Business Segment, Geographic, and Concentration Risk Information - Summary of Revenue by Product Group (Detail) - USD ($) $ in Thousands	3 Months Ended								12 Months Ended
	Dec. 31, 2017	Sep. 30, 2017	Jun. 30, 2017	Mar. 31, 2017	Dec. 31, 2016	Sep. 30, 2016	Jun. 30, 2016	Mar. 31, 2016	Dec. 31, 2017	Dec. 31, 2016	Dec. 31, 2015
Total revenue by product group:
Total consolidated revenue	$ 14,873	$ 13,994	$ 4,595	$ 4,581	$ 5,113	$ 5,616	$ 5,193	$ 4,629	$ 38,043	$ 20,551	$ 13,944
API Sales
Total revenue by product group:
Total consolidated revenue									15,351	15,331	9,179
Medical Device Sales
Total revenue by product group:
Total consolidated revenue									1,747	2,338	1,966
Contract Manufacturing Revenue
Total revenue by product group:
Total consolidated revenue									1,360	1,497	1,464
Commercial Product Sales
Total revenue by product group:
Total consolidated revenue									17,648	228	224
License Fees and Consulting Revenue
Total revenue by product group:
Total consolidated revenue									1,105	392	297
Grant Revenue
Total revenue by product group:
Total consolidated revenue									$ 832	$ 765	$ 814