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Organization and Basis of Presentation (Details)
$ in Thousands
3 Months Ended
Oct. 26, 2022
shares
Nov. 22, 2021
USD ($)
Mar. 31, 2023
USD ($)
shares
Mar. 31, 2022
Dec. 31, 2022
USD ($)
shares
Mar. 30, 2021
shares
Mar. 29, 2021
shares
Line of Credit Facility [Line Items]              
Accumulated deficit     $ 590,895   $ 581,324    
Cash and cash equivalents and investments     37,800        
Restricted cash     $ 462   $ 462    
Stock split, conversion ratio 0.04   0.04 0.04      
Common stock, shares authorized (in shares) | shares 20,000,000   20,000,000   20,000,000 300,000,000 200,000,000
Term Loan | MidCap Financial Services, LLC Term Loan | MidCap Financial Services, LLC              
Line of Credit Facility [Line Items]              
Credit facility term   5 years          
Debt instrument principal   $ 21,000