4-b8b4-fecd4022907d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_e52311c1-8931-45f9-9b7c-f78fdc754bdc" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_591960b4-6172-4ac4-b8b4-fecd4022907d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_ec38acf4-e22c-4d96-9ceb-33dc6339f852" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPeriodIncreaseDecreaseAbstract_591960b4-6172-4ac4-b8b4-fecd4022907d" xlink:to="loc_us-gaap_OtherComprehensiveIncomeForeignCurrencyTransactionAndTranslationAdjustmentNetOfTaxPortionAttributableToParent_ec38acf4-e22c-4d96-9ceb-33dc6339f852" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ComprehensiveIncomeNetOfTax_eb638f14-194d-46f8-9bea-2e97b517981c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ComprehensiveIncomeNetOfTax"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfIncomeAndComprehensiveIncomeAbstract_e52311c1-8931-45f9-9b7c-f78fdc754bdc" xlink:to="loc_us-gaap_ComprehensiveIncomeNetOfTax_eb638f14-194d-46f8-9bea-2e97b517981c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofChangesinStockholdersEquity" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofChangesinStockholdersEquity"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofChangesinStockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_1c429594-24e4-40a3-887f-5785300733f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementTable_47150d3a-268b-4505-84c7-f0e832920875" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_1c429594-24e4-40a3-887f-5785300733f5" xlink:to="loc_us-gaap_StatementTable_47150d3a-268b-4505-84c7-f0e832920875" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_f9fe3199-9d43-4be4-90f8-b7432a35e251" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_47150d3a-268b-4505-84c7-f0e832920875" xlink:to="loc_us-gaap_AwardTypeAxis_f9fe3199-9d43-4be4-90f8-b7432a35e251" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_a829e4d9-56c8-4fec-9881-b09a4c5b4cea" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_f9fe3199-9d43-4be4-90f8-b7432a35e251" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_a829e4d9-56c8-4fec-9881-b09a4c5b4cea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_194124b7-8099-44e1-b31f-c9f9f067496a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_a829e4d9-56c8-4fec-9881-b09a4c5b4cea" xlink:to="loc_us-gaap_RestrictedStockMember_194124b7-8099-44e1-b31f-c9f9f067496a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementEquityComponentsAxis_de727224-8759-4f4e-82a5-0f417d90805d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementEquityComponentsAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_47150d3a-268b-4505-84c7-f0e832920875" xlink:to="loc_us-gaap_StatementEquityComponentsAxis_de727224-8759-4f4e-82a5-0f417d90805d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityComponentDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementEquityComponentsAxis_de727224-8759-4f4e-82a5-0f417d90805d" xlink:to="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_6648e43c-9491-4df8-ad59-5c98f5b6b1c9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:to="loc_us-gaap_CommonStockMember_6648e43c-9491-4df8-ad59-5c98f5b6b1c9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdditionalPaidInCapitalMember_e167028b-ab6e-425b-afdd-0c3bb1bc2708" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdditionalPaidInCapitalMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:to="loc_us-gaap_AdditionalPaidInCapitalMember_e167028b-ab6e-425b-afdd-0c3bb1bc2708" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsMember_8fead014-351f-451e-ba22-dc3b13d4c628" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:to="loc_us-gaap_RetainedEarningsMember_8fead014-351f-451e-ba22-dc3b13d4c628" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_0ecb1e70-907e-4701-92b2-5a34d37667d9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedOtherComprehensiveIncomeMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityComponentDomain_b40a1635-0ba6-4365-a940-37d2c8f7fbb8" xlink:to="loc_us-gaap_AccumulatedOtherComprehensiveIncomeMember_0ecb1e70-907e-4701-92b2-5a34d37667d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementLineItems_2c4511d4-8ed7-4f2e-8e48-8da49fbd2a74" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementTable_47150d3a-268b-4505-84c7-f0e832920875" xlink:to="loc_us-gaap_StatementLineItems_2c4511d4-8ed7-4f2e-8e48-8da49fbd2a74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInStockholdersEquityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementLineItems_2c4511d4-8ed7-4f2e-8e48-8da49fbd2a74" xlink:to="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_a87e497d-1093-47b0-9664-d95dfe8bf742" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_a87e497d-1093-47b0-9664-d95dfe8bf742" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_1013f716-26d3-4f8d-b5a9-e1550426c485" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_StockholdersEquity_1013f716-26d3-4f8d-b5a9-e1550426c485" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_d29f595b-f2b7-4ba1-8478-a3eb5f0573bc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockIssuedDuringPeriodSharesNewIssues"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_StockIssuedDuringPeriodSharesNewIssues_d29f595b-f2b7-4ba1-8478-a3eb5f0573bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_e05580ac-a0bb-4b9d-ac96-cba84ad6f954" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_AdjustmentsToAdditionalPaidInCapitalSharebasedCompensationRequisiteServicePeriodRecognitionValue_e05580ac-a0bb-4b9d-ac96-cba84ad6f954" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_766fe144-a2e0-4495-b08b-12377a29196a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_NetIncomeLoss_766fe144-a2e0-4495-b08b-12377a29196a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_40aa752d-9440-494d-9c87-dfa7963c9fe5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_OtherComprehensiveIncomeLossNetOfTaxPortionAttributableToParent_40aa752d-9440-494d-9c87-dfa7963c9fe5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesOutstanding_dfb33881-fbc6-44ab-9647-aef298856809" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesOutstanding"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_CommonStockSharesOutstanding_dfb33881-fbc6-44ab-9647-aef298856809" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquity_7de1315d-da52-474a-adcf-f5f339be4483" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquity"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInStockholdersEquityRollForward_30ce3409-e1e7-4d1b-a77f-e88f799dad25" xlink:to="loc_us-gaap_StockholdersEquity_7de1315d-da52-474a-adcf-f5f339be4483" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofChangesinStockholdersEquityParenthetical" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofChangesinStockholdersEquityParenthetical"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofChangesinStockholdersEquityParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfStockholdersEquityAbstract_3d86de30-d6c8-4fa2-8e86-a1a978e54c8b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfStockholdersEquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_e4adbbda-a247-436e-9b08-ec13e13935c1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfStockholdersEquityAbstract_3d86de30-d6c8-4fa2-8e86-a1a978e54c8b" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_e4adbbda-a247-436e-9b08-ec13e13935c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofCashFlows" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofCashFlows"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofCashFlows" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StatementOfCashFlowsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_c1ee2b81-6738-4423-aa11-526483246a62" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_c1ee2b81-6738-4423-aa11-526483246a62" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLoss_4e26e7e3-e134-4141-bb56-05a89839991a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLoss"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_c1ee2b81-6738-4423-aa11-526483246a62" xlink:to="loc_us-gaap_NetIncomeLoss_4e26e7e3-e134-4141-bb56-05a89839991a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_c1ee2b81-6738-4423-aa11-526483246a62" xlink:to="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DepreciationDepletionAndAmortization_6294986b-c905-435c-a7ba-5968ee88e8b2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DepreciationDepletionAndAmortization"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_DepreciationDepletionAndAmortization_6294986b-c905-435c-a7ba-5968ee88e8b2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensation_7e2f3ad2-1c86-473c-b8eb-109949daa005" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensation"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_ShareBasedCompensation_7e2f3ad2-1c86-473c-b8eb-109949daa005" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_064ce015-97fc-420d-b142-cc28e46cf336" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ForeignCurrencyTransactionGainLossUnrealized"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_ForeignCurrencyTransactionGainLossUnrealized_064ce015-97fc-420d-b142-cc28e46cf336" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_2e7e4fcf-c449-4bae-8c09-2a71a1cf7b65" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_OperatingLeaseRightOfUseAssetAmortizationExpense_2e7e4fcf-c449-4bae-8c09-2a71a1cf7b65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProvisionForDoubtfulAccounts_652fc54e-3a0d-49af-88bd-8b551bf3fd20" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProvisionForDoubtfulAccounts"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_ProvisionForDoubtfulAccounts_652fc54e-3a0d-49af-88bd-8b551bf3fd20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_ed9a3ccf-d0b9-4a8f-8afa-b5736b0ff0f0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_ed9a3ccf-d0b9-4a8f-8afa-b5736b0ff0f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaidInKindInterest_9c9a013d-e5a8-4886-a021-b9e031626a34" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaidInKindInterest"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_PaidInKindInterest_9c9a013d-e5a8-4886-a021-b9e031626a34" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInOperatingCapitalAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AdjustmentsToReconcileNetIncomeLossToCashProvidedByUsedInOperatingActivitiesAbstract_7551c7e2-0e44-496a-97ac-04cde11df0f2" xlink:to="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_27e05f34-dc5f-4ac3-986a-954c5a6b72a6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsReceivable_27e05f34-dc5f-4ac3-986a-954c5a6b72a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_IncreaseDecreaseInRoyaltyReceivable_4396c5f9-adf3-4d59-b797-a0e948893e36" xlink:href="cfms-20230331.xsd#cfms_IncreaseDecreaseInRoyaltyReceivable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:to="loc_cfms_IncreaseDecreaseInRoyaltyReceivable_4396c5f9-adf3-4d59-b797-a0e948893e36" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInInventories_aff2a6f8-d173-45b6-aa7b-e4887e56b314" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInInventories"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:to="loc_us-gaap_IncreaseDecreaseInInventories_aff2a6f8-d173-45b6-aa7b-e4887e56b314" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_0b2c80ca-2a77-4874-9e65-0f9e10187180" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:to="loc_us-gaap_IncreaseDecreaseInPrepaidDeferredExpenseAndOtherAssets_0b2c80ca-2a77-4874-9e65-0f9e10187180" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_f908bddf-3e95-4cb3-a48f-1a9bbb582f68" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncreaseDecreaseInOperatingCapitalAbstract_b18c4305-e9a0-4ef0-a381-ec2448da236f" xlink:to="loc_us-gaap_IncreaseDecreaseInAccountsPayableAndAccruedLiabilities_f908bddf-3e95-4cb3-a48f-1a9bbb582f68" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a80e00f7-6312-42b6-accc-b1845eaf5b47" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInOperatingActivities"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInOperatingActivitiesContinuingOperationsAbstract_c1ee2b81-6738-4423-aa11-526483246a62" xlink:to="loc_us-gaap_NetCashProvidedByUsedInOperatingActivities_a80e00f7-6312-42b6-accc-b1845eaf5b47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_56d6c493-c12b-41a2-bfba-6e41e6308b2d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_56d6c493-c12b-41a2-bfba-6e41e6308b2d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_19a5c6b6-830a-4404-9425-84297e9df0e2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PaymentsToAcquirePropertyPlantAndEquipment"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_56d6c493-c12b-41a2-bfba-6e41e6308b2d" xlink:to="loc_us-gaap_PaymentsToAcquirePropertyPlantAndEquipment_19a5c6b6-830a-4404-9425-84297e9df0e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_bfc10cce-5820-4633-8f52-70c678fdb1de" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInInvestingActivities"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInInvestingActivitiesContinuingOperationsAbstract_56d6c493-c12b-41a2-bfba-6e41e6308b2d" xlink:to="loc_us-gaap_NetCashProvidedByUsedInInvestingActivities_bfc10cce-5820-4633-8f52-70c678fdb1de" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_9e7c5bcd-b8e0-4fc0-850d-b6e6bc3bc9f0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_9e7c5bcd-b8e0-4fc0-850d-b6e6bc3bc9f0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_37b15795-7e2e-41d8-a77f-63977d8d642e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetCashProvidedByUsedInFinancingActivities"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetCashProvidedByUsedInFinancingActivitiesContinuingOperationsAbstract_9e7c5bcd-b8e0-4fc0-850d-b6e6bc3bc9f0" xlink:to="loc_us-gaap_NetCashProvidedByUsedInFinancingActivities_37b15795-7e2e-41d8-a77f-63977d8d642e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_43c989b0-ef7c-49a2-9eaa-89c4b787ecba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_EffectOfExchangeRateOnCashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_43c989b0-ef7c-49a2-9eaa-89c4b787ecba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_d37dae0f-921a-45a7-8fa1-a01d78678d9b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalentsPeriodIncreaseDecreaseIncludingExchangeRateEffect_d37dae0f-921a-45a7-8fa1-a01d78678d9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4e95892e-9e0d-44db-909d-01bc7a2bc939" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_4e95892e-9e0d-44db-909d-01bc7a2bc939" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_969c5fe7-1845-4690-b986-04b05beffd3c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_969c5fe7-1845-4690-b986-04b05beffd3c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SupplementalCashFlowElementsAbstract_705f808d-4fdd-45d7-93dc-85029e78d70a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SupplementalCashFlowElementsAbstract"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_SupplementalCashFlowElementsAbstract_705f808d-4fdd-45d7-93dc-85029e78d70a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InterestPaidNet_69aabe49-99b0-4754-9c8f-2de128890fa3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InterestPaidNet"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SupplementalCashFlowElementsAbstract_705f808d-4fdd-45d7-93dc-85029e78d70a" xlink:to="loc_us-gaap_InterestPaidNet_69aabe49-99b0-4754-9c8f-2de128890fa3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_ae905c0c-8aa7-477d-bb8c-4ba752919f7c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_StatementOfCashFlowsAbstract_85bbcf54-5e0c-4c4f-9d4f-7429331418f4" xlink:to="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_ae905c0c-8aa7-477d-bb8c-4ba752919f7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_8ab4ff7f-1325-43cf-b796-19bac7284089" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CashFlowNoncashInvestingAndFinancingActivitiesDisclosureAbstract_ae905c0c-8aa7-477d-bb8c-4ba752919f7c" xlink:to="loc_us-gaap_RightOfUseAssetObtainedInExchangeForOperatingLeaseLiability_8ab4ff7f-1325-43cf-b796-19bac7284089" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/ConsolidatedStatementsofOperationsParenthetical" xlink:type="simple" xlink:href="cfms-20230331.xsd#ConsolidatedStatementsofOperationsParenthetical"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/ConsolidatedStatementsofOperationsParenthetical" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementAbstract_36cf1682-bde9-4712-8f65-79ad7c677d6d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_646a25dc-6460-44e9-a810-418cb7fca457" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementAbstract_36cf1682-bde9-4712-8f65-79ad7c677d6d" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_646a25dc-6460-44e9-a810-418cb7fca457" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/OrganizationandBasisofPresentation" xlink:type="simple" xlink:href="cfms-20230331.xsd#OrganizationandBasisofPresentation"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/OrganizationandBasisofPresentation" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_566274f4-a35c-4d1a-889d-dfc30f767411" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_74e344b1-0933-48f9-a060-276f29f1a2b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_566274f4-a35c-4d1a-889d-dfc30f767411" xlink:to="loc_us-gaap_BusinessDescriptionAndBasisOfPresentationTextBlock_74e344b1-0933-48f9-a060-276f29f1a2b6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPolicies" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPolicies"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_e1604629-be1b-415a-b86c-4013e69e3c10" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SignificantAccountingPoliciesTextBlock_c3909e18-b204-43be-bf62-cfccb148b039" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SignificantAccountingPoliciesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_e1604629-be1b-415a-b86c-4013e69e3c10" xlink:to="loc_us-gaap_SignificantAccountingPoliciesTextBlock_c3909e18-b204-43be-bf62-cfccb148b039" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccountsReceivable" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccountsReceivable"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccountsReceivable" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrentAbstract_966f0077-ae00-405c-99a7-89f29f34da60" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock_bdefb74b-3606-4dcf-8701-24d6699f0c98" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_966f0077-ae00-405c-99a7-89f29f34da60" xlink:to="loc_us-gaap_LoansNotesTradeAndOtherReceivablesDisclosureTextBlock_bdefb74b-3606-4dcf-8701-24d6699f0c98" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/Inventories" xlink:type="simple" xlink:href="cfms-20230331.xsd#Inventories"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/Inventories" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_87c63a5c-da27-4bc0-ab99-4ec57d3bc8b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureTextBlock_c15ebc74-70f5-4218-8e20-c8cfce166b9a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_87c63a5c-da27-4bc0-ab99-4ec57d3bc8b7" xlink:to="loc_us-gaap_InventoryDisclosureTextBlock_c15ebc74-70f5-4218-8e20-c8cfce166b9a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/PropertyandEquipment" xlink:type="simple" xlink:href="cfms-20230331.xsd#PropertyandEquipment"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/PropertyandEquipment" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_8eb32fa2-4cc1-45be-9838-614adf1aa82e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_020a754a-43b8-4ba1-b755-a748b0c00099" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_8eb32fa2-4cc1-45be-9838-614adf1aa82e" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentDisclosureTextBlock_020a754a-43b8-4ba1-b755-a748b0c00099" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccruedExpenses" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccruedExpenses"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccruedExpenses" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_1ee05ee4-923f-40db-90a7-a6af49a949f2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_9bf2ccfb-9587-4bee-95b8-00d198c258db" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_1ee05ee4-923f-40db-90a7-a6af49a949f2" xlink:to="loc_us-gaap_AccountsPayableAndAccruedLiabilitiesDisclosureTextBlock_9bf2ccfb-9587-4bee-95b8-00d198c258db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/Leases" xlink:type="simple" xlink:href="cfms-20230331.xsd#Leases"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/Leases" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_05c9b9e6-d615-485c-9d67-3b32cb88c4fa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeasesTextBlock_c17bc0c3-ffa8-478c-b153-07ee890a0681" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeasesTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_05c9b9e6-d615-485c-9d67-3b32cb88c4fa" xlink:to="loc_us-gaap_LesseeOperatingLeasesTextBlock_c17bc0c3-ffa8-478c-b153-07ee890a0681" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/CommitmentsandContingencies" xlink:type="simple" xlink:href="cfms-20230331.xsd#CommitmentsandContingencies"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/CommitmentsandContingencies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_c4c245ce-c802-436f-9ed9-b359870e38ac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_fbc059bf-e625-4bd9-8929-ea39e949f6a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_c4c245ce-c802-436f-9ed9-b359870e38ac" xlink:to="loc_us-gaap_CommitmentsAndContingenciesDisclosureTextBlock_fbc059bf-e625-4bd9-8929-ea39e949f6a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/DebtandNotesPayable" xlink:type="simple" xlink:href="cfms-20230331.xsd#DebtandNotesPayable"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/DebtandNotesPayable" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_93cfffb0-b76d-4310-817e-2a99c001cb22" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebtTextBlock_11a36691-a354-47f8-a728-82a475c00549" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebtTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_93cfffb0-b76d-4310-817e-2a99c001cb22" xlink:to="loc_us-gaap_LongTermDebtTextBlock_11a36691-a354-47f8-a728-82a475c00549" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquity" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquity"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquity" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_ca165afd-7155-41b4-bed9-fef33ec9e783" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareholdersEquityAndShareBasedPaymentsTextBlock_e2fd59d6-b1ea-4ef4-b848-c955973678dd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareholdersEquityAndShareBasedPaymentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_ca165afd-7155-41b4-bed9-fef33ec9e783" xlink:to="loc_us-gaap_ShareholdersEquityAndShareBasedPaymentsTextBlock_e2fd59d6-b1ea-4ef4-b848-c955973678dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SegmentandGeographicData" xlink:type="simple" xlink:href="cfms-20230331.xsd#SegmentandGeographicData"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SegmentandGeographicData" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_1173cde1-42de-487b-bb90-bfded3a982cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingDisclosureTextBlock_b7c29c01-8107-48f3-8a41-e17747a6b598" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingDisclosureTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_1173cde1-42de-487b-bb90-bfded3a982cb" xlink:to="loc_us-gaap_SegmentReportingDisclosureTextBlock_b7c29c01-8107-48f3-8a41-e17747a6b598" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesPolicies"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesPolicies" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UseOfEstimates_a7ef4ae2-5a7d-46dd-abbb-edad5a587df7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UseOfEstimates"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_UseOfEstimates_a7ef4ae2-5a7d-46dd-abbb-edad5a587df7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ConcentrationRiskPolicyTextBlock_7296723a-81d7-48d5-a0bd-62a6eaa74f6b" xlink:href="cfms-20230331.xsd#cfms_ConcentrationRiskPolicyTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_cfms_ConcentrationRiskPolicyTextBlock_7296723a-81d7-48d5-a0bd-62a6eaa74f6b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ConsolidationPolicyTextBlock_bf2e2456-7827-430f-9639-3f44987da2d5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ConsolidationPolicyTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_ConsolidationPolicyTextBlock_bf2e2456-7827-430f-9639-3f44987da2d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_0b680cbe-18f9-4279-9986-d5245f3e8748" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_CashAndCashEquivalentsRestrictedCashAndCashEquivalentsPolicy_0b680cbe-18f9-4279-9986-d5245f3e8748" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_dc43d3e6-64a5-49a1-ae51-1afa84f24b21" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FairValueMeasurementPolicyPolicyTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_FairValueMeasurementPolicyPolicyTextBlock_dc43d3e6-64a5-49a1-ae51-1afa84f24b21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_3b31cc03-6c6d-45a6-91ba-9c92cffcedfd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TradeAndOtherAccountsReceivablePolicy"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_TradeAndOtherAccountsReceivablePolicy_3b31cc03-6c6d-45a6-91ba-9c92cffcedfd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryPolicyTextBlock_12d61525-e453-4d33-bddd-4c88f42e04a5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryPolicyTextBlock"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_InventoryPolicyTextBlock_12d61525-e453-4d33-bddd-4c88f42e04a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_5dc20a5e-c095-427a-a7a2-a1e022f3f50d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentPolicyTextBlock"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentPolicyTextBlock_5dc20a5e-c095-427a-a7a2-a1e022f3f50d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy_33ec6900-907c-4a67-888a-69f2ad89fb18" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_GoodwillAndIntangibleAssetsIntangibleAssetsPolicy_33ec6900-907c-4a67-888a-69f2ad89fb18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeasesPolicyTextBlock_67631bfe-c568-4719-82a9-0feaca815f7d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeasesPolicyTextBlock"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_LesseeLeasesPolicyTextBlock_67631bfe-c568-4719-82a9-0feaca815f7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_48fa5e96-b173-408a-89a5-c0db6052451f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerPolicyTextBlock"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerPolicyTextBlock_48fa5e96-b173-408a-89a5-c0db6052451f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_de7ac0fc-3e29-48b1-bc52-6ce72b091fdf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpensePolicy"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpensePolicy_de7ac0fc-3e29-48b1-bc52-6ce72b091fdf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdvertisingCostsPolicyTextBlock_9029c7aa-b553-457a-a3e6-2c908722aae4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdvertisingCostsPolicyTextBlock"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_AdvertisingCostsPolicyTextBlock_9029c7aa-b553-457a-a3e6-2c908722aae4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_f2b7d4be-d194-4279-b9e4-5bee901cd9cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingPolicyPolicyTextBlock"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_SegmentReportingPolicyPolicyTextBlock_f2b7d4be-d194-4279-b9e4-5bee901cd9cb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_cfd703a7-04a5-46a7-9b63-5f4f63b2b7e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_ForeignCurrencyTransactionsAndTranslationsPolicyTextBlock_cfd703a7-04a5-46a7-9b63-5f4f63b2b7e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxPolicyTextBlock_4261e076-b4e9-4cb4-a256-2bbb9b68a7f8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxPolicyTextBlock"/>
    <link:presentationArc order="16" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_IncomeTaxPolicyTextBlock_4261e076-b4e9-4cb4-a256-2bbb9b68a7f8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_93c7b98d-6804-421f-90a5-abf31513606a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy"/>
    <link:presentationArc order="17" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_ShareBasedCompensationOptionAndIncentivePlansPolicy_93c7b98d-6804-421f-90a5-abf31513606a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerSharePolicyTextBlock_46340ede-b319-4cb6-a099-917045652154" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerSharePolicyTextBlock"/>
    <link:presentationArc order="18" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_EarningsPerSharePolicyTextBlock_46340ede-b319-4cb6-a099-917045652154" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_60661dcb-ef1f-402b-9565-1d15d0434f59" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock"/>
    <link:presentationArc order="19" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_92b6e63f-de87-4388-ade5-373a61108791" xlink:to="loc_us-gaap_NewAccountingPronouncementsPolicyPolicyTextBlock_60661dcb-ef1f-402b-9565-1d15d0434f59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_3e41e0d1-590a-4002-a328-cdec6debb455" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:to="loc_us-gaap_ScheduleOfCashAndCashEquivalentsTableTextBlock_3e41e0d1-590a-4002-a328-cdec6debb455" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_dd1101ff-19d4-4d5b-923e-168c55fa3e40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:to="loc_us-gaap_ScheduleOfRestrictedCashAndCashEquivalentsTextBlock_dd1101ff-19d4-4d5b-923e-168c55fa3e40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_72b1d82c-a740-4b7e-95fa-d7e4e7dc1be6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:to="loc_us-gaap_ContractWithCustomerAssetAndLiabilityTableTextBlock_72b1d82c-a740-4b7e-95fa-d7e4e7dc1be6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_cbcd64f1-4ffd-4241-83dd-ce2145b4490e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:to="loc_us-gaap_ScheduleOfEarningsPerShareBasicAndDilutedTableTextBlock_cbcd64f1-4ffd-4241-83dd-ce2145b4490e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_5ac718ac-7ea1-447a-a134-6c1a9892b116" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_90f99090-ffe7-4367-97c0-5930ab8b9fe5" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTextBlock_5ac718ac-7ea1-447a-a134-6c1a9892b116" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccountsReceivableTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccountsReceivableTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccountsReceivableTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrentAbstract_c8091e68-ff17-44a5-b277-5c5300f06494" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_e91ff285-f77d-4455-8d5f-8eff7698f43b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_c8091e68-ff17-44a5-b277-5c5300f06494" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTextBlock_e91ff285-f77d-4455-8d5f-8eff7698f43b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/InventoriesTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#InventoriesTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/InventoriesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_6e97b8c1-963e-4c8e-ab17-18519e632df8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_96a0e6f4-baa5-4b3f-943d-ffd096697b87" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfInventoryCurrentTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_6e97b8c1-963e-4c8e-ab17-18519e632df8" xlink:to="loc_us-gaap_ScheduleOfInventoryCurrentTableTextBlock_96a0e6f4-baa5-4b3f-943d-ffd096697b87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/PropertyandEquipmentTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#PropertyandEquipmentTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/PropertyandEquipmentTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_385b17c2-6343-4f51-9bc3-142084932fae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_35945a99-c9ff-4262-a6e0-784965892c05" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_385b17c2-6343-4f51-9bc3-142084932fae" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTextBlock_35945a99-c9ff-4262-a6e0-784965892c05" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccruedExpensesTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccruedExpensesTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccruedExpensesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_671a5fc0-2334-4220-aeed-7edb51bfff1d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_3e2d82de-875b-4a95-be35-29fef2e26c09" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_671a5fc0-2334-4220-aeed-7edb51bfff1d" xlink:to="loc_us-gaap_ScheduleOfAccruedLiabilitiesTableTextBlock_3e2d82de-875b-4a95-be35-29fef2e26c09" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/LeasesTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#LeasesTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/LeasesTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_f8c70631-90ad-4f53-a867-29459594b9b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCostTableTextBlock_bbada3ef-1381-486a-8388-0c188f5f0f46" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseCostTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_f8c70631-90ad-4f53-a867-29459594b9b7" xlink:to="loc_us-gaap_LeaseCostTableTextBlock_bbada3ef-1381-486a-8388-0c188f5f0f46" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_17d1d449-a8a5-4acd-b7c1-f0028a8d3989" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_f8c70631-90ad-4f53-a867-29459594b9b7" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityMaturityTableTextBlock_17d1d449-a8a5-4acd-b7c1-f0028a8d3989" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/DebtandNotesPayableTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#DebtandNotesPayableTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/DebtandNotesPayableTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_e01ce415-df1e-4a8f-982d-d64ab20792e5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_4b7966df-3b31-4471-9455-3b2ec33fc7cd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfDebtInstrumentsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_e01ce415-df1e-4a8f-982d-d64ab20792e5" xlink:to="loc_us-gaap_ScheduleOfDebtInstrumentsTextBlock_4b7966df-3b31-4471-9455-3b2ec33fc7cd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_25a43248-ab24-4aea-9497-8ac3e5bd82d6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_e01ce415-df1e-4a8f-982d-d64ab20792e5" xlink:to="loc_us-gaap_ScheduleOfMaturitiesOfLongTermDebtTableTextBlock_25a43248-ab24-4aea-9497-8ac3e5bd82d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_adcce29d-7a88-498e-8cd9-ea039435e94e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:to="loc_us-gaap_ScheduleOfStockholdersEquityNoteWarrantsOrRightsTextBlock_adcce29d-7a88-498e-8cd9-ea039435e94e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_7601b9ef-82c6-4641-93b9-1bc1d0761fac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationStockOptionsActivityTableTextBlock_7601b9ef-82c6-4641-93b9-1bc1d0761fac" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock_7263ff83-72ff-48c6-b384-8eb690826474" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:to="loc_us-gaap_NonvestedRestrictedStockSharesActivityTableTextBlock_7263ff83-72ff-48c6-b384-8eb690826474" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_6f87e8a6-82b2-4387-ac77-8df97313536f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:to="loc_us-gaap_ScheduleOfShareBasedPaymentAwardStockOptionsValuationAssumptionsTableTextBlock_6f87e8a6-82b2-4387-ac77-8df97313536f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_7aa85c72-0d82-41d3-a017-ecf01ee9a3ee" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0071ed26-d9f1-4b5d-82d0-7dbf634cd9c1" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTextBlock_7aa85c72-0d82-41d3-a017-ecf01ee9a3ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SegmentandGeographicDataTables" xlink:type="simple" xlink:href="cfms-20230331.xsd#SegmentandGeographicDataTables"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SegmentandGeographicDataTables" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_f494467a-b704-42aa-bc05-81bd902e6287" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromExternalCustomersByGeographicAreasTableTextBlock_d143672c-8621-4da4-876c-99acdd2da2c4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromExternalCustomersByGeographicAreasTableTextBlock"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_f494467a-b704-42aa-bc05-81bd902e6287" xlink:to="loc_us-gaap_RevenueFromExternalCustomersByGeographicAreasTableTextBlock_d143672c-8621-4da4-876c-99acdd2da2c4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongLivedAssetsByGeographicAreasTableTextBlock_a1c8d6e0-190a-4b58-91b2-fa80319e982d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongLivedAssetsByGeographicAreasTableTextBlock"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_f494467a-b704-42aa-bc05-81bd902e6287" xlink:to="loc_us-gaap_LongLivedAssetsByGeographicAreasTableTextBlock_a1c8d6e0-190a-4b58-91b2-fa80319e982d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/OrganizationandBasisofPresentationDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#OrganizationandBasisofPresentationDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/OrganizationandBasisofPresentationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_aedb49ad-d96c-4d43-9c82-8a69f80e1f67" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OrganizationConsolidationAndPresentationOfFinancialStatementsAbstract_aedb49ad-d96c-4d43-9c82-8a69f80e1f67" xlink:to="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_db99639f-5c14-4f63-8687-d4fe7e68d0ff" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:to="loc_us-gaap_CreditFacilityAxis_db99639f-5c14-4f63-8687-d4fe7e68d0ff" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_09021739-0e24-49c0-b2b8-a50d87ae4455" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_db99639f-5c14-4f63-8687-d4fe7e68d0ff" xlink:to="loc_us-gaap_CreditFacilityDomain_09021739-0e24-49c0-b2b8-a50d87ae4455" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_TermLoanMember_bccac171-4569-4309-b9b9-d49e4d0db7e5" xlink:href="cfms-20230331.xsd#cfms_TermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_09021739-0e24-49c0-b2b8-a50d87ae4455" xlink:to="loc_cfms_TermLoanMember_bccac171-4569-4309-b9b9-d49e4d0db7e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_65c9e7cd-c216-4293-8c8c-6aa111433f0a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:to="loc_us-gaap_DebtInstrumentAxis_65c9e7cd-c216-4293-8c8c-6aa111433f0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_de45c1c1-79e3-494c-bfca-91bec689091d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_65c9e7cd-c216-4293-8c8c-6aa111433f0a" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_de45c1c1-79e3-494c-bfca-91bec689091d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MidCapFinancialServicesLLCTermLoanMember_363ccbd7-d0f3-45ec-9410-dd8409e8b558" xlink:href="cfms-20230331.xsd#cfms_MidCapFinancialServicesLLCTermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_de45c1c1-79e3-494c-bfca-91bec689091d" xlink:to="loc_cfms_MidCapFinancialServicesLLCTermLoanMember_363ccbd7-d0f3-45ec-9410-dd8409e8b558" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_f53585b3-4c9d-4c50-ae88-43dd25c67091" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_f53585b3-4c9d-4c50-ae88-43dd25c67091" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_98b0c0f6-afd3-4aea-ad71-3d8da6236718" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityLenderDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_f53585b3-4c9d-4c50-ae88-43dd25c67091" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_98b0c0f6-afd3-4aea-ad71-3d8da6236718" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MidCapFinancialServicesLLCMember_5aec1b9d-4e3f-4193-a80d-f9330ab3ccdb" xlink:href="cfms-20230331.xsd#cfms_MidCapFinancialServicesLLCMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_98b0c0f6-afd3-4aea-ad71-3d8da6236718" xlink:to="loc_cfms_MidCapFinancialServicesLLCMember_5aec1b9d-4e3f-4193-a80d-f9330ab3ccdb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityTable_47f8f347-885d-4905-87ca-a2cc396ab803" xlink:to="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RetainedEarningsAccumulatedDeficit_91c2e24e-a903-47e7-8722-f9ef96c86aa7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RetainedEarningsAccumulatedDeficit"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_RetainedEarningsAccumulatedDeficit_91c2e24e-a903-47e7-8722-f9ef96c86aa7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_dc515d52-2505-4163-8ed9-6d2caad04e2b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsAndShortTermInvestments"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_CashCashEquivalentsAndShortTermInvestments_dc515d52-2505-4163-8ed9-6d2caad04e2b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_e9953c22-2e89-477b-82e9-61725f278da3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_e9953c22-2e89-477b-82e9-61725f278da3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_aa2890c0-bee8-43fb-a95d-e4339237ee21" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_aa2890c0-bee8-43fb-a95d-e4339237ee21" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_f7c0edde-60a5-4f3c-904c-a41de9c62698" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_f7c0edde-60a5-4f3c-904c-a41de9c62698" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTerm_f370cab9-6703-4ad5-825b-7db0732f581c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentTerm"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_DebtInstrumentTerm_f370cab9-6703-4ad5-825b-7db0732f581c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_e0ee9578-8012-431f-b170-a91c65bc7ed7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLineItems_8c3934b1-17af-4d0d-a49d-4313d86204c7" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_e0ee9578-8012-431f-b170-a91c65bc7ed7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_d70be7be-5d4a-4456-ac13-647e1304a93e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_d70be7be-5d4a-4456-ac13-647e1304a93e" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_dc8b44ac-997a-4ff2-9f48-804cd5a85297" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:to="loc_srt_RangeAxis_dc8b44ac-997a-4ff2-9f48-804cd5a85297" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9d51a322-d863-4881-8608-2490ddd1e9ce" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_dc8b44ac-997a-4ff2-9f48-804cd5a85297" xlink:to="loc_srt_RangeMember_9d51a322-d863-4881-8608-2490ddd1e9ce" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_ac1622bb-67c3-425a-af37-c3f156a47516" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9d51a322-d863-4881-8608-2490ddd1e9ce" xlink:to="loc_srt_MinimumMember_ac1622bb-67c3-425a-af37-c3f156a47516" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_9d95858d-d305-4c4d-be2d-a18377e6651a" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9d51a322-d863-4881-8608-2490ddd1e9ce" xlink:to="loc_srt_MaximumMember_9d95858d-d305-4c4d-be2d-a18377e6651a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_CounterpartyNameAxis_a89130f6-ff92-4ae2-b42f-28bcdd561f37" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_CounterpartyNameAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:to="loc_srt_CounterpartyNameAxis_a89130f6-ff92-4ae2-b42f-28bcdd561f37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RepurchaseAgreementCounterpartyNameDomain_2edd12e8-2461-4852-8396-22e7432f0c14" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RepurchaseAgreementCounterpartyNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_CounterpartyNameAxis_a89130f6-ff92-4ae2-b42f-28bcdd561f37" xlink:to="loc_srt_RepurchaseAgreementCounterpartyNameDomain_2edd12e8-2461-4852-8396-22e7432f0c14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_Paragon28IncMember_db7ff811-8b8d-4440-8697-e942221e9569" xlink:href="cfms-20230331.xsd#cfms_Paragon28IncMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RepurchaseAgreementCounterpartyNameDomain_2edd12e8-2461-4852-8396-22e7432f0c14" xlink:to="loc_cfms_Paragon28IncMember_db7ff811-8b8d-4440-8697-e942221e9569" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_ff1cf22f-5d04-4f12-9cbf-1ab19deda1e5" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:to="loc_srt_ProductOrServiceAxis_ff1cf22f-5d04-4f12-9cbf-1ab19deda1e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_63245a39-a06d-44eb-81d3-2d9b22e14841" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_ff1cf22f-5d04-4f12-9cbf-1ab19deda1e5" xlink:to="loc_srt_ProductsAndServicesDomain_63245a39-a06d-44eb-81d3-2d9b22e14841" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShippingAndHandlingMember_134501d2-3920-4d1d-af44-32a79b650b52" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShippingAndHandlingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_63245a39-a06d-44eb-81d3-2d9b22e14841" xlink:to="loc_us-gaap_ShippingAndHandlingMember_134501d2-3920-4d1d-af44-32a79b650b52" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleTable_1bc5c41a-3ca9-45a6-850a-1c075a06f3b4" xlink:to="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_CashAndCashEquivalentsHeldInForeignBankAccounts_45178512-b688-4df5-aa61-10f33c529bb8" xlink:href="cfms-20230331.xsd#cfms_CashAndCashEquivalentsHeldInForeignBankAccounts"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_cfms_CashAndCashEquivalentsHeldInForeignBankAccounts_45178512-b688-4df5-aa61-10f33c529bb8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_a89bea49-0353-43b7-b3fa-9cd9af8e1b66" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_a89bea49-0353-43b7-b3fa-9cd9af8e1b66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryAdjustments_607b539c-be79-4380-8566-4fee5208231f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryAdjustments"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_InventoryAdjustments_607b539c-be79-4380-8566-4fee5208231f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_b16c9729-49ce-4b61-a787-f80b7b741a6f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_b16c9729-49ce-4b61-a787-f80b7b741a6f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ContractwithCustomerPaymentPeriod_4e8d05ef-b012-4d2f-9a52-5382b0d5d685" xlink:href="cfms-20230331.xsd#cfms_ContractwithCustomerPaymentPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_cfms_ContractwithCustomerPaymentPeriod_4e8d05ef-b012-4d2f-9a52-5382b0d5d685" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerLiabilityCurrent_77fad53d-04e0-4eed-a304-c9ed66652dbe" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerLiabilityCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_ContractWithCustomerLiabilityCurrent_77fad53d-04e0-4eed-a304-c9ed66652dbe" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerAssetPurchase_33c1bef0-d083-4489-83f4-a250bd4e7b9d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerAssetPurchase"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_ContractWithCustomerAssetPurchase_33c1bef0-d083-4489-83f4-a250bd4e7b9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LicenseAgreementMilestonePayment_09f6694e-ff60-45ff-9a93-090c9506be0c" xlink:href="cfms-20230331.xsd#cfms_LicenseAgreementMilestonePayment"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_cfms_LicenseAgreementMilestonePayment_09f6694e-ff60-45ff-9a93-090c9506be0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LicenseAgreementPotentialMilestonePayment_0bd7ea98-b633-4775-bf0c-34d65723a4ae" xlink:href="cfms-20230331.xsd#cfms_LicenseAgreementPotentialMilestonePayment"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_cfms_LicenseAgreementPotentialMilestonePayment_0bd7ea98-b633-4775-bf0c-34d65723a4ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LicenseAgreementRoyaltyAndLicenseRevenue_dc24da3a-9bb0-4831-b821-1eb7feed5971" xlink:href="cfms-20230331.xsd#cfms_LicenseAgreementRoyaltyAndLicenseRevenue"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_cfms_LicenseAgreementRoyaltyAndLicenseRevenue_dc24da3a-9bb0-4831-b821-1eb7feed5971" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfGoodsAndServicesSold_be1d451e-f0f9-4717-8cf6-9776aaf9b29c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfGoodsAndServicesSold"/>
    <link:presentationArc order="11" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_CostOfGoodsAndServicesSold_be1d451e-f0f9-4717-8cf6-9776aaf9b29c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AdvertisingExpense_8605e77e-0401-41b5-83ab-6bcf673d348a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AdvertisingExpense"/>
    <link:presentationArc order="12" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_AdvertisingExpense_8605e77e-0401-41b5-83ab-6bcf673d348a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfOperatingSegments_7a651cef-c085-47b8-8bfe-311a2292f850" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NumberOfOperatingSegments"/>
    <link:presentationArc order="13" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_NumberOfOperatingSegments_7a651cef-c085-47b8-8bfe-311a2292f850" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_01711011-7e4e-46b0-aff7-2af15c88254a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CurrentIncomeTaxExpenseBenefit"/>
    <link:presentationArc order="14" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_CurrentIncomeTaxExpenseBenefit_01711011-7e4e-46b0-aff7-2af15c88254a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued_0d1b5003-808f-45e2-a365-83d9778ba098" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued"/>
    <link:presentationArc order="15" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NewAccountingPronouncementsOrChangeInAccountingPrincipleLineItems_7275f83a-025c-4052-b8ae-71264132e850" xlink:to="loc_us-gaap_IncomeTaxExaminationPenaltiesAndInterestAccrued_0d1b5003-808f-45e2-a365-83d9778ba098" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesCashCashEquivalentsandRestrictedCashDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesCashCashEquivalentsandRestrictedCashDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesCashCashEquivalentsandRestrictedCashDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_4225b3ae-a90a-4b81-8c33-b9afb2b4804c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_4ca14134-9ad6-4888-ab31-e94429a6d4c0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashAndCashEquivalentsAtCarryingValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4225b3ae-a90a-4b81-8c33-b9afb2b4804c" xlink:to="loc_us-gaap_CashAndCashEquivalentsAtCarryingValue_4ca14134-9ad6-4888-ab31-e94429a6d4c0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedCashAndCashEquivalents_ed8c8a4d-e191-4e9f-a995-e29ec5f4427b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedCashAndCashEquivalents"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4225b3ae-a90a-4b81-8c33-b9afb2b4804c" xlink:to="loc_us-gaap_RestrictedCashAndCashEquivalents_ed8c8a4d-e191-4e9f-a995-e29ec5f4427b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/netLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5be131be-0b61-473c-b998-d46af9207a7a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_4225b3ae-a90a-4b81-8c33-b9afb2b4804c" xlink:to="loc_us-gaap_CashCashEquivalentsRestrictedCashAndRestrictedCashEquivalents_5be131be-0b61-473c-b998-d46af9207a7a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesRebateReserveDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesRebateReserveDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesRebateReserveDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_7250e9d3-5391-4aa6-bc8a-4fc4a66217b5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:href="cfms-20230331.xsd#cfms_ChangeinContractwithCustomerLiabilityRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_7250e9d3-5391-4aa6-bc8a-4fc4a66217b5" xlink:to="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerRefundLiability_4b3f3ee1-15e5-4035-b3e6-fa865be00d22" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerRefundLiability"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:to="loc_us-gaap_ContractWithCustomerRefundLiability_4b3f3ee1-15e5-4035-b3e6-fa865be00d22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ContractWithCustomerLiabilityNewContractAdditions_078e11ed-8268-4486-90be-cfc631b75b87" xlink:href="cfms-20230331.xsd#cfms_ContractWithCustomerLiabilityNewContractAdditions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:to="loc_cfms_ContractWithCustomerLiabilityNewContractAdditions_078e11ed-8268-4486-90be-cfc631b75b87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ContractWithCustomerRefundLiabilityPaymentsOrCreditsIssued_f143cf27-2622-4f1b-8023-c3898de3875d" xlink:href="cfms-20230331.xsd#cfms_ContractWithCustomerRefundLiabilityPaymentsOrCreditsIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:to="loc_cfms_ContractWithCustomerRefundLiabilityPaymentsOrCreditsIssued_f143cf27-2622-4f1b-8023-c3898de3875d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ContractWithCustomerRefundLiability_d5060f28-445d-4dcd-8f0e-9b5df25953bf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ContractWithCustomerRefundLiability"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ChangeinContractwithCustomerLiabilityRollForward_71bcef76-841f-4b72-8515-b26251da8ef5" xlink:to="loc_us-gaap_ContractWithCustomerRefundLiability_d5060f28-445d-4dcd-8f0e-9b5df25953bf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesExpensesandNetLossPerShareDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesExpensesandNetLossPerShareDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesExpensesandNetLossPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDilutedAbstract_b84eae7e-6b69-44fc-9ec7-08daaa7b8afa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDilutedAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDilutedAbstract_b84eae7e-6b69-44fc-9ec7-08daaa7b8afa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_5e2bb25a-ed99-4a5f-a0b1-8e2689915000" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDilutedAbstract_b84eae7e-6b69-44fc-9ec7-08daaa7b8afa" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersBasic_5e2bb25a-ed99-4a5f-a0b1-8e2689915000" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_8cd6cb8d-e149-4f28-a2e0-00a1e00369f5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDilutedAbstract_b84eae7e-6b69-44fc-9ec7-08daaa7b8afa" xlink:to="loc_us-gaap_NetIncomeLossAvailableToCommonStockholdersDiluted_8cd6cb8d-e149-4f28-a2e0-00a1e00369f5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_acf101f4-6c65-4cba-a329-e3bcf5bc3787" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_acf101f4-6c65-4cba-a329-e3bcf5bc3787" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_125e2e40-8fc7-46c0-b329-a6f2aebe2a7d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfSharesOutstandingBasic"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_acf101f4-6c65-4cba-a329-e3bcf5bc3787" xlink:to="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingBasic_125e2e40-8fc7-46c0-b329-a6f2aebe2a7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_c9197e61-c219-4eb9-97ab-bf71ac4dc9d5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_WeightedAverageNumberOfSharesOutstandingDilutedDisclosureItemsAbstract_acf101f4-6c65-4cba-a329-e3bcf5bc3787" xlink:to="loc_us-gaap_WeightedAverageNumberOfDilutedSharesOutstanding_c9197e61-c219-4eb9-97ab-bf71ac4dc9d5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareBasic_15585e53-b0e7-4ac1-b285-63fbc4c9a891" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareBasic"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:to="loc_us-gaap_EarningsPerShareBasic_15585e53-b0e7-4ac1-b285-63fbc4c9a891" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EarningsPerShareDiluted_00caf212-6018-49a0-a60b-bf6e081b20a9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EarningsPerShareDiluted"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:to="loc_us-gaap_EarningsPerShareDiluted_00caf212-6018-49a0-a60b-bf6e081b20a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_a0616bdb-f80b-402f-b987-4bba43f1b075" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_b17413df-609a-419f-895a-09aa973010b8" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_a0616bdb-f80b-402f-b987-4bba43f1b075" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedfromComputationofEarningsPerShareDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedfromComputationofEarningsPerShareDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SummaryofSignificantAccountingPoliciesAntidilutiveSecuritiesExcludedfromComputationofEarningsPerShareDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountingPoliciesAbstract_bc126e38-0c5d-4797-bedc-3efddb6b233c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountingPoliciesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_b7c00ca5-c7ca-42fc-8c88-fd2cc8a4ed38" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountingPoliciesAbstract_bc126e38-0c5d-4797-bedc-3efddb6b233c" xlink:to="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_b7c00ca5-c7ca-42fc-8c88-fd2cc8a4ed38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_df8c8098-6c7b-4941-9ad2-0e76600b200e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_b7c00ca5-c7ca-42fc-8c88-fd2cc8a4ed38" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_df8c8098-6c7b-4941-9ad2-0e76600b200e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesNameDomain_f83636c4-c000-4f2d-a3e4-5433c086d466" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareByAntidilutiveSecuritiesAxis_df8c8098-6c7b-4941-9ad2-0e76600b200e" xlink:to="loc_us-gaap_AntidilutiveSecuritiesNameDomain_f83636c4-c000-4f2d-a3e4-5433c086d466" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockOptionMember_47df1343-5aef-4b45-9054-b88d0c3ef8d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockOptionMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesNameDomain_f83636c4-c000-4f2d-a3e4-5433c086d466" xlink:to="loc_us-gaap_StockOptionMember_47df1343-5aef-4b45-9054-b88d0c3ef8d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_6bb96c3b-ac49-473a-b204-5595184219e8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareTable_b7c00ca5-c7ca-42fc-8c88-fd2cc8a4ed38" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_6bb96c3b-ac49-473a-b204-5595184219e8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_0cef091d-9aed-4f3d-ac7c-8a0bfe293c84" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_6bb96c3b-ac49-473a-b204-5595184219e8" xlink:to="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareAmount_0cef091d-9aed-4f3d-ac7c-8a0bfe293c84" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_863f1a08-506b-40ee-be9b-8c2a48d917cf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AntidilutiveSecuritiesExcludedFromComputationOfEarningsPerShareLineItems_6bb96c3b-ac49-473a-b204-5595184219e8" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_863f1a08-506b-40ee-be9b-8c2a48d917cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccountsReceivableScheduleofAccountsReceivableDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccountsReceivableScheduleofAccountsReceivableDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccountsReceivableScheduleofAccountsReceivableDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrentAbstract_7ea019a7-14b4-4cd0-849e-26d265460f87" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableGrossCurrent_3b583c9d-a629-48fb-aa0f-783d3d32b65e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableGrossCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_7ea019a7-14b4-4cd0-849e-26d265460f87" xlink:to="loc_us-gaap_AccountsReceivableGrossCurrent_3b583c9d-a629-48fb-aa0f-783d3d32b65e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_2eafec13-30d7-4721-9e02-08ff4f2b0275" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_7ea019a7-14b4-4cd0-849e-26d265460f87" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableCurrent_2eafec13-30d7-4721-9e02-08ff4f2b0275" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_e4763c33-bb12-42bf-aa9f-2fc67be4b720" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_7ea019a7-14b4-4cd0-849e-26d265460f87" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_e4763c33-bb12-42bf-aa9f-2fc67be4b720" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccountsReceivableNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccountsReceivableNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccountsReceivableNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivablesAbstract_63256a94-98a7-458e-8169-eafbc9f39800" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ReceivablesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrent_c2c52aa7-2013-49b0-b18d-5bc5abcb7c1f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_63256a94-98a7-458e-8169-eafbc9f39800" xlink:to="loc_us-gaap_AccountsReceivableNetCurrent_c2c52aa7-2013-49b0-b18d-5bc5abcb7c1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_UnbilledContractsReceivable_2371c9f1-c205-4b84-99ec-76d17643dcd1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_UnbilledContractsReceivable"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_63256a94-98a7-458e-8169-eafbc9f39800" xlink:to="loc_us-gaap_UnbilledContractsReceivable_2371c9f1-c205-4b84-99ec-76d17643dcd1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_7fcf3fea-6f9a-4253-9e54-3e9f158567ad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivablesAbstract_63256a94-98a7-458e-8169-eafbc9f39800" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_7fcf3fea-6f9a-4253-9e54-3e9f158567ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccountsReceivableAllowanceforCreditLossesandReturnsDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccountsReceivableAllowanceforCreditLossesandReturnsDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccountsReceivableAllowanceforCreditLossesandReturnsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsReceivableNetCurrentAbstract_9ba99b45-7ca8-4e21-b876-1ccdb67ddaec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsReceivableNetCurrentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_b2767efd-d7f3-4d3f-8c9c-057d99e0de00" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsReceivableNetCurrentAbstract_9ba99b45-7ca8-4e21-b876-1ccdb67ddaec" xlink:to="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_b2767efd-d7f3-4d3f-8c9c-057d99e0de00" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_a423fe2e-a74b-4a7c-9b7e-bffb046e01a4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_b2767efd-d7f3-4d3f-8c9c-057d99e0de00" xlink:to="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_a423fe2e-a74b-4a7c-9b7e-bffb046e01a4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ReceivableTypeDomain_031c6e84-dcc4-48a1-922e-14e27d13e2d9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ReceivableTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesLoansAndFinancingReceivableByReceivableTypeAxis_a423fe2e-a74b-4a7c-9b7e-bffb046e01a4" xlink:to="loc_us-gaap_ReceivableTypeDomain_031c6e84-dcc4-48a1-922e-14e27d13e2d9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_TradeAccountsReceivableMember_137258e6-30df-471c-b32f-9bc9fae8bc0a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_TradeAccountsReceivableMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_031c6e84-dcc4-48a1-922e-14e27d13e2d9" xlink:to="loc_us-gaap_TradeAccountsReceivableMember_137258e6-30df-471c-b32f-9bc9fae8bc0a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_OtherReceivablesMember_d808d7ad-198a-42ad-9647-485ce952a5cf" xlink:href="cfms-20230331.xsd#cfms_OtherReceivablesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ReceivableTypeDomain_031c6e84-dcc4-48a1-922e-14e27d13e2d9" xlink:to="loc_cfms_OtherReceivablesMember_d808d7ad-198a-42ad-9647-485ce952a5cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_165b014e-7c24-4e65-85d7-e80946f2b2fb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccountsNotesAndLoansReceivableLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfAccountsNotesLoansAndFinancingReceivableTable_b2767efd-d7f3-4d3f-8c9c-057d99e0de00" xlink:to="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_165b014e-7c24-4e65-85d7-e80946f2b2fb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccountsNotesAndLoansReceivableLineItems_165b014e-7c24-4e65-85d7-e80946f2b2fb" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_e2066e2a-1267-4bbb-9e13-ed84dbef4ee1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_e2066e2a-1267-4bbb-9e13-ed84dbef4ee1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivablePeriodIncreaseDecrease_72cd3a6b-801b-4fff-b343-43fc2eeba6c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivablePeriodIncreaseDecrease"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivablePeriodIncreaseDecrease_72cd3a6b-801b-4fff-b343-43fc2eeba6c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_AllowanceforDoubtfulAccountsReceivableOtherAllowances_23d8aa9e-dc55-4d84-81e7-0914f608ef95" xlink:href="cfms-20230331.xsd#cfms_AllowanceforDoubtfulAccountsReceivableOtherAllowances"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:to="loc_cfms_AllowanceforDoubtfulAccountsReceivableOtherAllowances_23d8aa9e-dc55-4d84-81e7-0914f608ef95" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_3f52d083-ef7b-4585-98b5-e84110a8738a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableWriteOffs_3f52d083-ef7b-4585-98b5-e84110a8738a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_9e500867-d131-43b1-8347-df4d0bcd0d74" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllowanceForDoubtfulAccountsReceivable"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AllowanceForDoubtfulAccountsReceivableRollforward_621d79ac-20c7-4a4e-956c-92db93c63492" xlink:to="loc_us-gaap_AllowanceForDoubtfulAccountsReceivable_9e500867-d131-43b1-8347-df4d0bcd0d74" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedPeriodEndLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/InventoriesDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#InventoriesDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/InventoriesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryDisclosureAbstract_70ec1475-7663-4eca-b9e4-5cf547a0af7e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryRawMaterialsNetOfReserves_cbcd51e7-4c89-47c3-b436-1a79ca3b69ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryRawMaterialsNetOfReserves"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_70ec1475-7663-4eca-b9e4-5cf547a0af7e" xlink:to="loc_us-gaap_InventoryRawMaterialsNetOfReserves_cbcd51e7-4c89-47c3-b436-1a79ca3b69ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryWorkInProcessNetOfReserves_9a07b934-2acf-4964-9383-80dc7ca94740" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryWorkInProcessNetOfReserves"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_70ec1475-7663-4eca-b9e4-5cf547a0af7e" xlink:to="loc_us-gaap_InventoryWorkInProcessNetOfReserves_9a07b934-2acf-4964-9383-80dc7ca94740" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_60f765ec-05a1-4659-99da-829c7fc16fe5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryFinishedGoodsNetOfReserves"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_70ec1475-7663-4eca-b9e4-5cf547a0af7e" xlink:to="loc_us-gaap_InventoryFinishedGoodsNetOfReserves_60f765ec-05a1-4659-99da-829c7fc16fe5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_InventoryNet_4052b3f6-8484-4970-b760-3856263e351c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_InventoryNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_InventoryDisclosureAbstract_70ec1475-7663-4eca-b9e4-5cf547a0af7e" xlink:to="loc_us-gaap_InventoryNet_4052b3f6-8484-4970-b760-3856263e351c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/PropertyandEquipmentDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#PropertyandEquipmentDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/PropertyandEquipmentDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_4f703aa3-d3f3-431e-8771-7c400b8108f4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5d69fe45-d21d-490a-959e-749b15a11c35" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfPropertyPlantAndEquipmentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_4f703aa3-d3f3-431e-8771-7c400b8108f4" xlink:to="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5d69fe45-d21d-490a-959e-749b15a11c35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_c396aded-5e08-4661-9404-2dfe617fc318" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentByTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5d69fe45-d21d-490a-959e-749b15a11c35" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_c396aded-5e08-4661-9404-2dfe617fc318" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentByTypeAxis_c396aded-5e08-4661-9404-2dfe617fc318" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquipmentMember_b0dd77f9-c88d-4be7-b4d3-e43b2e631b66" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquipmentMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_us-gaap_EquipmentMember_b0dd77f9-c88d-4be7-b4d3-e43b2e631b66" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_FurnitureAndFixturesMember_82f27981-0bd9-45ce-89dd-cd19c04819db" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_FurnitureAndFixturesMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_us-gaap_FurnitureAndFixturesMember_82f27981-0bd9-45ce-89dd-cd19c04819db" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ComputerEquipmentAndSoftwareMember_f0ccd0d8-732d-4adf-9006-cbe9e40f3f69" xlink:href="cfms-20230331.xsd#cfms_ComputerEquipmentAndSoftwareMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_cfms_ComputerEquipmentAndSoftwareMember_f0ccd0d8-732d-4adf-9006-cbe9e40f3f69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseholdImprovementsMember_32330515-3d82-4199-9418-ae8adedf2c57" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseholdImprovementsMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_us-gaap_LeaseholdImprovementsMember_32330515-3d82-4199-9418-ae8adedf2c57" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ReusableInstrumentsMember_f88fc0cc-f8fb-4205-92f0-28cc36b76d11" xlink:href="cfms-20230331.xsd#cfms_ReusableInstrumentsMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_cfms_ReusableInstrumentsMember_f88fc0cc-f8fb-4205-92f0-28cc36b76d11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MoldingAndToolingMember_dad05e61-df7b-4f43-88d3-5a607b5c9616" xlink:href="cfms-20230331.xsd#cfms_MoldingAndToolingMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentTypeDomain_880df1a4-1c18-42c8-b561-0d49e866395f" xlink:to="loc_cfms_MoldingAndToolingMember_dad05e61-df7b-4f43-88d3-5a607b5c9616" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_cab8a07c-a517-47d6-aa4a-2012dd3e096d" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5d69fe45-d21d-490a-959e-749b15a11c35" xlink:to="loc_srt_RangeAxis_cab8a07c-a517-47d6-aa4a-2012dd3e096d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_9b32d542-45c4-4922-8d30-3828e965ae94" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_cab8a07c-a517-47d6-aa4a-2012dd3e096d" xlink:to="loc_srt_RangeMember_9b32d542-45c4-4922-8d30-3828e965ae94" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_392f64d7-cdcc-40ae-97c7-79632cf6df7c" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9b32d542-45c4-4922-8d30-3828e965ae94" xlink:to="loc_srt_MinimumMember_392f64d7-cdcc-40ae-97c7-79632cf6df7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_f0e32c88-9772-44cf-9b86-8c98acb31934" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_9b32d542-45c4-4922-8d30-3828e965ae94" xlink:to="loc_srt_MaximumMember_f0e32c88-9772-44cf-9b86-8c98acb31934" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfPropertyPlantAndEquipmentTable_5d69fe45-d21d-490a-959e-749b15a11c35" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_de695a88-f11e-42c1-90b9-9d1b8510cc8f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentUsefulLife"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentUsefulLife_de695a88-f11e-42c1-90b9-9d1b8510cc8f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentGross_1bcce89b-343b-46fb-88ef-b9d0a5a6c5a7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentGross_1bcce89b-343b-46fb-88ef-b9d0a5a6c5a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_5e06281c-787d-4fbc-b5ca-55ae05ed0228" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:to="loc_us-gaap_AccumulatedDepreciationDepletionAndAmortizationPropertyPlantAndEquipment_5e06281c-787d-4fbc-b5ca-55ae05ed0228" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_427b0b66-391a-44df-a691-9bd54aa4f50e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentLineItems_3217c47d-5849-4e14-b860-cdf56b6b4fc9" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_427b0b66-391a-44df-a691-9bd54aa4f50e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/PropertyandEquipmentNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#PropertyandEquipmentNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/PropertyandEquipmentNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentAbstract_74497452-4a7f-4ee2-b027-a15b8ea10603" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_Depreciation_83633723-a7c7-40d4-9dec-aeb09efb2c11" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_Depreciation"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_74497452-4a7f-4ee2-b027-a15b8ea10603" xlink:to="loc_us-gaap_Depreciation_83633723-a7c7-40d4-9dec-aeb09efb2c11" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_82467cfc-16f7-4fd2-a9e7-27f7f8ec8fc1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PropertyPlantAndEquipmentAbstract_74497452-4a7f-4ee2-b027-a15b8ea10603" xlink:to="loc_us-gaap_ImpairmentOfLongLivedAssetsToBeDisposedOf_82467cfc-16f7-4fd2-a9e7-27f7f8ec8fc1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/AccruedExpensesDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#AccruedExpensesDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/AccruedExpensesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_a1985893-058a-4ab7-9261-5a199664659d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeRelatedLiabilitiesCurrent"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_EmployeeRelatedLiabilitiesCurrent_a1985893-058a-4ab7-9261-5a199664659d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LitigationReserveCurrent_cffd1f10-d63e-40a0-aa63-eb16561df5d1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LitigationReserveCurrent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_LitigationReserveCurrent_cffd1f10-d63e-40a0-aa63-eb16561df5d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedMarketingCostsCurrent_baca7938-84ce-473f-ac92-c94c8e796fad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedMarketingCostsCurrent"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_AccruedMarketingCostsCurrent_baca7938-84ce-473f-ac92-c94c8e796fad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_AccruedRevenueShareExpenseCurrent_7564edd9-22a3-43ba-be41-dbe65864b0a6" xlink:href="cfms-20230331.xsd#cfms_AccruedRevenueShareExpenseCurrent"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_cfms_AccruedRevenueShareExpenseCurrent_7564edd9-22a3-43ba-be41-dbe65864b0a6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_AccruedClinicalTrialExpenseCurrent_9de62a7c-84d5-4e6e-b8d0-f5cce27ef379" xlink:href="cfms-20230331.xsd#cfms_AccruedClinicalTrialExpenseCurrent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_cfms_AccruedClinicalTrialExpenseCurrent_9de62a7c-84d5-4e6e-b8d0-f5cce27ef379" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredRevenueCurrent_822e4839-d9ae-4adc-bf98-75e2030b4d5c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredRevenueCurrent"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_DeferredRevenueCurrent_822e4839-d9ae-4adc-bf98-75e2030b4d5c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherAccruedLiabilitiesCurrent_8b2ece4a-8151-4303-9115-9074d0c93562" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherAccruedLiabilitiesCurrent"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_OtherAccruedLiabilitiesCurrent_8b2ece4a-8151-4303-9115-9074d0c93562" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AccruedLiabilitiesCurrent_1c803e49-a354-4934-9ddd-d20d71f398b8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AccruedLiabilitiesCurrent"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AccruedLiabilitiesAndOtherLiabilitiesAbstract_77edcf5c-e9e8-444c-80f5-8eb9d3f519ac" xlink:to="loc_us-gaap_AccruedLiabilitiesCurrent_1c803e49-a354-4934-9ddd-d20d71f398b8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/LeasesNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#LeasesNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/LeasesNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_740e9515-7d1f-4018-9629-b12e9ee389d3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionTable_66757232-7dbb-49dd-816d-de30f3da118f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeaseDescriptionTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_740e9515-7d1f-4018-9629-b12e9ee389d3" xlink:to="loc_us-gaap_LesseeLeaseDescriptionTable_66757232-7dbb-49dd-816d-de30f3da118f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_7989ca97-960b-42e3-b4ae-3f4cf2302d9d" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_66757232-7dbb-49dd-816d-de30f3da118f" xlink:to="loc_srt_RangeAxis_7989ca97-960b-42e3-b4ae-3f4cf2302d9d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_8f5af070-effc-4499-be3e-d2b2a47fc67f" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_7989ca97-960b-42e3-b4ae-3f4cf2302d9d" xlink:to="loc_srt_RangeMember_8f5af070-effc-4499-be3e-d2b2a47fc67f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_888379fa-5eaf-4db3-814a-0df4504d66c6" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_8f5af070-effc-4499-be3e-d2b2a47fc67f" xlink:to="loc_srt_MinimumMember_888379fa-5eaf-4db3-814a-0df4504d66c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_75efa112-5d61-4afe-b401-7f9407d055af" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_8f5af070-effc-4499-be3e-d2b2a47fc67f" xlink:to="loc_srt_MaximumMember_75efa112-5d61-4afe-b401-7f9407d055af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis_a509f5ae-70de-4213-bd7f-43c2405a3f20" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_66757232-7dbb-49dd-816d-de30f3da118f" xlink:to="loc_srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis_a509f5ae-70de-4213-bd7f-43c2405a3f20" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RealEstateAndAccumulatedDepreciationNameOfPropertyDomain_7716fa4b-8c42-4dbe-90bc-93ba1b79b7b9" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RealEstateAndAccumulatedDepreciationNameOfPropertyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RealEstateAndAccumulatedDepreciationDescriptionOfPropertyAxis_a509f5ae-70de-4213-bd7f-43c2405a3f20" xlink:to="loc_srt_RealEstateAndAccumulatedDepreciationNameOfPropertyDomain_7716fa4b-8c42-4dbe-90bc-93ba1b79b7b9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_BillericaFacilityMember_0488033f-9e96-48c5-8cd7-54fa2cadac80" xlink:href="cfms-20230331.xsd#cfms_BillericaFacilityMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RealEstateAndAccumulatedDepreciationNameOfPropertyDomain_7716fa4b-8c42-4dbe-90bc-93ba1b79b7b9" xlink:to="loc_cfms_BillericaFacilityMember_0488033f-9e96-48c5-8cd7-54fa2cadac80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeLeaseDescriptionLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionTable_66757232-7dbb-49dd-816d-de30f3da118f" xlink:to="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRemainingLeaseTerm_896929d6-96e6-4186-bce9-fbf7e1a0c3c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseRemainingLeaseTerm"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:to="loc_us-gaap_LesseeOperatingLeaseRemainingLeaseTerm_896929d6-96e6-4186-bce9-fbf7e1a0c3c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LesseeLeasingArrangementsOperatingLeasesNumberofRenewalOptions_d3b22999-372e-4f9f-8df7-6f9376f73148" xlink:href="cfms-20230331.xsd#cfms_LesseeLeasingArrangementsOperatingLeasesNumberofRenewalOptions"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:to="loc_cfms_LesseeLeasingArrangementsOperatingLeasesNumberofRenewalOptions_d3b22999-372e-4f9f-8df7-6f9376f73148" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_3ba1b476-6c73-4109-9971-d67ef2e7c621" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseRenewalTerm"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:to="loc_us-gaap_LesseeOperatingLeaseRenewalTerm_3ba1b476-6c73-4109-9971-d67ef2e7c621" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_87148659-5618-4321-9be0-346cfe72a3ae" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageRemainingLeaseTerm1_87148659-5618-4321-9be0-346cfe72a3ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_8022e5d3-8628-4ed1-a909-13fdb4e33460" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LesseeLeaseDescriptionLineItems_a85f904f-d14e-437e-9a1b-da11f5a418e5" xlink:to="loc_us-gaap_OperatingLeaseWeightedAverageDiscountRatePercent_8022e5d3-8628-4ed1-a909-13fdb4e33460" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/LeasesLeaseCostDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#LeasesLeaseCostDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/LeasesLeaseCostDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_0a4e34bc-49a6-429b-85ce-33e2872e8440" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseCost_4077aae9-279f-45d2-97bb-361e065916c5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseCost"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0a4e34bc-49a6-429b-85ce-33e2872e8440" xlink:to="loc_us-gaap_OperatingLeaseCost_4077aae9-279f-45d2-97bb-361e065916c5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableLeaseCost_574e1a1a-434f-4bb9-84af-717cf8ff84df" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableLeaseCost"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0a4e34bc-49a6-429b-85ce-33e2872e8440" xlink:to="loc_us-gaap_VariableLeaseCost_574e1a1a-434f-4bb9-84af-717cf8ff84df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeaseCost_93c2232f-c622-48f3-bc11-779c1eed3da6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeaseCost"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_0a4e34bc-49a6-429b-85ce-33e2872e8440" xlink:to="loc_us-gaap_LeaseCost_93c2232f-c622-48f3-bc11-779c1eed3da6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/LeasesScheduleofLeaseMaturitiesDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#LeasesScheduleofLeaseMaturitiesDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/LeasesScheduleofLeaseMaturitiesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LeasesAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_c622618c-81d4-4950-a163-3d7cbef899ef" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsRemainderOfFiscalYear_c622618c-81d4-4950-a163-3d7cbef899ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_6fdba977-d223-4c26-a489-7d703d198bb0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueNextTwelveMonths_6fdba977-d223-4c26-a489-7d703d198bb0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_171cdf9f-2aac-4a69-ad23-1b0f9cca34bc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearTwo_171cdf9f-2aac-4a69-ad23-1b0f9cca34bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_c47d0542-fdf7-4357-8186-b822d25d6344" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearThree_c47d0542-fdf7-4357-8186-b822d25d6344" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_0c345dd9-2bde-4ff4-9215-bae0d45f8188" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDueYearFour_0c345dd9-2bde-4ff4-9215-bae0d45f8188" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0aa4555b-c21f-4ae3-9947-85782ce88951" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityPaymentsDue_0aa4555b-c21f-4ae3-9947-85782ce88951" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_baf42967-0a94-43ba-a61e-35327765b96e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_LesseeOperatingLeaseLiabilityUndiscountedExcessAmount_baf42967-0a94-43ba-a61e-35327765b96e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OperatingLeaseLiability_df9143d3-c615-4d82-8da2-cc3a1b5ecc8d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OperatingLeaseLiability"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LeasesAbstract_dfe36a49-f5cf-4083-a6f2-fb6baad7a11b" xlink:to="loc_us-gaap_OperatingLeaseLiability_df9143d3-c615-4d82-8da2-cc3a1b5ecc8d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/LeasesScheduleofLeaseMaturitiesDetails_1" xlink:type="simple" xlink:href="cfms-20230331.xsd#LeasesScheduleofLeaseMaturitiesDetails_1"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/LeasesScheduleofLeaseMaturitiesDetails_1" xlink:type="extended"/>
  <link:roleRef roleURI="http://www.conformis.com/role/CommitmentsandContingenciesDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#CommitmentsandContingenciesDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/CommitmentsandContingenciesDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f2f07780-5c1b-4b70-96d0-0632e2201cb5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommitmentsAndContingenciesDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CommitmentsAndContingenciesDisclosureAbstract_f2f07780-5c1b-4b70-96d0-0632e2201cb5" xlink:to="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_b82e067c-464e-4d36-abd1-015a1d0c74e6" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:to="loc_srt_RangeAxis_b82e067c-464e-4d36-abd1-015a1d0c74e6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_f2f0a39b-3585-4931-a798-8fdc3b8da6ae" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_b82e067c-464e-4d36-abd1-015a1d0c74e6" xlink:to="loc_srt_RangeMember_f2f0a39b-3585-4931-a798-8fdc3b8da6ae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_6e182d15-1c4f-40ed-95a0-631c99116b7d" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_f2f0a39b-3585-4931-a798-8fdc3b8da6ae" xlink:to="loc_srt_MinimumMember_6e182d15-1c4f-40ed-95a0-631c99116b7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_df24d459-e81f-4444-bb79-a95e57d320b5" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_f2f0a39b-3585-4931-a798-8fdc3b8da6ae" xlink:to="loc_srt_MaximumMember_df24d459-e81f-4444-bb79-a95e57d320b5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionAxis_5b471bf4-a571-43f6-b141-fc58b8fc0a01" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:to="loc_us-gaap_RelatedPartyTransactionAxis_5b471bf4-a571-43f6-b141-fc58b8fc0a01" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionDomain_b5cd6f79-0c7d-4c43-aa92-01574bb23e75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionAxis_5b471bf4-a571-43f6-b141-fc58b8fc0a01" xlink:to="loc_us-gaap_RelatedPartyTransactionDomain_b5cd6f79-0c7d-4c43-aa92-01574bb23e75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RevenueShareAgreementMember_ab864ef4-965d-45a9-a50d-2a36d6e3aa35" xlink:href="cfms-20230331.xsd#cfms_RevenueShareAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionDomain_b5cd6f79-0c7d-4c43-aa92-01574bb23e75" xlink:to="loc_cfms_RevenueShareAgreementMember_ab864ef4-965d-45a9-a50d-2a36d6e3aa35" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_0b7b193a-f329-40c8-a5d2-1e14fbf1fbc2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyTransactionsByRelatedPartyAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:to="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_0b7b193a-f329-40c8-a5d2-1e14fbf1fbc2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RelatedPartyDomain_342c8cf2-591d-4472-9b3f-c321b6ebae65" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RelatedPartyDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyTransactionsByRelatedPartyAxis_0b7b193a-f329-40c8-a5d2-1e14fbf1fbc2" xlink:to="loc_us-gaap_RelatedPartyDomain_342c8cf2-591d-4472-9b3f-c321b6ebae65" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MembersOfScientificAdvisoryBoardMember_d888df5a-c9d5-4494-a920-336678513c6a" xlink:href="cfms-20230331.xsd#cfms_MembersOfScientificAdvisoryBoardMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RelatedPartyDomain_342c8cf2-591d-4472-9b3f-c321b6ebae65" xlink:to="loc_cfms_MembersOfScientificAdvisoryBoardMember_d888df5a-c9d5-4494-a920-336678513c6a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseAxis_f6ffcae3-23a1-4b3c-b2f6-1460a3a8c3ec" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_LitigationCaseAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:to="loc_srt_LitigationCaseAxis_f6ffcae3-23a1-4b3c-b2f6-1460a3a8c3ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_LitigationCaseTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseAxis_f6ffcae3-23a1-4b3c-b2f6-1460a3a8c3ec" xlink:to="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ConformisvMedactaMember_a1886afe-e8f3-4af8-b246-9f55687a66be" xlink:href="cfms-20230331.xsd#cfms_ConformisvMedactaMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:to="loc_cfms_ConformisvMedactaMember_a1886afe-e8f3-4af8-b246-9f55687a66be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_OsteoplasticsVConformisMember_2ab56d41-9925-40c2-ab49-7b2f3ba101e1" xlink:href="cfms-20230331.xsd#cfms_OsteoplasticsVConformisMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:to="loc_cfms_OsteoplasticsVConformisMember_2ab56d41-9925-40c2-ab49-7b2f3ba101e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ConformisVDePuyMember_397a237e-c6ec-4490-956f-ae82381cf3b4" xlink:href="cfms-20230331.xsd#cfms_ConformisVDePuyMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:to="loc_cfms_ConformisVDePuyMember_397a237e-c6ec-4490-956f-ae82381cf3b4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ConformisVExactechMember_19fc61db-93f8-4cf7-ac28-906591597893" xlink:href="cfms-20230331.xsd#cfms_ConformisVExactechMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:to="loc_cfms_ConformisVExactechMember_19fc61db-93f8-4cf7-ac28-906591597893" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ConformisVBodycadAndExactechMember_bbcafb8d-9db0-4924-a291-ebc6e58e872c" xlink:href="cfms-20230331.xsd#cfms_ConformisVBodycadAndExactechMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_LitigationCaseTypeDomain_63a752c9-20ca-49bf-94bd-cb7d203896be" xlink:to="loc_cfms_ConformisVBodycadAndExactechMember_bbcafb8d-9db0-4924-a291-ebc6e58e872c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_OtherCommitmentsLineItems"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsTable_456033c0-7d4f-4bad-b2e5-8766cf43751c" xlink:to="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RelatedPartyTransactionRequiredPaymenttoRelatedPartyfromNetRevenuesPercentage_ffb0348e-a555-4883-9cff-d400fa020d71" xlink:href="cfms-20230331.xsd#cfms_RelatedPartyTransactionRequiredPaymenttoRelatedPartyfromNetRevenuesPercentage"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_cfms_RelatedPartyTransactionRequiredPaymenttoRelatedPartyfromNetRevenuesPercentage_ffb0348e-a555-4883-9cff-d400fa020d71" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostsAndExpensesRelatedParty_1f01bd68-ace4-4e50-8046-d93a5fba1176" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostsAndExpensesRelatedParty"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_us-gaap_CostsAndExpensesRelatedParty_1f01bd68-ace4-4e50-8046-d93a5fba1176" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RelatedPartyTransactionRevenueShareExpensePercentageOnRevenue_03fb578b-edd8-4ee0-9669-1cd76c1bf973" xlink:href="cfms-20230331.xsd#cfms_RelatedPartyTransactionRevenueShareExpensePercentageOnRevenue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_cfms_RelatedPartyTransactionRevenueShareExpensePercentageOnRevenue_03fb578b-edd8-4ee0-9669-1cd76c1bf973" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyAccrualAtCarryingValue_1f24c46c-18d2-4fdc-bcf6-b9ce3e30925d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LossContingencyAccrualAtCarryingValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_us-gaap_LossContingencyAccrualAtCarryingValue_1f24c46c-18d2-4fdc-bcf6-b9ce3e30925d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber_aa735003-c23d-4364-a4d3-0ba8de80ad9c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_us-gaap_GainContingencyPatentsAllegedlyInfringedUponNumber_aa735003-c23d-4364-a4d3-0ba8de80ad9c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecurityDeposit_4d2877a5-305d-4c5c-8377-b8456868ec7c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecurityDeposit"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_us-gaap_SecurityDeposit_4d2877a5-305d-4c5c-8377-b8456868ec7c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_708b7c13-69c8-4def-893d-4362eb3aabf8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LossContingencyPatentsAllegedlyInfringedNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_OtherCommitmentsLineItems_10effac4-3c6b-4e0d-908c-aaa713cf490e" xlink:to="loc_us-gaap_LossContingencyPatentsAllegedlyInfringedNumber_708b7c13-69c8-4def-893d-4362eb3aabf8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/DebtandNotesPayableScheduleofLongTermDebtDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#DebtandNotesPayableScheduleofLongTermDebtDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/DebtandNotesPayableScheduleofLongTermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_ffc763c1-0634-47d1-9ea7-bb6eafd2c5fb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_d600fac4-a65d-4e21-b762-84679fbef8f9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_ffc763c1-0634-47d1-9ea7-bb6eafd2c5fb" xlink:to="loc_us-gaap_DebtInstrumentTable_d600fac4-a65d-4e21-b762-84679fbef8f9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_cb129010-a559-4b0c-a3e2-24b689ba58fa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_d600fac4-a65d-4e21-b762-84679fbef8f9" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_cb129010-a559-4b0c-a3e2-24b689ba58fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_ea99546c-362c-4d94-80dc-b8423bbccffc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityLenderDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_cb129010-a559-4b0c-a3e2-24b689ba58fa" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_ea99546c-362c-4d94-80dc-b8423bbccffc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MidCapFinancialServicesLLCMember_0f637a00-c48c-41bf-b1a2-f635ad6b6a72" xlink:href="cfms-20230331.xsd#cfms_MidCapFinancialServicesLLCMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_ea99546c-362c-4d94-80dc-b8423bbccffc" xlink:to="loc_cfms_MidCapFinancialServicesLLCMember_0f637a00-c48c-41bf-b1a2-f635ad6b6a72" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_4d1140e9-d570-459a-974c-d06200e43f54" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_d600fac4-a65d-4e21-b762-84679fbef8f9" xlink:to="loc_us-gaap_CreditFacilityAxis_4d1140e9-d570-459a-974c-d06200e43f54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_73fdd96b-e31f-483c-a063-e8b2c5474134" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_4d1140e9-d570-459a-974c-d06200e43f54" xlink:to="loc_us-gaap_CreditFacilityDomain_73fdd96b-e31f-483c-a063-e8b2c5474134" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_TermLoanMember_7582a014-a3b6-43a6-8082-e4c62989ec02" xlink:href="cfms-20230331.xsd#cfms_TermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_73fdd96b-e31f-483c-a063-e8b2c5474134" xlink:to="loc_cfms_TermLoanMember_7582a014-a3b6-43a6-8082-e4c62989ec02" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_7e20ed54-12e7-4d4b-911d-76c388e0106c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_d600fac4-a65d-4e21-b762-84679fbef8f9" xlink:to="loc_us-gaap_DebtInstrumentLineItems_7e20ed54-12e7-4d4b-911d-76c388e0106c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentCarryingAmount_565c6a33-e91b-4bd2-962b-be4b614aed92" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentCarryingAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7e20ed54-12e7-4d4b-911d-76c388e0106c" xlink:to="loc_us-gaap_DebtInstrumentCarryingAmount_565c6a33-e91b-4bd2-962b-be4b614aed92" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DeferredFinanceCostsNet_bdfe87fd-32e3-4c9d-91a9-813135c16342" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DeferredFinanceCostsNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7e20ed54-12e7-4d4b-911d-76c388e0106c" xlink:to="loc_us-gaap_DeferredFinanceCostsNet_bdfe87fd-32e3-4c9d-91a9-813135c16342" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LongTermDebt_cdb0fbaf-dd1c-4160-b7e0-c727ccdb4845" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LongTermDebt"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_7e20ed54-12e7-4d4b-911d-76c388e0106c" xlink:to="loc_us-gaap_LongTermDebt_cdb0fbaf-dd1c-4160-b7e0-c727ccdb4845" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/DebtandNotesPayableMaturitiesofLongTermDebtDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#DebtandNotesPayableMaturitiesofLongTermDebtDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/DebtandNotesPayableMaturitiesofLongTermDebtDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestRemainderOfFiscalYear_250b4cf2-2aae-4f9a-a01c-29887ccd6ba8" xlink:href="cfms-20230331.xsd#cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestRemainderOfFiscalYear"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:to="loc_cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestRemainderOfFiscalYear_250b4cf2-2aae-4f9a-a01c-29887ccd6ba8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LongTermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearOne_dca8d05d-b459-4c84-b3b1-f61687486479" xlink:href="cfms-20230331.xsd#cfms_LongTermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearOne"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:to="loc_cfms_LongTermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearOne_dca8d05d-b459-4c84-b3b1-f61687486479" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearTwo_b97ab573-67f2-4aa1-b9da-96329b7f2c4f" xlink:href="cfms-20230331.xsd#cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearTwo"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:to="loc_cfms_LongtermDebtMaturitiesRepaymentsOfPrincipalAndInterestInYearTwo_b97ab573-67f2-4aa1-b9da-96329b7f2c4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LongtermDebtMaturitiesRepaymentsofPrincipalAndInterestInYearThree_48401ac6-ecfd-4583-be8f-986a05e44994" xlink:href="cfms-20230331.xsd#cfms_LongtermDebtMaturitiesRepaymentsofPrincipalAndInterestInYearThree"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:to="loc_cfms_LongtermDebtMaturitiesRepaymentsofPrincipalAndInterestInYearThree_48401ac6-ecfd-4583-be8f-986a05e44994" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_LongTermDebtAndPaidInKindInterestCommitment_a00bf786-a804-4ac5-9012-ec3a076e1082" xlink:href="cfms-20230331.xsd#cfms_LongTermDebtAndPaidInKindInterestCommitment"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_364a0bc0-89af-4be0-b00b-e4b257ae88cb" xlink:to="loc_cfms_LongTermDebtAndPaidInKindInterestCommitment_a00bf786-a804-4ac5-9012-ec3a076e1082" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/totalLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/DebtandNotesPayableNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#DebtandNotesPayableNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/DebtandNotesPayableNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtDisclosureAbstract_5a07a393-0b79-4254-9c81-582c01c122b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtDisclosureAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtDisclosureAbstract_5a07a393-0b79-4254-9c81-582c01c122b7" xlink:to="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityAxis_fe7e4afe-6b5a-4562-b165-e6a0ffefa835" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_us-gaap_CreditFacilityAxis_fe7e4afe-6b5a-4562-b165-e6a0ffefa835" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CreditFacilityDomain_11566f33-d8bf-48cc-bdd9-7d3e588f2f4b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CreditFacilityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityAxis_fe7e4afe-6b5a-4562-b165-e6a0ffefa835" xlink:to="loc_us-gaap_CreditFacilityDomain_11566f33-d8bf-48cc-bdd9-7d3e588f2f4b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_TermLoanMember_9bda6e2b-c585-460e-b44b-58bd12cfd720" xlink:href="cfms-20230331.xsd#cfms_TermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_CreditFacilityDomain_11566f33-d8bf-48cc-bdd9-7d3e588f2f4b" xlink:to="loc_cfms_TermLoanMember_9bda6e2b-c585-460e-b44b-58bd12cfd720" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentAxis_46842821-b582-4e77-8b43-79d5a80e611b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_us-gaap_DebtInstrumentAxis_46842821-b582-4e77-8b43-79d5a80e611b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentNameDomain_77ac9a86-49f8-4d20-ba55-01f333e450d1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentAxis_46842821-b582-4e77-8b43-79d5a80e611b" xlink:to="loc_us-gaap_DebtInstrumentNameDomain_77ac9a86-49f8-4d20-ba55-01f333e450d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MidCapFinancialServicesLLCTermLoanMember_709cfdad-4eb3-4f68-a682-a1f6a4597a0e" xlink:href="cfms-20230331.xsd#cfms_MidCapFinancialServicesLLCTermLoanMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentNameDomain_77ac9a86-49f8-4d20-ba55-01f333e450d1" xlink:to="loc_cfms_MidCapFinancialServicesLLCTermLoanMember_709cfdad-4eb3-4f68-a682-a1f6a4597a0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityAxis_31fb3df7-f310-492c-909b-5730da95dd7e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_us-gaap_LineOfCreditFacilityAxis_31fb3df7-f310-492c-909b-5730da95dd7e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LineOfCreditFacilityLenderDomain_e2f48c36-ebc8-4cf6-b3c7-bfc4d5ec47b0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LineOfCreditFacilityLenderDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityAxis_31fb3df7-f310-492c-909b-5730da95dd7e" xlink:to="loc_us-gaap_LineOfCreditFacilityLenderDomain_e2f48c36-ebc8-4cf6-b3c7-bfc4d5ec47b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MidCapFinancialServicesLLCMember_fbf821b9-263d-402f-8d2d-3ec7ecdee5d1" xlink:href="cfms-20230331.xsd#cfms_MidCapFinancialServicesLLCMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_LineOfCreditFacilityLenderDomain_e2f48c36-ebc8-4cf6-b3c7-bfc4d5ec47b0" xlink:to="loc_cfms_MidCapFinancialServicesLLCMember_fbf821b9-263d-402f-8d2d-3ec7ecdee5d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateAxis_5c0d7665-360a-4cb2-b638-aff672c0e715" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableRateAxis"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_us-gaap_VariableRateAxis_5c0d7665-360a-4cb2-b638-aff672c0e715" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_VariableRateDomain_754b4245-3dcd-44c6-bc2e-f5c09ffca77f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_VariableRateDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateAxis_5c0d7665-360a-4cb2-b638-aff672c0e715" xlink:to="loc_us-gaap_VariableRateDomain_754b4245-3dcd-44c6-bc2e-f5c09ffca77f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_57b7eed8-c308-48a8-8234-b0ac744571bb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_LondonInterbankOfferedRateLIBORMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_754b4245-3dcd-44c6-bc2e-f5c09ffca77f" xlink:to="loc_us-gaap_LondonInterbankOfferedRateLIBORMember_57b7eed8-c308-48a8-8234-b0ac744571bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SecuredOvernightFinancingRateSofrOvernightIndexSwapRateMember_accb9ea8-6fef-4746-bfa5-d851f1645687" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SecuredOvernightFinancingRateSofrOvernightIndexSwapRateMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_VariableRateDomain_754b4245-3dcd-44c6-bc2e-f5c09ffca77f" xlink:to="loc_us-gaap_SecuredOvernightFinancingRateSofrOvernightIndexSwapRateMember_accb9ea8-6fef-4746-bfa5-d851f1645687" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_50588f11-f34b-4e08-a54b-04ddfbaadf81" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_srt_RangeAxis_50588f11-f34b-4e08-a54b-04ddfbaadf81" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_f8932fcc-3d59-4dbf-9660-ae6594dab547" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_50588f11-f34b-4e08-a54b-04ddfbaadf81" xlink:to="loc_srt_RangeMember_f8932fcc-3d59-4dbf-9660-ae6594dab547" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_eb96af0b-fc3f-4fbd-a0ff-f95cde103f93" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_f8932fcc-3d59-4dbf-9660-ae6594dab547" xlink:to="loc_srt_MinimumMember_eb96af0b-fc3f-4fbd-a0ff-f95cde103f93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentLineItems"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentTable_c1ddf4b7-f744-4d5c-bae7-418c5d504f10" xlink:to="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentTerm_246b8bc5-2fe0-40f2-ae5f-4be74966f632" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentTerm"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_us-gaap_DebtInstrumentTerm_246b8bc5-2fe0-40f2-ae5f-4be74966f632" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentFaceAmount_cf47598e-9b35-47bf-8f9c-22caa4c1c3ea" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentFaceAmount"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_us-gaap_DebtInstrumentFaceAmount_cf47598e-9b35-47bf-8f9c-22caa4c1c3ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_373cb9da-c437-46eb-9486-c06a4fa4ac04" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentBasisSpreadOnVariableRate1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_us-gaap_DebtInstrumentBasisSpreadOnVariableRate1_373cb9da-c437-46eb-9486-c06a4fa4ac04" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_DebtInstrumentVariableRate_1e19d7ff-7b7f-463b-aeaf-cc4f80d61914" xlink:href="cfms-20230331.xsd#cfms_DebtInstrumentVariableRate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_cfms_DebtInstrumentVariableRate_1e19d7ff-7b7f-463b-aeaf-cc4f80d61914" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_DebtInstrumentOriginationFeeDueAtClosing_8a4c89a3-b474-4b34-8634-927c9d31feab" xlink:href="cfms-20230331.xsd#cfms_DebtInstrumentOriginationFeeDueAtClosing"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_cfms_DebtInstrumentOriginationFeeDueAtClosing_8a4c89a3-b474-4b34-8634-927c9d31feab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_DebtInstrumentFinalPaymentFee_bab27c53-e1c3-4c1b-a87b-c97a1ce1092a" xlink:href="cfms-20230331.xsd#cfms_DebtInstrumentFinalPaymentFee"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_cfms_DebtInstrumentFinalPaymentFee_bab27c53-e1c3-4c1b-a87b-c97a1ce1092a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_DebtInstrumentConvertibleLiquidationPreferenceValue_c1d9ec36-8996-4626-a67d-b6a8b3398704" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_DebtInstrumentConvertibleLiquidationPreferenceValue"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_us-gaap_DebtInstrumentConvertibleLiquidationPreferenceValue_c1d9ec36-8996-4626-a67d-b6a8b3398704" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f4df14be-14e1-4179-a09c-59438c131b38" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GainsLossesOnExtinguishmentOfDebt"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_DebtInstrumentLineItems_99bdfeb2-b7b3-4f38-b75b-715b7554715f" xlink:to="loc_us-gaap_GainsLossesOnExtinguishmentOfDebt_f4df14be-14e1-4179-a09c-59438c131b38" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityCommonStockDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityCommonStockDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityCommonStockDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_af93dbf9-ceb2-449a-98b1-d56c7157ccf2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_CumulativeCommonStockDividendsDeclared_5d661d5c-d51c-4a5c-85c7-94b9eb790d91" xlink:href="cfms-20230331.xsd#cfms_CumulativeCommonStockDividendsDeclared"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_af93dbf9-ceb2-449a-98b1-d56c7157ccf2" xlink:to="loc_cfms_CumulativeCommonStockDividendsDeclared_5d661d5c-d51c-4a5c-85c7-94b9eb790d91" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_db8d56ab-c945-43c0-9704-9f5c133ba584" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_af93dbf9-ceb2-449a-98b1-d56c7157ccf2" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_db8d56ab-c945-43c0-9704-9f5c133ba584" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityReverseStockSplitDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityReverseStockSplitDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityReverseStockSplitDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_2b8e882a-b67c-4df1-afb5-69c158d11dbc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_2b8e882a-b67c-4df1-afb5-69c158d11dbc" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeAxis_234d8755-a5a9-4719-96cf-b674d10f4f22" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:to="loc_srt_RangeAxis_234d8755-a5a9-4719-96cf-b674d10f4f22" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_RangeMember_3254d1e1-3d3d-4b1f-838f-4cee63414286" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_RangeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeAxis_234d8755-a5a9-4719-96cf-b674d10f4f22" xlink:to="loc_srt_RangeMember_3254d1e1-3d3d-4b1f-838f-4cee63414286" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MinimumMember_aa944c5b-90d3-4f6f-a319-ac90100485bc" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MinimumMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_3254d1e1-3d3d-4b1f-838f-4cee63414286" xlink:to="loc_srt_MinimumMember_aa944c5b-90d3-4f6f-a319-ac90100485bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_MaximumMember_731c8d30-9a42-4c96-b7fe-b3584177c5a5" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_MaximumMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_RangeMember_3254d1e1-3d3d-4b1f-838f-4cee63414286" xlink:to="loc_srt_MaximumMember_731c8d30-9a42-4c96-b7fe-b3584177c5a5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_FixedRatioAxis_5d44b86e-e651-4d22-9b0f-4913c6ba4f14" xlink:href="cfms-20230331.xsd#cfms_FixedRatioAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:to="loc_cfms_FixedRatioAxis_5d44b86e-e651-4d22-9b0f-4913c6ba4f14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_FixedRatioDomain_3ed62a6c-36ee-4e07-8bd0-038f2d617a2c" xlink:href="cfms-20230331.xsd#cfms_FixedRatioDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_FixedRatioAxis_5d44b86e-e651-4d22-9b0f-4913c6ba4f14" xlink:to="loc_cfms_FixedRatioDomain_3ed62a6c-36ee-4e07-8bd0-038f2d617a2c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_FixedRatioOneMember_cf8012b1-7660-47aa-93b0-929f8294dcee" xlink:href="cfms-20230331.xsd#cfms_FixedRatioOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_FixedRatioDomain_3ed62a6c-36ee-4e07-8bd0-038f2d617a2c" xlink:to="loc_cfms_FixedRatioOneMember_cf8012b1-7660-47aa-93b0-929f8294dcee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_FixedRatioTwoMember_33a81c04-18d0-4bfa-ba74-a9bcc544408c" xlink:href="cfms-20230331.xsd#cfms_FixedRatioTwoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_FixedRatioDomain_3ed62a6c-36ee-4e07-8bd0-038f2d617a2c" xlink:to="loc_cfms_FixedRatioTwoMember_33a81c04-18d0-4bfa-ba74-a9bcc544408c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_FixedRatioThreeMember_37ab1fe0-213b-4c6e-86b1-bde36b52781b" xlink:href="cfms-20230331.xsd#cfms_FixedRatioThreeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_FixedRatioDomain_3ed62a6c-36ee-4e07-8bd0-038f2d617a2c" xlink:to="loc_cfms_FixedRatioThreeMember_37ab1fe0-213b-4c6e-86b1-bde36b52781b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ApprovedRatioAxis_3724a679-5946-4b8b-bb92-e834914f400a" xlink:href="cfms-20230331.xsd#cfms_ApprovedRatioAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:to="loc_cfms_ApprovedRatioAxis_3724a679-5946-4b8b-bb92-e834914f400a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ApprovedRatioDomain_26a1f7f1-c7c1-495e-b302-2237e838b703" xlink:href="cfms-20230331.xsd#cfms_ApprovedRatioDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ApprovedRatioAxis_3724a679-5946-4b8b-bb92-e834914f400a" xlink:to="loc_cfms_ApprovedRatioDomain_26a1f7f1-c7c1-495e-b302-2237e838b703" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ApprovedRatioOneMember_cb0270a7-4668-4a7d-880d-86048e282d51" xlink:href="cfms-20230331.xsd#cfms_ApprovedRatioOneMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ApprovedRatioDomain_26a1f7f1-c7c1-495e-b302-2237e838b703" xlink:to="loc_cfms_ApprovedRatioOneMember_cb0270a7-4668-4a7d-880d-86048e282d51" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ApprovedRatioTwoMember_7833bf8b-9df7-4a37-a704-87e40615a178" xlink:href="cfms-20230331.xsd#cfms_ApprovedRatioTwoMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ApprovedRatioDomain_26a1f7f1-c7c1-495e-b302-2237e838b703" xlink:to="loc_cfms_ApprovedRatioTwoMember_7833bf8b-9df7-4a37-a704-87e40615a178" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ApprovedRatioThreeMember_53d62ddb-6218-457e-acec-091835ee4b59" xlink:href="cfms-20230331.xsd#cfms_ApprovedRatioThreeMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_ApprovedRatioDomain_26a1f7f1-c7c1-495e-b302-2237e838b703" xlink:to="loc_cfms_ApprovedRatioThreeMember_53d62ddb-6218-457e-acec-091835ee4b59" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_ccb6e08a-0223-4735-b947-0de908af3b80" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_7057b627-9f5c-4d35-80b6-b8f53a5c516e" xlink:to="loc_us-gaap_ClassOfStockLineItems_ccb6e08a-0223-4735-b947-0de908af3b80" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_2d8f667e-2d41-4a0d-a76e-93d6a3078543" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_ccb6e08a-0223-4735-b947-0de908af3b80" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_2d8f667e-2d41-4a0d-a76e-93d6a3078543" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockSharesAuthorized_76cf822d-c2fc-4815-8f4b-61f6938467c3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockSharesAuthorized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_ccb6e08a-0223-4735-b947-0de908af3b80" xlink:to="loc_us-gaap_CommonStockSharesAuthorized_76cf822d-c2fc-4815-8f4b-61f6938467c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockParOrStatedValuePerShare_ea3eb34c-cc5f-4975-baec-b34387958377" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockParOrStatedValuePerShare"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_ccb6e08a-0223-4735-b947-0de908af3b80" xlink:to="loc_us-gaap_CommonStockParOrStatedValuePerShare_ea3eb34c-cc5f-4975-baec-b34387958377" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityPreferredStockDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityPreferredStockDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityPreferredStockDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_121f20b1-40b4-4f54-ac51-171a87721c59" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesAuthorized_0595dc86-d7c8-4cdb-9ac9-6622db1e4e9b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesAuthorized"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_121f20b1-40b4-4f54-ac51-171a87721c59" xlink:to="loc_us-gaap_PreferredStockSharesAuthorized_0595dc86-d7c8-4cdb-9ac9-6622db1e4e9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockParOrStatedValuePerShare_fee100ce-9f7b-46d3-bd4b-f6851a634679" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockParOrStatedValuePerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_121f20b1-40b4-4f54-ac51-171a87721c59" xlink:to="loc_us-gaap_PreferredStockParOrStatedValuePerShare_fee100ce-9f7b-46d3-bd4b-f6851a634679" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesIssued_f0e8a4ac-2854-40ff-9ba3-cd75131c6837" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesIssued"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_121f20b1-40b4-4f54-ac51-171a87721c59" xlink:to="loc_us-gaap_PreferredStockSharesIssued_f0e8a4ac-2854-40ff-9ba3-cd75131c6837" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PreferredStockSharesOutstanding_06352b7c-c6c8-413d-8938-288fb6cc6e5d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PreferredStockSharesOutstanding"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_121f20b1-40b4-4f54-ac51-171a87721c59" xlink:to="loc_us-gaap_PreferredStockSharesOutstanding_06352b7c-c6c8-413d-8938-288fb6cc6e5d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityDemandRegistrationRightsDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityDemandRegistrationRightsDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityDemandRegistrationRightsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_acc20d22-72d9-4c1c-b1de-f0d7dae1ac3a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfStockByClassTable_59a7ea90-2159-4c1d-b876-46bb62dec4b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfStockByClassTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_acc20d22-72d9-4c1c-b1de-f0d7dae1ac3a" xlink:to="loc_us-gaap_ScheduleOfStockByClassTable_59a7ea90-2159-4c1d-b876-46bb62dec4b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RegistrationPaymentArrangementByArrangementAxis_e542f3b2-50f8-46c7-a84f-06cfcb23fcbb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RegistrationPaymentArrangementByArrangementAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_59a7ea90-2159-4c1d-b876-46bb62dec4b7" xlink:to="loc_us-gaap_RegistrationPaymentArrangementByArrangementAxis_e542f3b2-50f8-46c7-a84f-06cfcb23fcbb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RegistrationPaymentArrangementArrangementDomain_0d4b90ac-e67a-4506-bcb0-ff48238712ef" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RegistrationPaymentArrangementArrangementDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RegistrationPaymentArrangementByArrangementAxis_e542f3b2-50f8-46c7-a84f-06cfcb23fcbb" xlink:to="loc_us-gaap_RegistrationPaymentArrangementArrangementDomain_0d4b90ac-e67a-4506-bcb0-ff48238712ef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_A2019RightsAgreementMember_bdb8c075-7c7f-4971-9421-faf26f6f6f18" xlink:href="cfms-20230331.xsd#cfms_A2019RightsAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RegistrationPaymentArrangementArrangementDomain_0d4b90ac-e67a-4506-bcb0-ff48238712ef" xlink:to="loc_cfms_A2019RightsAgreementMember_bdb8c075-7c7f-4971-9421-faf26f6f6f18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfStockLineItems_ce5a0862-50d1-4000-9eac-072431d137bb" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfStockLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfStockByClassTable_59a7ea90-2159-4c1d-b876-46bb62dec4b7" xlink:to="loc_us-gaap_ClassOfStockLineItems_ce5a0862-50d1-4000-9eac-072431d137bb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_DemandRegistrationRightsAbstract_f45b6092-1c6a-496f-b0b8-78affe9610a7" xlink:href="cfms-20230331.xsd#cfms_DemandRegistrationRightsAbstract"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfStockLineItems_ce5a0862-50d1-4000-9eac-072431d137bb" xlink:to="loc_cfms_DemandRegistrationRightsAbstract_f45b6092-1c6a-496f-b0b8-78affe9610a7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MaximumDaysToRegisterForResaleSharesHeldByInvestors_5a12f042-80a1-4ed4-83e6-4c646f939b6c" xlink:href="cfms-20230331.xsd#cfms_MaximumDaysToRegisterForResaleSharesHeldByInvestors"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_DemandRegistrationRightsAbstract_f45b6092-1c6a-496f-b0b8-78affe9610a7" xlink:to="loc_cfms_MaximumDaysToRegisterForResaleSharesHeldByInvestors_5a12f042-80a1-4ed4-83e6-4c646f939b6c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityAttheMarketProgramDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityAttheMarketProgramDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityAttheMarketProgramDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_0fb7eb8f-af84-4bc5-b49b-012dc7699402" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d3d995c1-5477-4daf-9fee-0b7c9aca982a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_0fb7eb8f-af84-4bc5-b49b-012dc7699402" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d3d995c1-5477-4daf-9fee-0b7c9aca982a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_15af7bdf-4fe4-49a4-8c12-b71bf56249e1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d3d995c1-5477-4daf-9fee-0b7c9aca982a" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_15af7bdf-4fe4-49a4-8c12-b71bf56249e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_25795c96-0a6b-4fd1-943a-df8d00587788" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_15af7bdf-4fe4-49a4-8c12-b71bf56249e1" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_25795c96-0a6b-4fd1-943a-df8d00587788" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_CowenSalesAgreementMember_67977ee4-cc05-4035-b7e7-dc696872504c" xlink:href="cfms-20230331.xsd#cfms_CowenSalesAgreementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_25795c96-0a6b-4fd1-943a-df8d00587788" xlink:to="loc_cfms_CowenSalesAgreementMember_67977ee4-cc05-4035-b7e7-dc696872504c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_6e274df8-e91d-4d69-841b-fd20c80a1135" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_d3d995c1-5477-4daf-9fee-0b7c9aca982a" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_6e274df8-e91d-4d69-841b-fd20c80a1135" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_SaleofStockEquityIssuableAmount_e0aec5bb-5458-49da-a25d-17401da09d5e" xlink:href="cfms-20230331.xsd#cfms_SaleofStockEquityIssuableAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_6e274df8-e91d-4d69-841b-fd20c80a1135" xlink:to="loc_cfms_SaleofStockEquityIssuableAmount_e0aec5bb-5458-49da-a25d-17401da09d5e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_SaleOfStockBrokerCommissionsPercent_41f7e01c-7cf2-45f6-a8b3-ca4f9c2fda9e" xlink:href="cfms-20230331.xsd#cfms_SaleOfStockBrokerCommissionsPercent"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_6e274df8-e91d-4d69-841b-fd20c80a1135" xlink:to="loc_cfms_SaleOfStockBrokerCommissionsPercent_41f7e01c-7cf2-45f6-a8b3-ca4f9c2fda9e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquity2021CommonStockOfferingDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquity2021CommonStockOfferingDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquity2021CommonStockOfferingDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_ef2a1eaf-1c30-4a27-be2a-fe50cc567af0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_39bcaa9d-cc94-48d4-b6ae-dce24b5cb7d6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_ef2a1eaf-1c30-4a27-be2a-fe50cc567af0" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_39bcaa9d-cc94-48d4-b6ae-dce24b5cb7d6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_b5983cc3-751b-4014-a639-8cd9233ac66f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_39bcaa9d-cc94-48d4-b6ae-dce24b5cb7d6" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_b5983cc3-751b-4014-a639-8cd9233ac66f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_030d8ea3-702a-4e37-af1a-0d394cecacf3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_b5983cc3-751b-4014-a639-8cd9233ac66f" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_030d8ea3-702a-4e37-af1a-0d394cecacf3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ShelfRegistrationStatementMember_7801dfb6-e91f-4a45-b563-55d4e30a1eb7" xlink:href="cfms-20230331.xsd#cfms_ShelfRegistrationStatementMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_030d8ea3-702a-4e37-af1a-0d394cecacf3" xlink:to="loc_cfms_ShelfRegistrationStatementMember_7801dfb6-e91f-4a45-b563-55d4e30a1eb7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_39bcaa9d-cc94-48d4-b6ae-dce24b5cb7d6" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_82d6a5b8-3da1-400d-8e12-d43ad919250f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_82d6a5b8-3da1-400d-8e12-d43ad919250f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_1eca1799-ad5c-4294-9cf2-07458cb71e83" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_1eca1799-ad5c-4294-9cf2-07458cb71e83" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_eb71f6c9-e086-446e-ab79-c208c8c33b40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_eb71f6c9-e086-446e-ab79-c208c8c33b40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_a8f47605-1f0a-4bf1-9e12-11a040c26712" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_8fbdd313-e3f5-4675-983d-aa0a1a313ec5" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_a8f47605-1f0a-4bf1-9e12-11a040c26712" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityRegisteredDirectOfferingDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityRegisteredDirectOfferingDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityRegisteredDirectOfferingDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_96992608-6341-438a-9d56-ff765f3ddb75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_4343cf91-7c8e-490d-82e7-ecc8b45b741a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_96992608-6341-438a-9d56-ff765f3ddb75" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_4343cf91-7c8e-490d-82e7-ecc8b45b741a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_1cbe6f90-84d5-4942-a827-a44fb481699d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_4343cf91-7c8e-490d-82e7-ecc8b45b741a" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_1cbe6f90-84d5-4942-a827-a44fb481699d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_249a4624-d7f9-46e5-a14e-a91579be46ea" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_1cbe6f90-84d5-4942-a827-a44fb481699d" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_249a4624-d7f9-46e5-a14e-a91579be46ea" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RegisteredDirectOfferingMember_34fb0080-06b0-4d3f-a61c-127c57f2493c" xlink:href="cfms-20230331.xsd#cfms_RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_249a4624-d7f9-46e5-a14e-a91579be46ea" xlink:to="loc_cfms_RegisteredDirectOfferingMember_34fb0080-06b0-4d3f-a61c-127c57f2493c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_22cd51e9-36df-44de-8511-bc819bf19053" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_4343cf91-7c8e-490d-82e7-ecc8b45b741a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_22cd51e9-36df-44de-8511-bc819bf19053" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_2297e15c-5514-4fc6-b287-8c34ccf4cffc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_22cd51e9-36df-44de-8511-bc819bf19053" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_2297e15c-5514-4fc6-b287-8c34ccf4cffc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_PreFundedWarrantsMember_22481ab9-54d9-49ae-a0d6-a1faba24ff69" xlink:href="cfms-20230331.xsd#cfms_PreFundedWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_2297e15c-5514-4fc6-b287-8c34ccf4cffc" xlink:to="loc_cfms_PreFundedWarrantsMember_22481ab9-54d9-49ae-a0d6-a1faba24ff69" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_WarrantsForPurchaseOfCommonStockMember_4ca5adfa-cd72-4776-929b-f82d5d194b78" xlink:href="cfms-20230331.xsd#cfms_WarrantsForPurchaseOfCommonStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_2297e15c-5514-4fc6-b287-8c34ccf4cffc" xlink:to="loc_cfms_WarrantsForPurchaseOfCommonStockMember_4ca5adfa-cd72-4776-929b-f82d5d194b78" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_4343cf91-7c8e-490d-82e7-ecc8b45b741a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_a02bc4a6-5a53-43f3-bb89-e852237b6ac1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_a02bc4a6-5a53-43f3-bb89-e852237b6ac1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_dede99e6-ab48-4e47-b6fa-7d416b0248e7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_dede99e6-ab48-4e47-b6fa-7d416b0248e7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_SaleofStockConsiderationReceivedonTransactionGross_24ddaac1-3902-48e3-a0dc-4c4443ae44d4" xlink:href="cfms-20230331.xsd#cfms_SaleofStockConsiderationReceivedonTransactionGross"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_cfms_SaleofStockConsiderationReceivedonTransactionGross_24ddaac1-3902-48e3-a0dc-4c4443ae44d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_NumberOfCommonStockSharesAndWarrantsPerUnit_6c0c5bcf-8e03-4ea5-a885-0308ddf9207f" xlink:href="cfms-20230331.xsd#cfms_NumberOfCommonStockSharesAndWarrantsPerUnit"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_cfms_NumberOfCommonStockSharesAndWarrantsPerUnit_6c0c5bcf-8e03-4ea5-a885-0308ddf9207f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockPricePerShare_dcfc33e1-e7d7-4ebd-8e23-5e5da16fb55b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockPricePerShare"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_us-gaap_SaleOfStockPricePerShare_dcfc33e1-e7d7-4ebd-8e23-5e5da16fb55b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_9fe39ca0-3fb3-45cd-a19c-304ad1f771a0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_9fe39ca0-3fb3-45cd-a19c-304ad1f771a0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassOfWarrantOrRightExpirationPeriod_debae7e4-9400-408d-94c6-f178e67fabf7" xlink:href="cfms-20230331.xsd#cfms_ClassOfWarrantOrRightExpirationPeriod"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_cfms_ClassOfWarrantOrRightExpirationPeriod_debae7e4-9400-408d-94c6-f178e67fabf7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassOfWarrantOrRightMaximumPercentageOfCommonStockOwnedAfterExercise_af537e24-fe24-4563-a9d9-78bebb7422be" xlink:href="cfms-20230331.xsd#cfms_ClassOfWarrantOrRightMaximumPercentageOfCommonStockOwnedAfterExercise"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_cfms_ClassOfWarrantOrRightMaximumPercentageOfCommonStockOwnedAfterExercise_af537e24-fe24-4563-a9d9-78bebb7422be" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_8f527822-015d-4646-90b2-854eb4425d75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockConsiderationReceivedOnTransaction"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_94c14b0b-6d66-4d7e-bcce-0d7a80c0525a" xlink:to="loc_us-gaap_SaleOfStockConsiderationReceivedOnTransaction_8f527822-015d-4646-90b2-854eb4425d75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityWarrantsDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_4b23cdbf-7fb4-40bb-84b3-dd86117d4415" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_4b23cdbf-7fb4-40bb-84b3-dd86117d4415" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SubsidiarySaleOfStockAxis_b12e2aaa-e13a-48c1-82d8-e5e5b82c435a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SubsidiarySaleOfStockAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:to="loc_us-gaap_SubsidiarySaleOfStockAxis_b12e2aaa-e13a-48c1-82d8-e5e5b82c435a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNameOfTransactionDomain_73ebb979-12e7-45ea-9586-bf4d630acc14" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNameOfTransactionDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SubsidiarySaleOfStockAxis_b12e2aaa-e13a-48c1-82d8-e5e5b82c435a" xlink:to="loc_us-gaap_SaleOfStockNameOfTransactionDomain_73ebb979-12e7-45ea-9586-bf4d630acc14" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_RegisteredDirectOfferingMember_7b8d1fd5-a47b-4e96-8f26-faecf1d9835e" xlink:href="cfms-20230331.xsd#cfms_RegisteredDirectOfferingMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SaleOfStockNameOfTransactionDomain_73ebb979-12e7-45ea-9586-bf4d630acc14" xlink:to="loc_cfms_RegisteredDirectOfferingMember_7b8d1fd5-a47b-4e96-8f26-faecf1d9835e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeAxis_e2c788a6-e089-4e2e-b2b9-790e3482c8ee" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:to="loc_us-gaap_MeasurementInputTypeAxis_e2c788a6-e089-4e2e-b2b9-790e3482c8ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputTypeDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeAxis_e2c788a6-e089-4e2e-b2b9-790e3482c8ee" xlink:to="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExpectedTermMember_9d00ffbb-02ad-48e7-9dd8-28d767b318ec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputExpectedTermMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_us-gaap_MeasurementInputExpectedTermMember_9d00ffbb-02ad-48e7-9dd8-28d767b318ec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_f1c3f6ac-0004-4529-b520-2e8ed29abbd4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputRiskFreeInterestRateMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_us-gaap_MeasurementInputRiskFreeInterestRateMember_f1c3f6ac-0004-4529-b520-2e8ed29abbd4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_MeasurementInputDividendYieldMember_8e99b521-5b7c-4eeb-a0a0-9f8f76a2221e" xlink:href="cfms-20230331.xsd#cfms_MeasurementInputDividendYieldMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_cfms_MeasurementInputDividendYieldMember_8e99b521-5b7c-4eeb-a0a0-9f8f76a2221e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputPriceVolatilityMember_c0df14e0-e936-454d-bcb1-d40055aba844" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputPriceVolatilityMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_us-gaap_MeasurementInputPriceVolatilityMember_c0df14e0-e936-454d-bcb1-d40055aba844" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputExercisePriceMember_03b81583-c733-43be-8d2e-7e89feffded5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputExercisePriceMember"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_us-gaap_MeasurementInputExercisePriceMember_03b81583-c733-43be-8d2e-7e89feffded5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_MeasurementInputSharePriceMember_00b4f97e-34e9-4fd5-a694-29069deee8dc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_MeasurementInputSharePriceMember"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_MeasurementInputTypeDomain_641a91b0-a051-413c-9c64-9606d92a9ea5" xlink:to="loc_us-gaap_MeasurementInputSharePriceMember_00b4f97e-34e9-4fd5-a694-29069deee8dc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_0d215351-2bb2-4c78-8ec8-3782e4865526" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_0d215351-2bb2-4c78-8ec8-3782e4865526" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_a499de18-c75e-4a89-8ae8-9c4214fb7173" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_0d215351-2bb2-4c78-8ec8-3782e4865526" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_a499de18-c75e-4a89-8ae8-9c4214fb7173" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_PreFundedWarrantsMember_68cb7080-1a37-4d87-9cec-33ae704db87b" xlink:href="cfms-20230331.xsd#cfms_PreFundedWarrantsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_a499de18-c75e-4a89-8ae8-9c4214fb7173" xlink:to="loc_cfms_PreFundedWarrantsMember_68cb7080-1a37-4d87-9cec-33ae704db87b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_WarrantsForPurchaseOfCommonStockMember_ef294d0b-2bf3-4b5e-a515-31c6bfd063f1" xlink:href="cfms-20230331.xsd#cfms_WarrantsForPurchaseOfCommonStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_a499de18-c75e-4a89-8ae8-9c4214fb7173" xlink:to="loc_cfms_WarrantsForPurchaseOfCommonStockMember_ef294d0b-2bf3-4b5e-a515-31c6bfd063f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_cc2138b9-1955-44be-a13d-12787f47f39d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_d8a26742-985e-402b-9e24-fb84d2391b75" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_SaleOfStockNumberOfSharesIssuedInTransaction_d8a26742-985e-402b-9e24-fb84d2391b75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_7ad5febb-0025-4f1b-8ed6-2348bddf0686" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_7ad5febb-0025-4f1b-8ed6-2348bddf0686" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_a63d4273-157c-4bd9-a56d-440f7d0156e2" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_a63d4273-157c-4bd9-a56d-440f7d0156e2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_0caa74d1-1913-4d46-b575-d60d574ccfa1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_0caa74d1-1913-4d46-b575-d60d574ccfa1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_fd1d717c-3945-40a9-a6ef-cc9ca464f81a" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_fd1d717c-3945-40a9-a6ef-cc9ca464f81a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingTerm_32f1a889-2fc0-4021-8e1e-2c8347b24b29" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WarrantsAndRightsOutstandingTerm"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingTerm_32f1a889-2fc0-4021-8e1e-2c8347b24b29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstanding_42a0406a-5637-461d-8f51-f50de137d066" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WarrantsAndRightsOutstanding"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstanding_42a0406a-5637-461d-8f51-f50de137d066" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_WarrantsandRightsOutstandingMeasurementInputTerm_d4789bfc-b7bc-4a10-85cb-c71a398c1de0" xlink:href="cfms-20230331.xsd#cfms_WarrantsandRightsOutstandingMeasurementInputTerm"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_cfms_WarrantsandRightsOutstandingMeasurementInputTerm_d4789bfc-b7bc-4a10-85cb-c71a398c1de0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_609fe4ff-f293-47c4-b93b-dfe0a6b46e31" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_WarrantsAndRightsOutstandingMeasurementInput"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_WarrantsAndRightsOutstandingMeasurementInput_609fe4ff-f293-47c4-b93b-dfe0a6b46e31" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_d95c8e3a-27d4-4fac-98d7-4a75cb3ee075" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_496dadd3-e28d-4056-b8e3-83dfcaec048d" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_d95c8e3a-27d4-4fac-98d7-4a75cb3ee075" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityWarrantsandCommonStockWarrantsDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityWarrantsandCommonStockWarrantsDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityWarrantsandCommonStockWarrantsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_b0e9860a-b827-4b5a-a077-c5f08d0d0421" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightTable_fb576900-9280-46e5-b04d-43fba2ebabec" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_b0e9860a-b827-4b5a-a077-c5f08d0d0421" xlink:to="loc_us-gaap_ClassOfWarrantOrRightTable_fb576900-9280-46e5-b04d-43fba2ebabec" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightAxis_d6d0f407-d024-442a-be6b-1ada01d1f5c6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_fb576900-9280-46e5-b04d-43fba2ebabec" xlink:to="loc_us-gaap_ClassOfWarrantOrRightAxis_d6d0f407-d024-442a-be6b-1ada01d1f5c6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightDomain_e6b024eb-d433-4d5b-a4d7-f8b72bc644d2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightAxis_d6d0f407-d024-442a-be6b-1ada01d1f5c6" xlink:to="loc_us-gaap_ClassOfWarrantOrRightDomain_e6b024eb-d433-4d5b-a4d7-f8b72bc644d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_WarrantsForPurchaseOfCommonStockMember_892856ae-8a55-48d7-b68d-483e192d510a" xlink:href="cfms-20230331.xsd#cfms_WarrantsForPurchaseOfCommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightDomain_e6b024eb-d433-4d5b-a4d7-f8b72bc644d2" xlink:to="loc_cfms_WarrantsForPurchaseOfCommonStockMember_892856ae-8a55-48d7-b68d-483e192d510a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightTable_fb576900-9280-46e5-b04d-43fba2ebabec" xlink:to="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:href="cfms-20230331.xsd#cfms_StockWarrantsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_8237c62c-ded2-4a3f-ba9d-5e72d6b3deef" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_8237c62c-ded2-4a3f-ba9d-5e72d6b3deef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_624831e4-b11e-43da-8a9a-da0cbfe47e29" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:to="loc_cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_624831e4-b11e-43da-8a9a-da0cbfe47e29" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_2cd54d98-9c9c-49d5-9fc7-f222e04dbb99" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:to="loc_cfms_ClassofWarrantorRightNumberofSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_2cd54d98-9c9c-49d5-9fc7-f222e04dbb99" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsCancelledOrExpiredDuringPeriod_84bcc1a4-73fc-4e18-b823-715f603c26c1" xlink:href="cfms-20230331.xsd#cfms_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsCancelledOrExpiredDuringPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:to="loc_cfms_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRightsCancelledOrExpiredDuringPeriod_84bcc1a4-73fc-4e18-b823-715f603c26c1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_a27bc3fb-490c-4031-8bc8-ac627a038e4f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingRollForward_2ea9981e-42ad-41a4-a31f-a1825a8f2bc8" xlink:to="loc_us-gaap_ClassOfWarrantOrRightNumberOfSecuritiesCalledByWarrantsOrRights_a27bc3fb-490c-4031-8bc8-ac627a038e4f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:href="cfms-20230331.xsd#cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_afbe5db5-c7b7-44eb-8496-8bcbff646000" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_afbe5db5-c7b7-44eb-8496-8bcbff646000" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsGrantedDuringPeriod_68757ce2-8c85-4bd6-a66d-1fe158528587" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsGrantedDuringPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:to="loc_cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsGrantedDuringPeriod_68757ce2-8c85-4bd6-a66d-1fe158528587" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsExercisedDuringPeriod_35ebed7b-a7ef-4e85-b8aa-0c170f8dbb40" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsExercisedDuringPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:to="loc_cfms_ClassofWarrantorRightExercisePriceofWarrantsorRightsExercisedDuringPeriod_35ebed7b-a7ef-4e85-b8aa-0c170f8dbb40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsCancelledOrExpiredDuringPeriod_cb74fd40-fb2f-43ea-9070-e93af79ef112" xlink:href="cfms-20230331.xsd#cfms_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsCancelledOrExpiredDuringPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:to="loc_cfms_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRightsCancelledOrExpiredDuringPeriod_cb74fd40-fb2f-43ea-9070-e93af79ef112" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_bba4482e-e0fa-4b61-bc66-f4e4d9f87329" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsOutstandingWeightedAverageExercisePriceRollForward_a1cb7b3e-5227-4e9e-87ce-7454ee61c3e1" xlink:to="loc_us-gaap_ClassOfWarrantOrRightExercisePriceOfWarrantsOrRights1_bba4482e-e0fa-4b61-bc66-f4e4d9f87329" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_StockWarrantsWeightedAverageRemainingContractualLifeRollForward_35d7e4c2-5d3a-42ec-af02-2cc455ec0619" xlink:href="cfms-20230331.xsd#cfms_StockWarrantsWeightedAverageRemainingContractualLifeRollForward"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_cfms_StockWarrantsWeightedAverageRemainingContractualLifeRollForward_35d7e4c2-5d3a-42ec-af02-2cc455ec0619" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassOfWarrantOrRightWeightedAverageRemainingContractualLife_429716b8-1d24-40bd-88ca-e5f3f570e303" xlink:href="cfms-20230331.xsd#cfms_ClassOfWarrantOrRightWeightedAverageRemainingContractualLife"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAverageRemainingContractualLifeRollForward_35d7e4c2-5d3a-42ec-af02-2cc455ec0619" xlink:to="loc_cfms_ClassOfWarrantOrRightWeightedAverageRemainingContractualLife_429716b8-1d24-40bd-88ca-e5f3f570e303" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:href="cfms-20230331.xsd#cfms_StockWarrantsNumberofWarrantsExercisableRollForward"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights_da7a9035-48cf-4f97-9012-9277a7855023" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:to="loc_cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights_da7a9035-48cf-4f97-9012-9277a7855023" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_0e66a327-36d2-462a-b78c-cf6d6d95df06" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:to="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsGrantedDuringPeriod_0e66a327-36d2-462a-b78c-cf6d6d95df06" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_a51df591-6ed9-4591-8bce-a36f9c42567a" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:to="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsExercisedDuringPeriod_a51df591-6ed9-4591-8bce-a36f9c42567a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsCancelledorExpiredDuringPeriod_055b40e6-983f-4890-b3ab-ab861a2df0ee" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsCancelledorExpiredDuringPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:to="loc_cfms_ClassofWarrantorRightNumberofExercisableSecuritiesCalledbyWarrantsorRightsCancelledorExpiredDuringPeriod_055b40e6-983f-4890-b3ab-ab861a2df0ee" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights_5ca31552-3cca-4cdc-976f-176978ffca28" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsNumberofWarrantsExercisableRollForward_d5739c04-af32-4082-9a2b-c944d8f365ba" xlink:to="loc_cfms_ClassofWarrantorRightNumberofSecuritiesAvailabletoCallbyWarrantsorRights_5ca31552-3cca-4cdc-976f-176978ffca28" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:href="cfms-20230331.xsd#cfms_StockWarrantsWeightedAveragePricePerShareRollForward"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding_4cec89a2-3f5b-44f7-baa8-885a47e58259" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:to="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding_4cec89a2-3f5b-44f7-baa8-885a47e58259" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsGrantedDuringPeriod_397990c2-f599-48ec-b39f-57c78a4338af" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightPriceofWarrantsorRightsGrantedDuringPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:to="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsGrantedDuringPeriod_397990c2-f599-48ec-b39f-57c78a4338af" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsExercisedDuringPeriod_473ce2a6-7480-492a-958a-6d5d7f6211dd" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightPriceofWarrantsorRightsExercisedDuringPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:to="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsExercisedDuringPeriod_473ce2a6-7480-492a-958a-6d5d7f6211dd" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsCancelledorExpiredDuringPeriod_26a9d934-96e9-452e-b99f-172eed933ad6" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightPriceofWarrantsorRightsCancelledorExpiredDuringPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:to="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsCancelledorExpiredDuringPeriod_26a9d934-96e9-452e-b99f-172eed933ad6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding_474c5312-7ac7-42d7-90e7-bceedf77e777" xlink:href="cfms-20230331.xsd#cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_cfms_StockWarrantsWeightedAveragePricePerShareRollForward_d179bdc9-a68c-48d1-a558-abb5de08a39c" xlink:to="loc_cfms_ClassofWarrantorRightPriceofWarrantsorRightsOutstanding_474c5312-7ac7-42d7-90e7-bceedf77e777" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_42b80a2a-f065-4b12-89c3-1c99ccd711e0" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ClassOfWarrantOrRightLineItems_169c0cac-30d6-4a97-ab4e-b1d51897b4c3" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_42b80a2a-f065-4b12-89c3-1c99ccd711e0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityStockOptionPlansNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityStockOptionPlansNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityStockOptionPlansNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_ee3d87f2-5d48-4f18-b2a0-5b4c5ffb5ac2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_9d81ef57-f526-409e-896e-7a4d08b6f2c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_ee3d87f2-5d48-4f18-b2a0-5b4c5ffb5ac2" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_9d81ef57-f526-409e-896e-7a4d08b6f2c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameAxis_65b51ace-4f84-4958-806b-cbff0a02772a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_9d81ef57-f526-409e-896e-7a4d08b6f2c8" xlink:to="loc_us-gaap_PlanNameAxis_65b51ace-4f84-4958-806b-cbff0a02772a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PlanNameDomain_c84d7da9-b256-4a1f-9ec3-43e811520802" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameAxis_65b51ace-4f84-4958-806b-cbff0a02772a" xlink:to="loc_us-gaap_PlanNameDomain_c84d7da9-b256-4a1f-9ec3-43e811520802" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_EquityIncentivePlan2015Member_c5740f25-7233-456c-9ac0-58a7307ce707" xlink:href="cfms-20230331.xsd#cfms_EquityIncentivePlan2015Member"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_c84d7da9-b256-4a1f-9ec3-43e811520802" xlink:to="loc_cfms_EquityIncentivePlan2015Member_c5740f25-7233-456c-9ac0-58a7307ce707" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_A2019SalesTeamPlanMember_08a440d4-624c-4ca1-909f-641f7de31992" xlink:href="cfms-20230331.xsd#cfms_A2019SalesTeamPlanMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_PlanNameDomain_c84d7da9-b256-4a1f-9ec3-43e811520802" xlink:to="loc_cfms_A2019SalesTeamPlanMember_08a440d4-624c-4ca1-909f-641f7de31992" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_2381f15c-8166-42f5-a335-c4898b01bc47" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_9d81ef57-f526-409e-896e-7a4d08b6f2c8" xlink:to="loc_us-gaap_AwardTypeAxis_2381f15c-8166-42f5-a335-c4898b01bc47" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_feeb9c91-0026-4798-9fb4-ca9963d6b2bc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_2381f15c-8166-42f5-a335-c4898b01bc47" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_feeb9c91-0026-4798-9fb4-ca9963d6b2bc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CommonStockMember_dfcd0214-92fb-448b-bf78-2011e335f106" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CommonStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_feeb9c91-0026-4798-9fb4-ca9963d6b2bc" xlink:to="loc_us-gaap_CommonStockMember_dfcd0214-92fb-448b-bf78-2011e335f106" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_7a2ebf86-aa65-4c58-a233-e00ca86cd9d2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_feeb9c91-0026-4798-9fb4-ca9963d6b2bc" xlink:to="loc_us-gaap_RestrictedStockMember_7a2ebf86-aa65-4c58-a233-e00ca86cd9d2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_9d81ef57-f526-409e-896e-7a4d08b6f2c8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualAmount_b326f3a3-afc9-4828-890a-b48938addefb" xlink:href="cfms-20230331.xsd#cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualAmount"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualAmount_b326f3a3-afc9-4828-890a-b48938addefb" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualPercentage_29128688-b342-44ad-8da8-65b24b7fc3b0" xlink:href="cfms-20230331.xsd#cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualPercentage"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_cfms_ShareBasedCompensationArrangementByShareBasedPaymentAwardAdditionalSharesAuthorizedMaximumAnnualPercentage_29128688-b342-44ad-8da8-65b24b7fc3b0" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_3773831f-7dd7-42fa-adb9-9af3c8403dfa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_3773831f-7dd7-42fa-adb9-9af3c8403dfa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_8732a983-ea3c-49bf-927b-675f21de1224" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAvailableForGrant_8732a983-ea3c-49bf-927b-675f21de1224" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_b1a9ecfa-ddb1-41e4-9e29-daad7008ca5e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardNumberOfSharesAuthorized_b1a9ecfa-ddb1-41e4-9e29-daad7008ca5e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_21d46dda-5e68-43a3-8e6c-aba72d877e40" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardExpirationPeriod_21d46dda-5e68-43a3-8e6c-aba72d877e40" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_b31f0623-d131-409b-ab14-cab104d99804" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="7" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_b31f0623-d131-409b-ab14-cab104d99804" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_55c4ab12-d165-42a1-bd8e-d937857f7e7d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1"/>
    <link:presentationArc order="8" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsVestedInPeriodFairValue1_55c4ab12-d165-42a1-bd8e-d937857f7e7d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_5f40ddf5-e3f3-43eb-b867-09e2e54137fa" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2"/>
    <link:presentationArc order="9" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsOutstandingWeightedAverageRemainingContractualTerm2_5f40ddf5-e3f3-43eb-b867-09e2e54137fa" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_44c2bf30-99f8-4321-a6c2-ff5d65b439c2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1"/>
    <link:presentationArc order="10" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_587e1a30-7b48-4e74-adb2-de53e398db85" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableWeightedAverageRemainingContractualTerm1_44c2bf30-99f8-4321-a6c2-ff5d65b439c2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityStockOptionPlansDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityStockOptionPlansDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityStockOptionPlansDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_a4472687-22b1-434f-b92a-6b045852cd2f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_bbb568ba-fd1c-4d6f-9c2c-80fb4e8227e5" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_a4472687-22b1-434f-b92a-6b045852cd2f" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_bbb568ba-fd1c-4d6f-9c2c-80fb4e8227e5" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_1d0dbdb5-550e-4704-9098-b395280b61df" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_bbb568ba-fd1c-4d6f-9c2c-80fb4e8227e5" xlink:to="loc_us-gaap_AwardTypeAxis_1d0dbdb5-550e-4704-9098-b395280b61df" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cc347048-130e-4cf2-b232-8dd324208760" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_1d0dbdb5-550e-4704-9098-b395280b61df" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cc347048-130e-4cf2-b232-8dd324208760" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_EmployeeDirectorAndConsultantStockOptionsMember_41d98653-7437-445a-a119-ace209788137" xlink:href="cfms-20230331.xsd#cfms_EmployeeDirectorAndConsultantStockOptionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_cc347048-130e-4cf2-b232-8dd324208760" xlink:to="loc_cfms_EmployeeDirectorAndConsultantStockOptionsMember_41d98653-7437-445a-a119-ace209788137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_bbb568ba-fd1c-4d6f-9c2c-80fb4e8227e5" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e66e4a8e-e9e6-4e5b-9ebb-12a9c654ae18" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e66e4a8e-e9e6-4e5b-9ebb-12a9c654ae18" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8cc13329-b376-4ac3-83d8-0adb3f3a3b5a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_8cc13329-b376-4ac3-83d8-0adb3f3a3b5a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_1ad659ed-84ba-49b2-9d1b-d337c4ec3d54" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExpirationsInPeriod_1ad659ed-84ba-49b2-9d1b-d337c4ec3d54" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_4e3bd064-1003-4b39-a398-bd2be5409238" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsForfeituresInPeriod_4e3bd064-1003-4b39-a398-bd2be5409238" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e9284e6b-5aa2-4bd7-bd20-5de76a9d7b0e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingRollForward_39f756e2-c2d2-4e50-8dad-203a28e2f47e" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingNumber_e9284e6b-5aa2-4bd7-bd20-5de76a9d7b0e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_d90f2ef5-a86a-4786-a9a0-0dd57036d3ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableNumber_d90f2ef5-a86a-4786-a9a0-0dd57036d3ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_624001ce-838c-49cb-b738-552696380248" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_624001ce-838c-49cb-b738-552696380248" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_e09bed52-53e6-4099-b5f1-b621b0366627" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_e09bed52-53e6-4099-b5f1-b621b0366627" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_628466bc-3ec9-462d-88ee-34006e22537b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsExpirationsInPeriodWeightedAverageExercisePrice_628466bc-3ec9-462d-88ee-34006e22537b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_0acbfd66-3f89-4155-9838-6d04de260726" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsForfeituresInPeriodWeightedAverageExercisePrice_0acbfd66-3f89-4155-9838-6d04de260726" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_13fcbee2-2b87-4f89-a24e-227f481439a2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePriceRollforward_5f405d07-16f2-4dfc-9e39-8a2ce51e78cc" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingWeightedAverageExercisePrice_13fcbee2-2b87-4f89-a24e-227f481439a2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_e7a7d699-71eb-4675-ae83-bfee5e3e4120" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsExercisableWeightedAverageExercisePrice_e7a7d699-71eb-4675-ae83-bfee5e3e4120" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_91beb3a4-e6db-4ab9-8016-8f7969baa4e4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_91beb3a4-e6db-4ab9-8016-8f7969baa4e4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_b1a7814f-0f3b-471e-9bf6-5f1a7094ac55" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_91beb3a4-e6db-4ab9-8016-8f7969baa4e4" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsOutstandingIntrinsicValue_b1a7814f-0f3b-471e-9bf6-5f1a7094ac55" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_8f9aae65-9689-47ad-abca-8a31e3354e37" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsAdditionalDisclosuresAbstract_91beb3a4-e6db-4ab9-8016-8f7969baa4e4" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardOptionsExercisableIntrinsicValue1_8f9aae65-9689-47ad-abca-8a31e3354e37" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_565839aa-3cbc-4cff-835c-591050ef3959" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="6" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_35959cfe-86e9-4292-bed3-0aa1da8b0289" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_565839aa-3cbc-4cff-835c-591050ef3959" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityScheduleofRestrictedCommonStockAwardActivityDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityScheduleofRestrictedCommonStockAwardActivityDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityScheduleofRestrictedCommonStockAwardActivityDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_c6c4b114-5e0a-47e8-880e-aa043146399c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_eaf2d47d-7d59-4a02-b7e9-951ac6977f9b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_c6c4b114-5e0a-47e8-880e-aa043146399c" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_eaf2d47d-7d59-4a02-b7e9-951ac6977f9b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_c94b68c9-8c87-4823-9787-df1a3cef8af2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_eaf2d47d-7d59-4a02-b7e9-951ac6977f9b" xlink:to="loc_us-gaap_AwardTypeAxis_c94b68c9-8c87-4823-9787-df1a3cef8af2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7697f635-3c4c-4b02-ab30-7cb776a8b0ca" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_c94b68c9-8c87-4823-9787-df1a3cef8af2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7697f635-3c4c-4b02-ab30-7cb776a8b0ca" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_53d7a22b-3f2a-453b-97b6-bba83db9e06c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_7697f635-3c4c-4b02-ab30-7cb776a8b0ca" xlink:to="loc_us-gaap_RestrictedStockMember_53d7a22b-3f2a-453b-97b6-bba83db9e06c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_135b5f1a-2c42-45cd-acac-a7f9ad241c77" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_eaf2d47d-7d59-4a02-b7e9-951ac6977f9b" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_135b5f1a-2c42-45cd-acac-a7f9ad241c77" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_135b5f1a-2c42-45cd-acac-a7f9ad241c77" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_0a174c44-d56a-4802-bfd3-d281c8a754a3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_0a174c44-d56a-4802-bfd3-d281c8a754a3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_4883fe76-3eb2-4774-b81a-b9bbae78c280" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_4883fe76-3eb2-4774-b81a-b9bbae78c280" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_00d08689-5fd9-4492-9734-f20796829509" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriod_00d08689-5fd9-4492-9734-f20796829509" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_725b7d8c-2261-45da-98d2-b43dff6b1096" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeitedInPeriod_725b7d8c-2261-45da-98d2-b43dff6b1096" xlink:type="arc" preferredLabel="http://www.xbrl.org/2009/role/negatedTerseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_10858ab5-4b8d-452c-8518-9367a03798f1" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedRollForward_33946155-5697-4304-9f1e-02d4a46448ba" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedNumber_10858ab5-4b8d-452c-8518-9367a03798f1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_135b5f1a-2c42-45cd-acac-a7f9ad241c77" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_31ea2152-a8e8-4bac-92ba-5611e79d792a" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_31ea2152-a8e8-4bac-92ba-5611e79d792a" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodStartLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_d21bc9d9-6a82-484f-8bbc-72a0a01c4dba" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriodWeightedAverageGrantDateFairValue_d21bc9d9-6a82-484f-8bbc-72a0a01c4dba" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_a69aeec5-106e-4168-b37e-e12fa1edc26f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsVestedInPeriodWeightedAverageGrantDateFairValue_a69aeec5-106e-4168-b37e-e12fa1edc26f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_87556cc1-d6e3-4327-abcf-64f54c1fa564" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsForfeituresWeightedAverageGrantDateFairValue_87556cc1-d6e3-4327-abcf-64f54c1fa564" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_81f8e20b-70ab-4d79-a19a-21a90b13a20d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue"/>
    <link:presentationArc order="5" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValueRollForward_cd68e46e-b9aa-4917-aac2-df010468e3e9" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsNonvestedWeightedAverageGrantDateFairValue_81f8e20b-70ab-4d79-a19a-21a90b13a20d" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/periodEndLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_683baabd-f1fd-4e10-8e17-c59a6e3e111f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_135b5f1a-2c42-45cd-acac-a7f9ad241c77" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_683baabd-f1fd-4e10-8e17-c59a6e3e111f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityInducementAwardsDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityInducementAwardsDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityInducementAwardsDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_f74f0707-805c-402f-88c3-a3481c5e36b6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_796d2d2a-1bc3-4feb-9259-1e8f44d40ff2" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_f74f0707-805c-402f-88c3-a3481c5e36b6" xlink:to="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_796d2d2a-1bc3-4feb-9259-1e8f44d40ff2" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_TitleOfIndividualAxis_b8eeba31-f8ee-497b-9741-13cd0affa805" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_TitleOfIndividualAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_796d2d2a-1bc3-4feb-9259-1e8f44d40ff2" xlink:to="loc_srt_TitleOfIndividualAxis_b8eeba31-f8ee-497b-9741-13cd0affa805" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_7644588d-cb90-460a-bbc3-18ed2efaf9ab" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_TitleOfIndividualWithRelationshipToEntityDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualAxis_b8eeba31-f8ee-497b-9741-13cd0affa805" xlink:to="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_7644588d-cb90-460a-bbc3-18ed2efaf9ab" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ChiefFinancialOfficerMember_9e2637de-d48d-4e4a-9a0a-54cdf1385ca9" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ChiefFinancialOfficerMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_7644588d-cb90-460a-bbc3-18ed2efaf9ab" xlink:to="loc_srt_ChiefFinancialOfficerMember_9e2637de-d48d-4e4a-9a0a-54cdf1385ca9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_VicePresidentInternationalSalesAndMarketingMember_5608754f-d02a-4058-8398-d51523deeb75" xlink:href="cfms-20230331.xsd#cfms_VicePresidentInternationalSalesAndMarketingMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_7644588d-cb90-460a-bbc3-18ed2efaf9ab" xlink:to="loc_cfms_VicePresidentInternationalSalesAndMarketingMember_5608754f-d02a-4058-8398-d51523deeb75" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ChiefOperatingOfficerMember_381e7652-8302-468e-8d56-1996aa2cffcf" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ChiefOperatingOfficerMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_TitleOfIndividualWithRelationshipToEntityDomain_7644588d-cb90-460a-bbc3-18ed2efaf9ab" xlink:to="loc_srt_ChiefOperatingOfficerMember_381e7652-8302-468e-8d56-1996aa2cffcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_86595d66-fe8b-4cb6-a15b-48102d7f729c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_796d2d2a-1bc3-4feb-9259-1e8f44d40ff2" xlink:to="loc_us-gaap_AwardTypeAxis_86595d66-fe8b-4cb6-a15b-48102d7f729c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5ce66bdd-255d-464c-af3d-1e37cb750075" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_86595d66-fe8b-4cb6-a15b-48102d7f729c" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5ce66bdd-255d-464c-af3d-1e37cb750075" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_InducementAwardMember_6a9b95e9-0cbe-464f-83e5-49032165efae" xlink:href="cfms-20230331.xsd#cfms_InducementAwardMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5ce66bdd-255d-464c-af3d-1e37cb750075" xlink:to="loc_cfms_InducementAwardMember_6a9b95e9-0cbe-464f-83e5-49032165efae" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_1fd11027-80cb-4c5a-9375-3b6aa95e8a44" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_5ce66bdd-255d-464c-af3d-1e37cb750075" xlink:to="loc_us-gaap_RestrictedStockMember_1fd11027-80cb-4c5a-9375-3b6aa95e8a44" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfShareBasedCompensationArrangementsByShareBasedPaymentAwardTable_796d2d2a-1bc3-4feb-9259-1e8f44d40ff2" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_a41c22c1-4f81-439b-ad7a-0fe84b5b117b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardOptionsGrantsInPeriodGross_a41c22c1-4f81-439b-ad7a-0fe84b5b117b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_fa699994-c930-4907-8479-a1b838bd12ad" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardOptionsGrantsInPeriodWeightedAverageExercisePrice_fa699994-c930-4907-8479-a1b838bd12ad" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_f6161e0c-d4e9-45d0-a9cc-1bb1758d8ef6" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardEquityInstrumentsOtherThanOptionsGrantsInPeriod_f6161e0c-d4e9-45d0-a9cc-1bb1758d8ef6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_e11f11db-723a-4c4c-8b01-455d4e6cefcf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_StockholdersEquityNoteStockSplitConversionRatio1"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardLineItems_f33d8fec-0355-4db1-87da-c6a7eb39e5da" xlink:to="loc_us-gaap_StockholdersEquityNoteStockSplitConversionRatio1_e11f11db-723a-4c4c-8b01-455d4e6cefcf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityStockbasedCompensationDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityStockbasedCompensationDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityStockbasedCompensationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_56d65946-84b2-4497-bcff-16f77fbfa805" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_cbbacc0e-b1fd-4117-a79a-a0fc79309500" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_56d65946-84b2-4497-bcff-16f77fbfa805" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsRiskFreeInterestRate_cbbacc0e-b1fd-4117-a79a-a0fc79309500" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_4247282c-077d-497f-9506-28af40fb867c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_56d65946-84b2-4497-bcff-16f77fbfa805" xlink:to="loc_us-gaap_SharebasedCompensationArrangementBySharebasedPaymentAwardFairValueAssumptionsExpectedTerm1_4247282c-077d-497f-9506-28af40fb867c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_3e1cb142-7a03-43bf-b9f4-bc3dbabf96cf" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_56d65946-84b2-4497-bcff-16f77fbfa805" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedDividendRate_3e1cb142-7a03-43bf-b9f4-bc3dbabf96cf" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_7445bf26-1203-4026-9f4f-c5ffa2b59156" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_56d65946-84b2-4497-bcff-16f77fbfa805" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementByShareBasedPaymentAwardFairValueAssumptionsExpectedVolatilityRate_7445bf26-1203-4026-9f4f-c5ffa2b59156" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquityStockbasedCompensationNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquityStockbasedCompensationNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquityStockbasedCompensationNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_a94a3ca5-75e4-4d95-bbbc-f9ad9685250d" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_8deb9cac-7d94-4ecb-ba7e-ad1ee4fd4c93" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_a94a3ca5-75e4-4d95-bbbc-f9ad9685250d" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_8deb9cac-7d94-4ecb-ba7e-ad1ee4fd4c93" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AwardTypeAxis_912f7dee-f40d-4072-b970-e30fc45ba0c8" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AwardTypeAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_8deb9cac-7d94-4ecb-ba7e-ad1ee4fd4c93" xlink:to="loc_us-gaap_AwardTypeAxis_912f7dee-f40d-4072-b970-e30fc45ba0c8" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_37945a5b-3df1-4964-9678-314927c8f3a9" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_AwardTypeAxis_912f7dee-f40d-4072-b970-e30fc45ba0c8" xlink:to="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_37945a5b-3df1-4964-9678-314927c8f3a9" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_EmployeeDirectorAndConsultantStockOptionsMember_48753cff-cc79-4ba4-aba9-27ad2fc6d047" xlink:href="cfms-20230331.xsd#cfms_EmployeeDirectorAndConsultantStockOptionsMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_37945a5b-3df1-4964-9678-314927c8f3a9" xlink:to="loc_cfms_EmployeeDirectorAndConsultantStockOptionsMember_48753cff-cc79-4ba4-aba9-27ad2fc6d047" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RestrictedStockMember_ac03b4c3-e2d2-45ab-96f1-fa90889ddcc3" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RestrictedStockMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ShareBasedCompensationArrangementsByShareBasedPaymentAwardAwardTypeAndPlanNameDomain_37945a5b-3df1-4964-9678-314927c8f3a9" xlink:to="loc_us-gaap_RestrictedStockMember_ac03b4c3-e2d2-45ab-96f1-fa90889ddcc3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_25d3a33a-8e8b-4401-a087-d2767ff592d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_8deb9cac-7d94-4ecb-ba7e-ad1ee4fd4c93" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_25d3a33a-8e8b-4401-a087-d2767ff592d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_0d5ce5a4-afa1-4dd3-be31-dcdebf1b39b7" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_25d3a33a-8e8b-4401-a087-d2767ff592d4" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_0d5ce5a4-afa1-4dd3-be31-dcdebf1b39b7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_e20d9f3e-59ab-45ef-8689-1b78545251d4" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_25d3a33a-8e8b-4401-a087-d2767ff592d4" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognized_e20d9f3e-59ab-45ef-8689-1b78545251d4" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_a8c8e9b1-8988-48b3-b598-5a974b2be159" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_25d3a33a-8e8b-4401-a087-d2767ff592d4" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationNonvestedAwardsTotalCompensationCostNotYetRecognizedPeriodForRecognition1_a8c8e9b1-8988-48b3-b598-5a974b2be159" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/StockholdersEquitySummaryofStockbasedCompensationDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#StockholdersEquitySummaryofStockbasedCompensationDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/StockholdersEquitySummaryofStockbasedCompensationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EquityAbstract_1dddddcd-f8f1-4da4-9070-201d04d418bd" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EquityAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_b306d430-bf27-45b6-8127-3100efd4f001" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EquityAbstract_1dddddcd-f8f1-4da4-9070-201d04d418bd" xlink:to="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_b306d430-bf27-45b6-8127-3100efd4f001" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationAxis_cdc68932-a95f-4b3b-842f-f9c88c8f8f1f" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementLocationAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_b306d430-bf27-45b6-8127-3100efd4f001" xlink:to="loc_us-gaap_IncomeStatementLocationAxis_cdc68932-a95f-4b3b-842f-f9c88c8f8f1f" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_IncomeStatementLocationDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationAxis_cdc68932-a95f-4b3b-842f-f9c88c8f8f1f" xlink:to="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_CostOfSalesMember_ccf7e20c-7abc-4eae-bd9d-e3ea9280a394" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_CostOfSalesMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:to="loc_us-gaap_CostOfSalesMember_ccf7e20c-7abc-4eae-bd9d-e3ea9280a394" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SellingAndMarketingExpenseMember_e057ee61-0280-4aeb-90e6-4988c5f33e87" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SellingAndMarketingExpenseMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:to="loc_us-gaap_SellingAndMarketingExpenseMember_e057ee61-0280-4aeb-90e6-4988c5f33e87" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ResearchAndDevelopmentExpenseMember_08a90b94-c4bd-4f26-9956-1cd4a018c880" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ResearchAndDevelopmentExpenseMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:to="loc_us-gaap_ResearchAndDevelopmentExpenseMember_08a90b94-c4bd-4f26-9956-1cd4a018c880" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_GeneralAndAdministrativeExpenseMember_6d383873-35f7-4c50-95de-dc430557f994" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_GeneralAndAdministrativeExpenseMember"/>
    <link:presentationArc order="4" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_IncomeStatementLocationDomain_ac7279b5-df6f-4437-812f-b59542bcf226" xlink:to="loc_us-gaap_GeneralAndAdministrativeExpenseMember_6d383873-35f7-4c50-95de-dc430557f994" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_bac7d341-5a40-4025-badf-bbbb60676a0c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfEmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsTable_b306d430-bf27-45b6-8127-3100efd4f001" xlink:to="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_bac7d341-5a40-4025-badf-bbbb60676a0c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_AllocatedShareBasedCompensationExpense_a8759b76-3426-4cbf-9e21-98d1d7efc89e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_AllocatedShareBasedCompensationExpense"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_EmployeeServiceShareBasedCompensationAllocationOfRecognizedPeriodCostsLineItems_bac7d341-5a40-4025-badf-bbbb60676a0c" xlink:to="loc_us-gaap_AllocatedShareBasedCompensationExpense_a8759b76-3426-4cbf-9e21-98d1d7efc89e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SegmentandGeographicDataNarrativeDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SegmentandGeographicDataNarrativeDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SegmentandGeographicDataNarrativeDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_c75cb428-c836-467d-b7da-35b721ea5623" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NumberOfReportableSegments_8620fef1-252a-4480-842b-79642ae8f786" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NumberOfReportableSegments"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_c75cb428-c836-467d-b7da-35b721ea5623" xlink:to="loc_us-gaap_NumberOfReportableSegments_8620fef1-252a-4480-842b-79642ae8f786" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
  <link:roleRef roleURI="http://www.conformis.com/role/SegmentandGeographicDataGeographicandProductCategoryInformationDetails" xlink:type="simple" xlink:href="cfms-20230331.xsd#SegmentandGeographicDataGeographicandProductCategoryInformationDetails"/>
  <link:presentationLink xlink:role="http://www.conformis.com/role/SegmentandGeographicDataGeographicandProductCategoryInformationDetails" xlink:type="extended">
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_SegmentReportingAbstract_a40ba7e1-d047-48a5-85d5-efdf4260c22e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_SegmentReportingAbstract"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_d4984858-5618-46ab-b4f7-dd0b4391c363" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_SegmentReportingAbstract_a40ba7e1-d047-48a5-85d5-efdf4260c22e" xlink:to="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_d4984858-5618-46ab-b4f7-dd0b4391c363" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductOrServiceAxis_dfa36ba9-db30-4328-92a3-a0d15a0af090" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductOrServiceAxis"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_d4984858-5618-46ab-b4f7-dd0b4391c363" xlink:to="loc_srt_ProductOrServiceAxis_dfa36ba9-db30-4328-92a3-a0d15a0af090" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_ProductsAndServicesDomain_fb053000-903d-4e3c-801a-11a1050d8af7" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_ProductsAndServicesDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductOrServiceAxis_dfa36ba9-db30-4328-92a3-a0d15a0af090" xlink:to="loc_srt_ProductsAndServicesDomain_fb053000-903d-4e3c-801a-11a1050d8af7" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_ProductMember_d477302a-0797-4f01-855b-757fd518a76c" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_ProductMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_ProductsAndServicesDomain_fb053000-903d-4e3c-801a-11a1050d8af7" xlink:to="loc_us-gaap_ProductMember_d477302a-0797-4f01-855b-757fd518a76c" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_KneeMember_1d8db15c-8d65-4da1-a5f0-34312d9f9bef" xlink:href="cfms-20230331.xsd#cfms_KneeMember"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_d477302a-0797-4f01-855b-757fd518a76c" xlink:to="loc_cfms_KneeMember_1d8db15c-8d65-4da1-a5f0-34312d9f9bef" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_cfms_HipMember_861b0464-af9b-4adc-a59e-7aa2008831d1" xlink:href="cfms-20230331.xsd#cfms_HipMember"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ProductMember_d477302a-0797-4f01-855b-757fd518a76c" xlink:to="loc_cfms_HipMember_861b0464-af9b-4adc-a59e-7aa2008831d1" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_StatementGeographicalAxis_24a283a3-c99f-42ea-8db1-3c53c8f76137" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_StatementGeographicalAxis"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_d4984858-5618-46ab-b4f7-dd0b4391c363" xlink:to="loc_srt_StatementGeographicalAxis_24a283a3-c99f-42ea-8db1-3c53c8f76137" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_srt_SegmentGeographicalDomain_9e775c9c-842a-4292-9c23-7faecc3f6a5b" xlink:href="https://xbrl.fasb.org/srt/2022/elts/srt-2022.xsd#srt_SegmentGeographicalDomain"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_StatementGeographicalAxis_24a283a3-c99f-42ea-8db1-3c53c8f76137" xlink:to="loc_srt_SegmentGeographicalDomain_9e775c9c-842a-4292-9c23-7faecc3f6a5b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_US_12e64f52-61bc-4acf-aec8-36b5dfe9eaf6" xlink:href="https://xbrl.sec.gov/country/2022/country-2022.xsd#country_US"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_9e775c9c-842a-4292-9c23-7faecc3f6a5b" xlink:to="loc_country_US_12e64f52-61bc-4acf-aec8-36b5dfe9eaf6" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_country_DE_5c07d97d-c0ca-47ba-a43e-79d4421656f3" xlink:href="https://xbrl.sec.gov/country/2022/country-2022.xsd#country_DE"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_9e775c9c-842a-4292-9c23-7faecc3f6a5b" xlink:to="loc_country_DE_5c07d97d-c0ca-47ba-a43e-79d4421656f3" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_NonUsMember_dbb9b2d7-136b-4280-9528-a097cbe63352" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_NonUsMember"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_srt_SegmentGeographicalDomain_9e775c9c-842a-4292-9c23-7faecc3f6a5b" xlink:to="loc_us-gaap_NonUsMember_dbb9b2d7-136b-4280-9528-a097cbe63352" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_59efd8f2-6007-496b-99d7-49f8290cd11e" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems"/>
    <link:presentationArc order="3" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_ScheduleOfRevenuesFromExternalCustomersAndLongLivedAssetsTable_d4984858-5618-46ab-b4f7-dd0b4391c363" xlink:to="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_59efd8f2-6007-496b-99d7-49f8290cd11e" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_7b417eb9-e162-4790-97fe-4483f423c68b" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax"/>
    <link:presentationArc order="1" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_59efd8f2-6007-496b-99d7-49f8290cd11e" xlink:to="loc_us-gaap_RevenueFromContractWithCustomerExcludingAssessedTax_7b417eb9-e162-4790-97fe-4483f423c68b" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/verboseLabel"/>
    <link:loc xlink:type="locator" xlink:label="loc_us-gaap_PropertyPlantAndEquipmentNet_4bd15784-29bb-44e0-9e8e-54c128392d15" xlink:href="https://xbrl.fasb.org/us-gaap/2022/elts/us-gaap-2022.xsd#us-gaap_PropertyPlantAndEquipmentNet"/>
    <link:presentationArc order="2" xlink:arcrole="http://www.xbrl.org/2003/arcrole/parent-child" xlink:from="loc_us-gaap_RevenuesFromExternalCustomersAndLongLivedAssetsLineItems_59efd8f2-6007-496b-99d7-49f8290cd11e" xlink:to="loc_us-gaap_PropertyPlantAndEquipmentNet_4bd15784-29bb-44e0-9e8e-54c128392d15" xlink:type="arc" preferredLabel="http://www.xbrl.org/2003/role/terseLabel"/>
  </link:presentationLink>
</link:linkbase>
