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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
9 Months Ended
Sep. 30, 2022
Sep. 30, 2021
Cash flows from operating activities:    
Net loss from continuing operations $ (73,193) $ (87,945)
Net gain (loss) from discontinued operations 3,018 (9,009)
Adjustments to reconcile net loss to net cash used in operating activities of continuing operations:    
Depreciation and amortization 2,216 2,905
Stock-based compensation expense 4,886 7,328
Amortization of Debt Discount and Royalty Interest Financing 6,210 2,253
Change in fair value of contingent consideration (5,139) 3,647
Loss on disposal of assets and impairment charges 78 112
Loss on extinguishment of debt and write off of deferred issuance costs 1,450 648
Deferred income taxes   (10,781)
Changes in operating assets and liabilities:    
Receivables, net (6,626) (11,019)
Prepaid expenses and other assets 1,331 54
Inventories (14,990) (1,107)
Accounts payable and accrued expenses 31,235 (3,069)
Net cash used in operating activities of continuing operations (52,542) (96,974)
Cash flows from investing activities of continuing operations:    
Purchase of property and equipment (473) (819)
Payments for licenses (1,643) (1,588)
Cash acquired from Kuur acquisition   1,425
Purchases of short-term investments (9,087) (68,672)
Sales and maturities of short-term investments 18,633 192,393
Net cash provided by investing activities of continuing operations 7,430 122,739
Cash flows from financing activities of continuing operations:    
Proceeds from sale of stock 25,582 133
Proceeds from issuance of royalty financing liability 81,500  
Proceeds from issuance of warrants and pre-funded warrants 11,050  
Proceeds from exercise of stock options   1,579
Repurchase of treasury stock (272) (79)
Costs incurred related to the sale of stock (1,360)  
Costs incurred related to the issuance of warrants and pre-funded warrants (684)  
Costs incurred related to the issuance of royalty financing liability (4,982)  
Costs incurred related to the prepayment of debt (5,969)  
Repayment of finance lease obligations and long-term debt and royalty financing liability (102,613) (225)
Net cash provided by financing activities of continuing operations 2,252 1,408
Net (decrease) increase in cash, cash equivalents, and restricted cash from continuing operations (42,860) 27,173
Net cash used in operating activities of discontinued operations (8,078) (6,992)
Net cash provided by (used in) investing activities of discontinued operations 37,967 (16,377)
Net cash used in financing activities of discontinued operations (791) (56)
Net increase (decrease) in cash and cash equivalents from discontinued operations 29,098 (23,425)
Cash, cash equivalents, and restricted cash, beginning of period 51,702 86,087
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 2,472 259
Cash, cash equivalents, and restricted cash, end of period (See Note 5) 40,412 90,094
Supplemental cash flow disclosures    
Interest paid 9,767 11,878
Interest paid by discontinued operations 15 16
Non-cash investing and financing activities:    
Accrued purchases of property and equipment from continuing operations   28
Accrued purchases of property and equipment from discontinued operations 911 3,072
Accrued purchases of licenses 850 1,600
ROU assets derecognized from modification of operating lease obligations (128) (113)
ROU assets recognized in exchange for operating lease obligations $ 78 $ 86