X0306 4 2018-07-30 0 0001339970 aTYR PHARMA INC LIFE 0001305178 Broadfoot Jill Marie 3545 JOHN HOPKINS COURT, SUITE 250 SAN DIEGO CA 92121 0 1 0 0 Chief Financial Officer Employee Stock Option (right to buy) 0.8151 2018-07-30 4 A 0 200000 0.00 A 2028-07-30 Common Stock 200000 200000 D 1/4 of the shares subject to this option shall vest and become exercisable on July 30, 2018, and the remainder shall thereafter vest and become exercisable in 36 equal monthly installments, such that this option will be fully exercisable on July 30, 2022. This option is subject to accelerated vesting upon termination without cause upon a change of control of the Issuer. Nancy D. Krueger, attorney-in-fact 2018-08-01