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Consolidated Statements of Operations - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2016
Dec. 31, 2015
Dec. 31, 2014
Operating expenses:      
Research and development $ 33,014 $ 8,117 $ 644
General and administrative 13,106 4,855 872
Total operating expenses 46,120 12,972 1,516
Loss from operations (46,120) (12,972) (1,516)
Interest expense (690) (350)  
Other expense, net (277)    
Net loss $ (47,087) $ (13,322) $ (1,516)
Net loss per share, basic and diluted $ (7.84) $ (62.19) $ (7.82)
Weighted-average common shares outstanding, basic and diluted 6,007,027 214,228 193,850