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Related Party Transactions - Additional Information (Detail)
1 Months Ended 3 Months Ended 6 Months Ended 12 Months Ended
Jul. 31, 2021
USD ($)
Jun. 30, 2019
Jun. 30, 2018
Agreement
Dec. 31, 2020
USD ($)
Jun. 30, 2022
USD ($)
shares
Jun. 30, 2021
USD ($)
Dec. 31, 2021
USD ($)
shares
Related Party Transaction [Line Items]              
Deferred revenue         $ 2,781,000   $ 2,799,000
Pharma Essentia              
Related Party Transaction [Line Items]              
Milestone fee earned         0 $ 500,000  
Funds paid to related party         0 0  
Pharma Essentia | Maximum              
Related Party Transaction [Line Items]              
Licenses revenue         100,000    
Licenses revenue         $ 100,000    
Nuwagen Limited              
Related Party Transaction [Line Items]              
Percentage of ownership interest of newly formed entity   10.00%          
Avalon BioMedical              
Related Party Transaction [Line Items]              
Common stock shares held by related parties | shares         786,061   786,061
Avalon BioMedical | Maximum              
Related Party Transaction [Line Items]              
Percentage of common stock issued shares         1.00%   1.00%
Avalon BioMedical | Nuwagen Limited              
Related Party Transaction [Line Items]              
Percentage of ownership interest   90.00%          
Avalon BioMedical | In-licensing Agreement              
Related Party Transaction [Line Items]              
Number of in-licensing agreements | Agreement     2        
Milestone fee paid         $ 0 $ 0  
Milestone payment $ 2,000,000.0            
Axis Therapeutics Limited              
Related Party Transaction [Line Items]              
Licenses revenue       $ 1,000,000.0 1,000,000.0    
Licenses revenue       1,000,000.0 1,000,000.0    
License fee received withholding tax       $ 300,000 300,000    
Deferred revenue         $ 2,000,000.0