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Condensed Consolidated Statements of Cash Flows (unaudited) - USD ($)
$ in Thousands
6 Months Ended
Jun. 30, 2022
Jun. 30, 2021
Cash flows from operating activities:    
Net loss from continuing operations $ (53,269) $ (53,134)
Net gain (loss) from discontinued operations 2,963 (7,084)
Adjustments to reconcile net loss to net cash used in operating activities of continuing operations:    
Depreciation and amortization 1,470 1,986
Stock-based compensation expense 3,477 4,678
Amortization of debt discount 1,029 1,533
Change in fair value of contingent consideration 53 398
Loss on disposal of assets and impairment charges 78  
Loss on extinguishment of debt and write off of deferred issuance costs 1,450 648
Deferred income taxes   (10,940)
Changes in operating assets and liabilities:    
Receivables, net (7,538) 520
Prepaid expenses and other assets 1,443 (261)
Inventories (10,802) (613)
Accounts payable and accrued expenses 25,798 (8,579)
Net cash used in operating activities of continuing operations (36,811) (63,764)
Cash flows from investing activities of continuing operations:    
Purchase of property and equipment (360) (491)
Payments for licenses (668) (1,588)
Cash acquired from Kuur acquisition   1,425
Purchases of short-term investments (9,488) (67,600)
Sales and maturities of short-term investments 18,976 152,950
Net cash provided by investing activities of continuing operations 8,460 84,696
Cash flows from financing activities of continuing operations:    
Proceeds from sale of stock 4,663 133
Proceeds from issuance of royalty financing liability 80,000  
Proceeds from exercise of stock options   1,579
Repurchase of treasury stock   (79)
Costs incurred related to the issuance of royalty financing liability (4,982)  
Costs incurred related to the prepayment of debt (5,625)  
Repayment of finance lease obligations and long-term debt and royalty financing liability (92,584) (99)
Net cash (used in) provided by financing activities of continuing operations (18,528) 1,534
Net (decrease) increase in cash, cash equivalents, and restricted cash from continuing operations (46,879) 22,466
Net cash used in operating activities of discontinued operations (7,535) (5,326)
Net cash provided by (used in) investing activities of discontinued operations 37,747 (9,968)
Net cash used in financing activities of discontinued operations (792) (85)
Net increase (decrease) in cash and cash equivalents from discontinued operations 29,420 (15,379)
Cash, cash equivalents, and restricted cash, beginning of period 51,702 86,087
Effect of exchange rate changes on cash, cash equivalents, and restricted cash 1,721 267
Cash, cash equivalents, and restricted cash, end of period (See Note 5) 35,964 93,441
Supplemental cash flow disclosures    
Interest paid 7,702 7,708
Interest paid by discontinued operations 15 7
Non-cash investing and financing activities:    
Accrued purchases of property and equipment from continuing operations 17 123
Accrued purchases of property and equipment from discontinued operations 1,213 2,585
Accrued purchases of licenses 1,925 $ 1,600
ROU assets derecognized from modification of operating lease obligations (128)  
ROU assets recognized in exchange for operating lease obligations $ 78