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Consolidated Statements of Cash Flows - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2022
Dec. 31, 2021
Cash flows from operating activities:    
Net loss from continuing operations $ (98,975) $ (160,354)
Net loss from discontinued operations (5,448) (41,682)
Adjustments to reconcile net loss to net cash used in operating activities of continuing operations:    
Depreciation and amortization 2,322 3,138
Stock-based compensation expense 6,326 9,207
Impairment of goodwill and intangible assets 79 41,011
Change in fair value of contingent consideration (4,190) 4,237
Provision for credit losses 134 (456)
Amortization of debt discount 4,362 2,939
Change in fair value of royalty financing liability 10,240  
Loss (gain) on disposal of assets 442 (331)
Loss on extinguishment of debt and write-off of deferred issuance costs 3,134 648
Deferred income taxes   (10,848)
Changes in operating assets and liabilities, net of effect of acquisition:    
Receivables, net (5,221) (2,752)
Prepaid expenses and other assets 656 3,272
Inventories (19,586) (122)
Accounts payable and accrued expenses 35,929 (19,385)
Net cash used in operating activities of continuing operations (64,348) (129,796)
Cash flows from investing activities of continuing operations:    
Purchase of property and equipment (417) (474)
Payments for licenses (1,643) (2,137)
Acquisition activity   1,425
Disposal activity   101
Purchases of short-term investments (9,087) (68,672)
Sale of short-term investments 18,683 197,608
Net cash provided by investing activities of continuing operations 7,536 127,851
Cash flows from financing activities of continuing operations:    
Proceeds from sale of stock 29,177 1,343
Proceeds from issuance of royalty financing liability 81,500  
Proceeds from issuance of warrants and pre-funded warrants 11,050  
Costs incurred related to the sale of stock (1,464)  
Costs incurred related to the issuance warrants and pre-funded warrants (684)  
Costs incurred related to the issuance of royalty financing liability (4,982)  
Costs incurred related to the prepayment of debt (6,515)  
Proceeds from exercise of stock options   1,579
Repurchase of treasury stock (272) (79)
Repayment of finance lease obligations and long-term debt and royalty financing liability (105,439) (106)
Net cash provided by financing activities of continuing operations 2,371 2,737
Net (decrease) increase in cash, cash equivalents, and restricted cash from continuing operations (54,441) 792
Net cash used in operating activities of discontinued operations (10,666) (12,585)
Net cash provided by (used in) investing activities of discontinued operations 50,366 (22,866)
Net cash used in financing activities of discontinued operations (807) (274)
Net increase (decrease) in cash and cash equivalents from discontinued operations 38,893 (35,725)
Cash, cash equivalents, and restricted cash beginning of period 51,702 86,087
Effect of exchange rate changes on cash, cash equivalents, and restricted cash (534) 548
Cash, cash equivalents, and restricted cash, end of period (See Note 5) 35,620 51,702
Supplemental cash flow disclosures    
Interest paid 11,088 20,336
Income taxes paid 586 108
Non-cash investing and financing activities:    
Accrued purchases of property and equipment from continuing operations 21 246
Accrued purchases of property and equipment from discontinued operations   1,679
Modification of warrants 283  
Accrued purchases of licenses 1,138 1,250
ROU assets recognized in exchange for new lease obligations 146 203
ROU assets derecognized from modification of operating lease obligations $ (128) (114)
Equity consideration in connection with acquisition   $ 52,786