X0306 4 2022-02-03 0 0001339970 aTYR PHARMA INC LIFE 0001305178 Broadfoot Jill Marie 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO CA 92121 0 1 0 0 Chief Financial Officer Employee Stock Option (right to buy) 5.52 2022-02-03 4 A 0 30000 0.00 A 2032-02-03 Common Stock 30000 30000 D Restricted Stock Units 2022-02-03 4 A 0 15000 0.00 A Common Stock 15000 15000 D The shares subject to this option shall vest and become exercisable in 48 equal monthly installments beginning March 3, 2022, such that this option will be fully exercisable on February 3, 2026. This option is subject to accelerated vesting upon termination without cause upon change of control of the issuer. Each restricted stock unit (RSU) represents a contingent right to receive one share of the Issuer's common stock. The RSUs are scheduled to vest in four equal annual installments beginning on February 3, 2023, such that the RSUs will fully vest on February 3, 2026. This grant is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. Nancy E. Denyes, attorney-in-fact 2022-02-07