Fiduciary/Claymore MLP Opportunity Fund

2455 Corporate West Drive

Lisle, Illinois 60532

April 28, 2011

Richard Pfordte

Kimberly A. Browning

Securities and Exchange Commission

Office of Investment Management

100 F Street, NE

Washington, DC  20549

Re: Fiduciary/Claymore MLP Opportunity Fund – Registration

                                               Statement on Form N-2 (File Nos. 333-172885 & 811-21652)

Dear Sir and Madam:

In accordance with Rule 461 of the General Rules and Regulations under the Securities Act of 1933, as amended, Fiduciary/Claymore MLP Opportunity Fund hereby requests acceleration of the effective date of the above-captioned Registration Statement so that it may become effective at 11:00 a.m., Eastern time, on Monday, May 2, 2011, or as soon as practical thereafter.

Sincerely,

FIDUCIARY/CLAYMORE MLP OPPORTUNITY FUND

By:        /s/ Mark E. Mathiasen                                                                   

  Mark E. Mathiasen

              Secretary