21.	commitments and contingencies

Rental and lease commitments

In August 2015, the Company entered into a lease agreement with FSMC to occupy a portion of the Conventus Center for Collaborative Medicine in Buffalo, NY. A deferred rent liability for this agreement of $1.5 million and $0.9 million was recorded as of December 31, 2017 and 2016, respectively. Total rent expense related to this location, recognized on a straight-line basis, for the years ended December 31, 2017, 2016, and 2015 were $1.0 million, $1.0 million, and $0.4 million, respectively,.

In July 2015, CDE entered into an agreement to lease facilities in Hong Kong. Under the rental agreement, CDE will make monthly payments of less than $0.1 million for three years beginning on July 1, 2015. Total rent expense related to this location, recognized on a straight-line basis, amounted to $0.4 million, $0.3 million, and $0.2 million for the years ended December 31, 2017, 2016, and 2015, respectively.

In October 2016, the Company’s Commercial Platform entered into an agreement to lease office space in Chicago, IL. Under the lease agreement, the Company will make monthly payments based on an escalating scale over ten years. Total rent expense related to this location, recognized on a straight-line basis, amounted to $0.2 million, less than $0.1 million, and $0 for the years ended December 31, 2017, 2016, and 2015, respectively. The Company has recorded a deferred rent liability of $0.3 million and less than $0.1 million as of December 31, 2017 and 2016, respectively. In lieu of a security deposit, an irrevocable letter of credit was issued to the landlord in the amount of $0.3 million.

The Company entered into a lease agreement expiring in 2025 to lease office space in Cranford, New Jersey that serves as its clinical research headquarters. Rent expense is recognized on a straight-line basis and amounted to $0.1 million for each of the years ended December 31, 2017, 2016, and 2015, respectively.

The Company entered into a lease agreement expiring in 2022 to lease office space in Taipei, Taiwan which serves for clinical research and clinical data management. Rent expense is recognized on a straight-line basis and amounted to less than $0.1 million for each of the years ended December 31, 2017, 2016, and 2015, respectively.

The Company leases its manufacturing and office facilities in Chongqing, China, where it produces API and performs research and development. Rent expense is recognized on a straight-line basis and amounted to $0.6 million, $0.6 million, and $0.3 million for the years ended December 31, 2017, 2016, and 2015, respectively.

Future minimum payments under the non-cancelable operating leases consists of the following as of December 31, 2017 (in thousands):

Year ending December 31:	Minimum payments
2018	$	2,138
2019		2,383
2020		2,247
2021		1,844
2022		1,802
Thereafter		4,672
	$	15,086

Legal Proceedings

The Company is not a party to any pending or known threatened legal proceedings that, in the opinion of the Company, would have a material impact on the Company’s consolidated financial statements.