X0306 4 2018-06-05 0 0001300699 Athenex, Inc. ATNX 0001708966 Trainor-Degirolamo Sheldon C/O ATHENEX, INC. 1001 MAIN STREET, SUITE 600 BUFFALO NY 14203 1 0 0 0 Common Stock 2018-06-05 4 S 0 57421 16.82 D 723734 I By PacBridge Partners V Investment Co Ltd. Stock Option (Right to Buy) 11.00 2027-06-14 Common Stock 19500 19500 D This transaction was executed in multiple trades ranging from $16.80 to $16.94. The price reported in Column 4 is a weighted average price. The reporting person hereby undertakes to provide upon request to the SEC staff, the Issuer or a security holder full information regarding the number of shares and prices at which the transactions were effected. These shares are held for the account of PacBridge Partners V Investment Co Ltd. Sheldon Trainor-Degirolamo ("Mr. Trainor-Degirolamo") is the sole director and shareholder of PacBridge Partners V Investment Co Ltd. and has sole voting and dispositive power over the shares held by it. Mr. Trainor-Degirolamo disclaims beneficial ownership of the reported securities except to the extent, if any, of its or his pecuniary interest therein, and this report shall not be deemed an admission that Mr. Trainor-Degirolamo is the beneficial owner of the reported securities for purposes of Section 16 of the Securities Exchange Act of 1934, as amended, or for any other purpose. The option vests in four equal annual installments beginning on June 14, 2018. /s/ Teresa Bair, Attorney-in-Fact 2018-06-06