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Debt and Lease Obligations - Additional Information (Detail)
¥ in Millions
1 Months Ended 3 Months Ended 6 Months Ended
Jun. 21, 2022
USD ($)
Jan. 19, 2022
USD ($)
Tranche
Jan. 04, 2022
USD ($)
May 28, 2021
CNY (¥)
Jan. 05, 2021
¥ / m²
Sep. 17, 2020
Jun. 19, 2020
USD ($)
Tranche
May 15, 2020
CNY (¥)
Jun. 30, 2022
USD ($)
Jun. 30, 2022
USD ($)
Jun. 30, 2019
CNY (¥)
Jun. 30, 2022
USD ($)
Qtr
Jun. 30, 2021
USD ($)
Jun. 14, 2022
USD ($)
Dec. 31, 2021
USD ($)
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 $ 23,600,000 $ 23,600,000   $ 23,600,000     $ 45,938,000
Royalty financing liability                 75,006,000 75,006,000   75,006,000      
Gain on extinguishment of debt                   2,051,000   (1,450,000) $ (648,000)    
Third Amendment to Credit Agreement                              
Debt Instrument [Line Items]                              
Mandatory prepayment of principal percentage   62.50%                          
Fee percentage   7.00%                          
Exit fee percentage   2.00%                          
Prepayment fee percentage   5.00%                          
Amendment fee   $ 300,000                          
Additional mandatory prepayment in principal     $ 12,500,000                        
Debt instrument payments                           $ 5,000,000.0  
Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Additional prepayment in principal   $ 42,500,000                          
Debt instrument payments                 7,500,000 7,500,000   $ 7,500,000      
Fourth and Fifth Amendment to Credit Agreement                              
Debt Instrument [Line Items]                              
Fee percentage   5.00%                          
Exit fee percentage   2.00%                          
Prepayment fee percentage   3.00%                          
Debt incremental borrowing rate                       20.57%      
Discount on extinguishment of debt                 11,800,000 11,800,000   $ 11,800,000      
Liability recorded                 45,700,000 45,700,000   45,700,000      
Gain on extinguishment of debt                       2,100,000      
Third, Fourth and Fifth Amendment to Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument periodic payment                       97,600,000      
Chinese Subsidiaries | API Facility or Sintaho API Facility | Chongqing International Biological City Development & Investment Co., Ltd                              
Debt Instrument [Line Items]                              
Area of rent free lease | m²         34,517                    
Lease term         10 years                    
Renewal lease term         10 years                    
Payment of monthly rent per square meter | ¥ / m²         5                    
Revenue Interest Purchase Agreement                              
Debt Instrument [Line Items]                              
Royalty financing liability $ 85,000,000.0                            
Escrow deposit 5,000,000.0               5,000,000.0 5,000,000.0   5,000,000.0      
Royalty financing liability transaction cost 5,000,000.0                     5,000,000.0      
Senior credit agreement payment 52,500,000                            
Deposit and held in segregated account 7,500,000                            
Royalty financing fund received                       $ 75,000,000.0      
Royalty financing annual interest rate                       28.60%      
Estimated cash flows year                       2035      
License And Development Agreement With Almairall S.A.                              
Debt Instrument [Line Items]                              
Royalty financing fund received                       $ 500,000      
License Agreement With Almairall S.A. | ATNX SPV, LLC                              
Debt Instrument [Line Items]                              
Milestone payments payable $ 155,000,000.0                            
Milestone interests percentage 50.00%                            
Royalties payment percentage 50.00%                            
Oaktree | License Agreement With Almairall S.A. | ATNX SPV, LLC                              
Debt Instrument [Line Items]                              
Percentage of equity interests 10.00%                            
Sagard | License Agreement With Almairall S.A. | ATNX SPV, LLC                              
Debt Instrument [Line Items]                              
Percentage of equity interests 10.00%                            
Senior Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument, maximum borrowing capacity             $ 225,000,000.0                
Line of credit due                 57,500,000 57,500,000   $ 57,500,000     $ 150,000,000.0
Number of tranches | Tranche   2         5                
Debt maturity date                       Jun. 19, 2026      
Available borrowing capacity upon approval of oral paclitaxel             $ 75,000,000.0                
Interest rate terms                       The loan bears interest at a fixed annual rate of 11.0%. The Company allocated the proceeds of the drawn tranches between liability and equity components and the fair value of such equity components, along with the direct costs related to the issuance of the debt were recorded as an offset to long-term debt on the consolidated balance sheets. The debt discount and financing fees are amortized on a straight-line basis, which approximates the effective interest method, over the remaining maturity of the Senior Credit Agreement. The effective interest rate of Tranches A, B and D, including the amortization of debt discount and financing fees amounts to 13.3% annually. The Company is required to make quarterly interest-only payments until June 19, 2022, after which the Company is required to make quarterly amortizing payments, with the remaining balance of the principal plus accrued and unpaid interest due at maturity.      
Bearing interest at a fixed annual rate             11.00%                
Commitment fee percentage will be paid           0.60%                  
Exit fee liability                 $ 1,200,000 1,200,000   $ 1,200,000      
Mandatory prepayment of principal percentage   62.50%                          
Fee percentage   7.00%             5.00%            
Exit fee percentage   2.00%             2.00%            
Prepayment fee percentage   5.00%             3.00%            
Amendment fee   $ 300,000                          
Additional mandatory prepayment in principal   12,500,000                          
Minimum liquidity amount in cash or permitted cash equivalent investments amount             $ 20,000,000.0                
Line of credit from first step up date until maturity             25,000,000.0                
Line of credit facility second step up date outstanding amount             225,000,000.0                
Line of credit from second step up date until maturity             $ 30,000,000.0                
Minimum revenue percentage             50                
Gain on extinguishment of debt                       (3,500,000)      
Senior Credit Agreement | Third Amendment on January 2022                              
Debt Instrument [Line Items]                              
Available borrowing capacity upon approval of oral paclitaxel   $ 0                          
Senior Credit Agreement | Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Minimum revenue percentage             70                
Senior Credit Agreement | Fifth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Revenue targets minimum liquidity amount decreased                       10,000,000.0      
Senior Credit Agreement | Minimum                              
Debt Instrument [Line Items]                              
Line of credit facility first step up date outstanding amount             $ 150,000,000.0                
Senior Credit Agreement | Minimum | Fourth Amendment To Credit Agreement                              
Debt Instrument [Line Items]                              
Covenant leverage ratio             4.50                
Senior Credit Agreement | Maximum                              
Debt Instrument [Line Items]                              
Covenant leverage ratio             4.50                
Senior Credit Agreement | Tranche A,B and D                              
Debt Instrument [Line Items]                              
Debt instrument, amount drawn                 $ 150,000,000.0 150,000,000.0   150,000,000.0      
Amortization of debt discount financing fees percentage             13.30%                
Senior Credit Agreement | Tranche C and E                              
Debt Instrument [Line Items]                              
Debt instrument, amount drawn                 75,000,000.0 75,000,000.0   75,000,000.0      
Senior Credit Agreement | Tranche C 90 Days After Closing Date Through June 20, 2022                              
Debt Instrument [Line Items]                              
Debt instrument, amount drawn             $ 25,000,000.0                
Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument, maximum borrowing capacity                 800,000 800,000   800,000      
Debt maturity date       May 28, 2022                      
Credit agreement repaid date               May 14, 2021              
Dunkirk Transaction                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 23,600,000 23,600,000   $ 23,600,000      
Number Of quarterly payments | Qtr                       1      
Senior secured loan as long-term debt                 22,100,000 22,100,000   $ 22,100,000      
Debt discount and financing fees                 11,800,000 11,800,000   11,800,000      
Dunkirk Transaction | Quarterly Payment One                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 3,100,000 3,100,000   3,100,000      
Dunkirk Transaction | Quarterly Payment Two                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 2,800,000 2,800,000   2,800,000      
Dunkirk Transaction | Quarterly Payment Three                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 2,800,000 2,800,000   2,800,000      
Dunkirk Transaction | Quarterly Payment Four                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 2,800,000 2,800,000   2,800,000      
Dunkirk Transaction | Expected To Be Due From Sale of Operations                              
Debt Instrument [Line Items]                              
Current portion of senior secured loan                 12,000,000.0 12,000,000.0   $ 12,000,000.0      
Chongqing Maliu Riverside Development and Investment Co., LTD ("CQ")                              
Debt Instrument [Line Items]                              
Line of credit facility percentage of periodic payment year one                     20.00%        
Line of credit facility percentage of periodic payment year two                     30.00%        
Line of credit frequency of payments                       The Company is required to repay the principal amount with accrued interest within three years after the plant receives the cGMP certification, with 20% of the total loan with accrued interest due within the first twelve months following receiving the certification, 30% of the total loan with accrued interest due within twenty-four months, and the remaining balance with accrued interest due within thirty-six months.      
Line of credit due                 7,500,000 7,500,000   $ 7,500,000      
China | Credit Agreement                              
Debt Instrument [Line Items]                              
Debt instrument, maximum borrowing capacity | ¥       ¥ 5.0       ¥ 5.0              
China | Chongqing Maliu Riverside Development and Investment Co., LTD ("CQ")                              
Debt Instrument [Line Items]                              
Debt instrument, maximum borrowing capacity                 $ 7,500,000 $ 7,500,000 ¥ 50.0 $ 7,500,000      
Long-term line of credit, interest rate                     4.75%