SEC Form 4

FORM 4		UNITED STATES SECURITIES AND EXCHANGE COMMISSION Washington, D.C. 20549 STATEMENT OF CHANGES IN BENEFICIAL OWNERSHIP Filed pursuant to Section 16(a) of the Securities Exchange Act of 1934 or Section 30(h) of the Investment Company Act of 1940	OMB APPROVAL OMB Number: 3235-0287 Estimated average burden hours per response: 0.5
	Check this box if no longer subject to Section 16. Form 4 or Form 5 obligations may continue. See Instruction 1(b).

1. Name and Address of Reporting Person* SIMON NICHOLAS J III (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR (Street) BOSTON MA 02116 (City) (State) (Zip)	2. Issuer Name and Ticker or Trading Symbol Pharmasset Inc [ VRUS ]	5. Relationship of Reporting Person(s) to Issuer (Check all applicable) Director X 10% Owner Officer (give title below) Other (specify below)
	3. Date of Earliest Transaction (Month/Day/Year) 02/04/2008
	4. If Amendment, Date of Original Filed (Month/Day/Year)	6. Individual or Joint/Group Filing (Check Applicable Line) Form filed by One Reporting Person X Form filed by More than One Reporting Person

Table I - Non-Derivative Securities Acquired, Disposed of, or Beneficially Owned
1. Title of Security (Instr. 3)	2. Transaction Date (Month/Day/Year)	2A. Deemed Execution Date, if any (Month/Day/Year)	3. Transaction Code (Instr. 8)		4. Securities Acquired (A) or Disposed Of (D) (Instr. 3, 4 and 5)			5. Amount of Securities Beneficially Owned Following Reported Transaction(s) (Instr. 3 and 4)	6. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	7. Nature of Indirect Beneficial Ownership (Instr. 4)
			Code	V	Amount	(A) or (D)	Price
Common Stock	02/04/2008		J(1)		713,912(2)	D	$0	1,261,782(3)	I	See Footnote(4)
Common Stock	02/04/2008		S		12,993(5)	D	$23.86	1,248,789	I	See Footnote(6)
Common Stock	02/04/2008		J(1)		10,936	A	$0	10,936	I	See Footnote(7)
Common Stock	02/04/2008		J(1)		5,390	A	$0	5,390	I	See Footnote(8)
Common Stock	02/04/2008		J(1)		5,117	A	$0	5,117	I	See Footnote(9)
Common Stock	02/04/2008		J(1)		10,935	A	$0	10,935	I	See Footnote(10)
Common Stock	02/04/2008		J(1)		68,295	A	$0	68,295	I	See Footnote(11)

Table II - Derivative Securities Acquired, Disposed of, or Beneficially Owned (e.g., puts, calls, warrants, options, convertible securities)
1. Title of Derivative Security (Instr. 3)	2. Conversion or Exercise Price of Derivative Security	3. Transaction Date (Month/Day/Year)	3A. Deemed Execution Date, if any (Month/Day/Year)	4. Transaction Code (Instr. 8)		5. Number of Derivative Securities Acquired (A) or Disposed of (D) (Instr. 3, 4 and 5)		6. Date Exercisable and Expiration Date (Month/Day/Year)		7. Title and Amount of Securities Underlying Derivative Security (Instr. 3 and 4)		8. Price of Derivative Security (Instr. 5)	9. Number of derivative Securities Beneficially Owned Following Reported Transaction(s) (Instr. 4)	10. Ownership Form: Direct (D) or Indirect (I) (Instr. 4)	11. Nature of Indirect Beneficial Ownership (Instr. 4)
				Code	V	(A)	(D)	Date Exercisable	Expiration Date	Title	Amount or Number of Shares

1. Name and Address of Reporting Person* SIMON NICHOLAS J III (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR (Street) BOSTON MA 02116 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* GALAKATOS NICHOLAS (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR (Street) BOSTON MA 02116 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* HENNER DENNIS (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR (Street) BOSTON MA 02116 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

1. Name and Address of Reporting Person* WHEELER KURT (Last) (First) (Middle) C/O MPM ASSET MANAGEMENT 200 CLARENDON ST., 54TH FLOOR (Street) BOSTON MA 02116 (City) (State) (Zip) Relationship of Reporting Person(s) to Issuer Director X 10% Owner Officer (give title below) Other (specify below)

Explanation of Responses:

1. Pro rata distribution of partnership interests.

2. These shares were distributed as follows: 39,814 shares by MPM BioVentures III, L.P., ("BV III"), 592,101 shares by MPM BioVentures III-QP, L.P. ("BV III QP"), 50,038 shares held by MPM BioVentures III GmbH & Co. Beteiligungs KG ("BV KG"), 17,883 shares by MPM BioVentures III Parallel Fund, L.P. ("BV III PF") and 14,076 shares held by MPM Asset Management Investors 2004 BVIII LLC ("AM BV III"). MPM BioVentures III GP, L.P. ("BV III GP") and MPM BioVentures III LLC ("BV III LLC") are the direct and indirect general partners of BV III, BV III QP, BV III PF and BV KG. Nicholas Galakatos, Dennis Henner, Nicholas Simon, III and Kurt Wheeler are members of BV III LLC and AM BV III. Each Reporting Person disclaims beneficial ownership of all such shares except to the extent of their respective proportionate pecuniary interests therein.

3. On October 18, 2007, additional shares were received pursuant to a declaration of a stock dividend as follows: 2,672 by BV III, 39,748 by BV III QP, 3,359 by BV KG, 1,200 by BV III PF and 944 by AM BV III.

4. The shares are held as follows: 70,369 by BV III, 1,046,493 by BV III QP, 88,437 by BV KG, 31,606 by BV III PF and 24,877 by AM BV III. Each Reporting Person disclaims beneficial ownership of all such shares except to the extent of their respective proportionate pecuniary interests therein.

5. The shares were sold as follows: 725 by BV III, 10,776 by BV III QP, 911 by BV KG, 325 by BV III PF and 256 by AM BV III.

6. The shares are held as follows: 69,644 by BV III, 1,035,717 by BV III QP, 87,526 by BV KG, 31,281 by BV III PF and 24,621 by AM BV III. Each Reporting Person disclaims beneficial ownership of all such shares except to the extent of their respective proportionate pecuniary interests therein.

7. The shares are held as follows: 10,632 by Nicholas Galakatos and 304 by AAG Peakham LLC, of which Mr. Galakatos is a member. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

8. The shares are held as follows: 4,645 by Dennis Henner and 745 by Henner Revocable Trust, of which Mr. Henner is a trustee. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

9. The shares are held as follows: 5,074 by Nicholas Simon, III and 43 by Simon Family Ventures, L.P., of which Mr. Simon is a general partner. The Reporting Person disclaims beneficial ownership of the securities except to the extent of his pecuniary interest therein.

10. The shares are held by Kurt Wheeler.

11. The shares are held by BV III GP. Each Reporting Person disclaims beneficial ownership of all such shares except to the extent of their respective proportionate pecuniary interests therein.

Remarks:

See Form 4 for MPM BioVentures III-QP, L.P. for additional members of this joint filing.

	/s/ Nicholas J. Simon, III	02/06/2008
	/s/ Nicholas Galakatos	02/06/2008
	/s/ Dennis Henner	02/06/2008
	/s/ Kurt Wheeler	02/06/2008
	** Signature of Reporting Person	Date
Reminder: Report on a separate line for each class of securities beneficially owned directly or indirectly.
* If the form is filed by more than one reporting person, see Instruction 4 (b)(v).
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