Condensed Consolidated Statements of Stockholders' Equity (Deficit) - 6 months ended Jun. 30, 2016 - USD ($) $ in Thousands	Total	Convertible Preferred Stock [Member]	Eiccose LLC [Member]	Common Stock [Member]	Common Stock [Member] Eiccose LLC [Member]	Additional Paid-in Capital [Member]	Additional Paid-in Capital [Member] Eiccose LLC [Member]	Accumulated Deficit [Member]
Beginning Balance at Dec. 31, 2015	$ (5,152)					$ 1,552		$ (29,271)
Temporary equity, Beginning balance at Dec. 31, 2015		$ 22,567
Beginning Balance, Shares at Dec. 31, 2015	273,993			273,993
Temporary equity, Beginning balance, Shares at Dec. 31, 2015		2,609,102
Issuance of common stock upon private placement, net of issuance cost	$ 32,108			$ 2		32,106
Issuance of common stock upon private placement, net of issuance costs, Shares				1,954,390
Conversion of preferred stock into common stock, Temporary equity value	6,129	$ (22,567)				6,129
Issuance of common stock upon conversion of convertible promissory note, Shares				350,040
Conversion of preferred stock into common stock, Temporary equity shares		(2,609,102)
Issuance of common stock upon exercise of warrants	1,057					1,057
Issuance of common stock upon exercise of warrants, Shares				61,254
Issuance of common stock to Eiccose upon private placement			$ 1,661				$ 1,661
Issuance of common stock to Eiccose upon private placement, Shares					96,300
Conversion of preferred stock into common stock				$ 3		22,564
Conversion of preferred stock into common stock, Shares				2,609,102
Issuance of common stock upon reverse merger	27,390			$ 2		27,388
Issuance of common stock upon reverse merger, Shares				1,596,959
Issuance of common stock upon execution of license agreement	3,172					3,172
Issuance of common stock upon execution of license agreement, Shares				157,587
Issuance of common stock upon exercise of options	$ 39					39
Issuance of common stock upon exercise of options, Shares	7,034			7,034
Stock-based compensation expense	$ 512					512
Net loss	(22,949)							(22,949)
Ending Balance at Jun. 30, 2016	$ 43,967			$ 7		$ 96,180		$ (52,220)
Ending Balance, Shares at Jun. 30, 2016	7,106,659			7,106,659