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Debt and Lease Obligations - Additional Information (Detail)
1 Months Ended 6 Months Ended 12 Months Ended
Jun. 29, 2022
USD ($)
Jun. 21, 2022
USD ($)
Jan. 19, 2022
USD ($)
Tranche
$ / shares
Jan. 04, 2022
USD ($)
Oct. 01, 2021
USD ($)
ft²
Jan. 05, 2021
¥ / m²
Sep. 17, 2020
Jun. 19, 2020
USD ($)
Tranche
Jun. 30, 2022
Jun. 30, 2022
USD ($)
Dec. 31, 2022
USD ($)
Dec. 31, 2021
USD ($)
Mar. 20, 2023
USD ($)
Sep. 30, 2022
USD ($)
Jun. 14, 2022
USD ($)
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     $ 36,989,000 $ 45,938,000      
Royalty financing liability                     86,745,000        
Gain (Loss) on Extinguishment of Debt                     (3,134,000) (648,000)      
Revenue                     102,821,000 95,369,000      
Amortization of debt discount and royalty financing liability                     4,362,000 2,939,000      
Third Amendment to Credit Agreement                              
Debt Instrument [Line Items]                              
Mandatory prepayment of principal percentage     62.50%                        
Fee percentage     7.00%                        
Exit fee percentage     2.00%                        
Amendment fee     $ 300,000                        
Additional mandatory prepayment in principal       $ 12,500,000                      
Prepayment fee percentage     5.00%                        
Debt instrument payments                             $ 5,000,000.0
Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument payments                     7,500,000        
Fourth and Fifth Amendment to Credit Agreement                              
Debt Instrument [Line Items]                              
Liability recorded                     $ 45,700,000        
Fee percentage     5.00%                        
Exit fee percentage     2.00%                        
Prepayment fee percentage     3.00%                        
Additional prepayment in principal     $ 52,500,000                        
Debt incremental borrowing rate                     20.10%        
Gain (Loss) on Extinguishment of Debt                     $ 2,100,000        
Discount on extinguishment of debt                     $ 11,800,000        
Sixth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Fee percentage                     5.00%        
Exit fee percentage                     2.00%        
Prepayment fee percentage                     3.00%        
Debt instrument payments                     $ 6,800,000        
Third Fourth Fifth And Sixth Amendment To Credit Agreement Member                              
Debt Instrument [Line Items]                              
Debt instrument periodic payment                     121,300,000        
Third And SIxth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Gain (Loss) on Extinguishment of Debt                     (5,200,000)        
Chinese Subsidiaries | API Facility or Sintaho API Facility | Chongqing International Biological City Development & Investment Co., Ltd                              
Debt Instrument [Line Items]                              
Area of rent free lease | m²           34,517                  
Lease term           10 years                  
Renewal lease term           10 years                  
Payment of monthly rent per square meter | ¥ / m²           5                  
Revenue Interest Purchase Agreement                              
Debt Instrument [Line Items]                              
Royalty financing liability   $ 85,000,000.0                          
Escrow deposit $ 5,000,000.0 5,000,000.0                 3,500,000     $ 1,500,000  
Royalty financing liability transaction cost 5,000,000.0 5,000,000.0                 5,000,000.0        
Senior credit agreement payment   52,500,000                          
Deposit and held in segregated account $ 7,500,000 7,500,000                          
Deposits on escrow released   1,500,000                          
Royalty financing fund received                     $ 75,000,000.0        
Estimated cash flows year                     2035        
Royalty financing annual interest rate                     27.15%        
Revenue Interest Purchase Agreement | Sixth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Royalty financing fund received   $ 7,500,000                          
License Agreement With Almairall S.A. | SPV                              
Debt Instrument [Line Items]                              
Milestone interests percentage   50.00%                          
Milestone payments payable   $ 155,000,000.0                          
Royalties payment percentage   50.00%                          
License Agreement With Almairall S.A. | SPV | Sagard                              
Debt Instrument [Line Items]                              
Percentage of equity interests   10.00%                          
License Agreement With Almairall S.A. | SPV | Oaktree Fund Administration, Limited Liability Company [Member]                              
Debt Instrument [Line Items]                              
Percentage of equity interests   10.00%                          
License And Development Agreement With Almairall S.A.                              
Debt Instrument [Line Items]                              
Milestone interests percentage 50.00%                            
Milestone payments payable $ 155,000,000.0                            
Royalties payment percentage 50.00%                            
Royalty financing fund received                     $ 900,000        
Senior Credit Agreement                              
Debt Instrument [Line Items]                              
Debt maturity date                     Jun. 19, 2026        
Number of tranches | Tranche     2         5              
Debt instrument, maximum borrowing capacity               $ 225,000,000.0              
Available borrowing capacity upon approval of oral paclitaxel               $ 75,000,000.0              
Interest rate terms                     The loan bears interest at a fixed annual rate of 11.0%. The Company allocated the proceeds of the drawn tranches between liability and equity components and the fair value of such equity components, along with the direct costs related to the issuance of the debt were recorded as an offset to long-term debt on the consolidated balance sheets. The debt discount and financing fees are amortized on a straight-line basis, which approximates the effective interest method, over the remaining maturity of the Senior Credit Agreement. The effective interest rate of Tranches A, B and D, including the amortization of debt discount and financing fees amounts to 13.3% annually. The Company is required to make quarterly interest-only payments until June 19, 2022, after which the Company is required to make quarterly amortizing payments of $2.8 million, with the remaining balance of the principal plus accrued and unpaid interest due at maturity.        
Bearing interest at a fixed annual rate               11.00%              
Commitment fee percentage will be paid             0.60%                
Mandatory prepayment of principal percentage     62.50%                        
Fee percentage     7.00%           5.00%            
Exit fee percentage     2.00%           2.00%            
Amendment fee     $ 300,000                        
Additional mandatory prepayment in principal     $ 12,500,000                        
Prepayment fee percentage     5.00%           3.00%            
Exit fee liability                     $ 1,100,000        
Minimum liquidity amount in cash or permitted cash equivalent investments amount               $ 20,000,000.0              
Line of credit from first step up date until maturity               25,000,000.0              
Line of credit facility second step up date outstanding amount               225,000,000.0              
Line of credit from second step up date until maturity               $ 30,000,000.0              
Minimum revenue percentage               50              
Purchase price | $ / shares     $ 252.60                        
Line of credit due                     44,700,000 150,000,000.0      
Amortization of debt discount and royalty financing liability               $ 2,800,000              
Senior Credit Agreement | Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Minimum revenue percentage               70              
Senior Credit Agreement | Fifth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Revenue targets minimum liquidity amount decreased                   $ 10,000,000.0          
Senior Credit Agreement | Third Amendment on January 2022                              
Debt Instrument [Line Items]                              
Available borrowing capacity upon approval of oral paclitaxel     $ 0                        
Senior Credit Agreement | Oaktree Fund Administration, Limited Liability Company [Member] | Subsequent Event                              
Debt Instrument [Line Items]                              
Accounts payable owed to counterparties                         $ 10,000,000.0    
Senior Credit Agreement | Minimum                              
Debt Instrument [Line Items]                              
Line of credit facility first step up date outstanding amount               $ 150,000,000.0              
Senior Credit Agreement | Minimum | Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Covenant leverage ratio               4.50              
Senior Credit Agreement | Maximum                              
Debt Instrument [Line Items]                              
Covenant leverage ratio               4.50              
Lease Agreement | New York State | GMP Pharmaceutical Manufacturing Plant                              
Debt Instrument [Line Items]                              
Lease term         10 years                    
Renewal lease term         10 years                    
Area of building space built under agreement | ft²         409,000                    
Payment of annual rent         $ 2                    
Dunkirk Transaction                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     16,900,000        
Senior secured loan as long-term debt                     20,100,000        
Debt discount and financing fees                     7,700,000        
Dunkirk Transaction | Quarterly Payment Two                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     2,800,000        
Dunkirk Transaction | Quarterly Payment Three                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     2,800,000        
Dunkirk Transaction | Quarterly Payment Four                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     2,800,000        
Dunkirk Transaction | Expected To Be Due From Sale of Operations                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan, net of debt discount and financing fees of $7,698 and $0, respectively                     5,600,000        
Tranche A,B and D | Senior Credit Agreement                              
Debt Instrument [Line Items]                              
Amortization of debt discount financing fees percentage               13.30%              
Debt instrument, amount drawn                     150,000,000.0        
Tranche C and E | Senior Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument, amount drawn                     $ 75,000,000.0        
Senior Secured Loan                              
Debt Instrument [Line Items]                              
Senior secured loan as long-term debt                       $ 95,400,000