Company and Nature of Business - Additional Information (Detail)				1 Months Ended	3 Months Ended		6 Months Ended		12 Months Ended
	Jun. 29, 2022 USD ($)	Jan. 19, 2022 USD ($) Tranche $ / shares	Jun. 19, 2020 USD ($) Tranche $ / shares shares	Jun. 30, 2022 USD ($) $ / shares	Jun. 30, 2022 USD ($) $ / shares	Jun. 30, 2021 shares	Jun. 30, 2022 USD ($) Segment $ / shares shares	Jun. 30, 2021 USD ($)	Dec. 31, 2021 USD ($) $ / shares shares	Jun. 21, 2022 USD ($)	Aug. 20, 2021 USD ($) $ / shares
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Number of operating segments | Segment							3
Accumulated deficit				$ 962,989,000	$ 962,989,000		$ 962,989,000		$ 913,412,000
Cash and cash equivalents				22,139,000	22,139,000		22,139,000		35,202,000
Restricted cash				13,800,000	13,800,000		13,800,000
Short-term investments				1,189,000	1,189,000		$ 1,189,000		10,207,000
Substantial doubt about going concern, conditions or events							The Company projects insufficient liquidity to fund its operations through the next twelve months beyond the date of the issuance of these condensed consolidated financial statements. This condition raises substantial doubt about the Company’s ability to continue as a going concern. Additionally, the Company has financial covenants associated with its Senior Credit Agreement with Oaktree that are measured each quarter. The Company is in compliance with such financial covenants as of June 30, 2022. However, the Company is forecasting that it will be in violation of the minimum liquidity covenant included within the Senior Credit Agreement during the twelve month period subsequent to the date of this filing. Pursuant to ASC 205-40-50, the Company’s forecast does not reflect management’s plans that are outside of the Company’s control as described below. Violation of any covenant under the Credit Agreement provides the lenders with the option to accelerate the maturity of the Credit Facility, which carried an outstanding principal balance of $57.5 million as of June 30, 2022. Should the lenders accelerate the maturity of the Credit Facility, the Company would not have sufficient cash on hand or available liquidity to repay the outstanding debt in the event of default. These conditions and events raise substantial doubt about the Company’s ability to continue as a going concern.
Substantial doubt about going concern, within next twelve months							true
Royalty financing liability				75,006,000	75,006,000		$ 75,006,000
Common stock value				$ 119,000	$ 119,000		$ 119,000		$ 111,000
Common stock, par value (in dollars per share) | $ / shares				$ 0.001	$ 0.001		$ 0.001		$ 0.001
Loss on extinguishment of debt					$ (2,051,000)		$ 1,450,000	$ 648,000
Revenue Interest Purchase Agreement
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Royalty financing liability										$ 85,000,000.0
Escrow deposit	$ 5,000,000.0
Royalty financing liability transaction cost	5,000,000.0
Senior credit agreement payment	56,600,000
Deposit and held in segregated account	7,500,000
Royalty and milestone interests remaining proceeds	$ 10,900,000
License And Development Agreement With Almairall S.A.
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Percentage of ownership interest	10.00%
Milestone interests percentage	50.00%
Milestone payments payable	$ 155,000,000.0
Royalties payment percentage	50.00%
Common Stock
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Number of shares issued and sold | shares						33,373
Senior Credit Agreement
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Line of credit due				$ 57,500,000	57,500,000		$ 57,500,000		$ 150,000,000.0
Debt instrument, maximum borrowing capacity			$ 225,000,000.0
Number of tranches | Tranche		2	5
Senior Credit Agreement, maturity date							Jun. 19, 2026
Bearing interest at a fixed annual rate			11.00%
Loss on extinguishment of debt							$ 3,500,000
Additional debt amount tranches available			$ 75,000,000.0
Purchase price | $ / shares		$ 12.63
Amended the warrants held issued, start date		Jun. 19, 2020
Amended the warrants held issued, end date		Aug. 04, 2020
Mandatory prepayment of principal percentage		62.50%
Fee percentage		7.00%		5.00%
Exit fee percentage		2.00%		2.00%
Prepayment fee percentage		5.00%		3.00%
Amendment fee		$ 300,000
Additional mandatory prepayment in principal		$ 12,500,000
Number of last tranches | Tranche		2	5
Percentage of warrant exercise price underlying lower		50.00%
Proceeds from credit agreement							40,000,000.0
Repay to credit agreement							27,400,000
Senior Credit Agreement | Amendment Provides Exercise Price for 50% of Shares Underlying
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Purchase price | $ / shares		$ 1.10
Senior Credit Agreement | Common Stock
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Purchase price | $ / shares			$ 12.63
Senior Credit Agreement | Common Stock | Maximum
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Warrant to purchase common stock | shares			908,393
Senior Credit Agreement | Tranche A
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Debt instrument, amount drawn			$ 100,000,000.0
Senior Credit Agreement | Tranche B
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Debt instrument, amount drawn			25,000,000.0
Senior Credit Agreement | Tranche C
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Debt instrument, amount drawn			$ 25,000,000.0
Senior Credit Agreement Third Amendment
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Repay to credit agreement				$ 13,700,000
Senior Credit Agreement Third Amendment | Amendment Provides Exercise Price for 50% of Shares Underlying
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Purchase price | $ / shares		1.10
Senior Credit Agreement Fourth Amendment
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Purchase price | $ / shares		$ 0.50
Senior Credit Agreement Fourth Amendment | Oaktree
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Line of credit due				7,500,000	$ 7,500,000		$ 7,500,000
Senior Credit Agreement Fifth Amendment
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Additional prepayment in principal				$ 10,000,000.0
ATM Shares | Sales Agreement | SVB Securities LLC
Organization Consolidation And Presentation Of Financial Statements [Line Items]
Common stock value											$ 100,000,000
Common stock, par value (in dollars per share) | $ / shares											$ 0.001
Number of shares issued and sold | shares							7,147,892		762,825
Common stock share price | $ / shares				$ 0.63	$ 0.63		$ 0.63		$ 1.49