X0202 4 2007-05-22 0 0001012270 COLLAGENEX PHARMACEUTICALS INC CGPI 0001304113 Powell Andrew Kenneth William COLLAGENEX PHARMACEUTICALS, INC. 41 UNIVERSITY DRIVE, SUITE 200 NEWTOWN PA 18940 0 1 0 0 VP, G. Counsel and Corp. Sec. Common Stock 2007-05-22 4 P 0 200 10.48 A 2800 I By Trust Includes 700 shares held by the Uniform Trust for Minors Account for Mr. Powell's daughter and 500 shares are held by the Uniform Trust for Minors Account for Mr. Powell's son. /s/ Andrew K.W. Powell 2007-05-24