Common stock shares held by related parties.

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License fee received, withholding tax.

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Milestone fee earned.

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Milestone fee paid.

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Milestone payment.

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Number of In-licensing agreements.

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- Definition

Percentage of common stock issued shares.

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- Definition

Amount of obligation to transfer good or service to customer for which consideration has been received or is receivable, classified as current.

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The percentage of ownership of common stock or equity participation in the investee accounted for under the equity method of accounting.

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Percentage investment held by members or limited partners of limited liability company (LLC) or limited partnership (LP).

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

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Purchases during the period (excluding transactions that are eliminated in consolidated or combined financial statements) with related party.

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Amount of revenue, fees and commissions earned from transactions between (a) a parent company and its subsidiaries; (b) subsidiaries of a common parent; (c) an entity and trusts for the benefit of employees, for example, but not limited to, pension and profit-sharing trusts that are managed by or under the trusteeship of the entity's management; (d) an entity and its principal, owners, management, or members of their immediate families; and (e) affiliates.

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Related Party Transactions - Additional Information (Detail)	1 Months Ended			3 Months Ended			12 Months Ended
	Jul. 31, 2021 USD ($)	Jun. 30, 2019	Jun. 30, 2018 Agreement	Mar. 31, 2022 USD ($) shares	Mar. 31, 2021 USD ($)	Dec. 31, 2020 USD ($)	Dec. 31, 2021 USD ($) shares
Related Party Transaction [Line Items]
Deferred revenue				$ 3,280,000			$ 3,291,000
Pharma Essentia
Related Party Transaction [Line Items]
Milestone fee earned				0	$ 500,000
Funds paid to related party				$ 0	0
Nuwagen Limited
Related Party Transaction [Line Items]
Percentage of ownership interest of newly formed entity		10.00%
Avalon BioMedical
Related Party Transaction [Line Items]
Common stock shares held by related parties \| shares				786,061			786,061
Avalon BioMedical \| Maximum
Related Party Transaction [Line Items]
Percentage of common stock issued shares				1.00%			1.00%
Avalon BioMedical \| Nuwagen Limited
Related Party Transaction [Line Items]
Percentage of ownership interest		90.00%
Avalon BioMedical \| In-licensing Agreement
Related Party Transaction [Line Items]
Number of in-licensing agreements \| Agreement			2
Milestone fee paid				$ 0	$ 0
Milestone payment	$ 2,000,000.0
Axis Therapeutics Limited
Related Party Transaction [Line Items]
Licenses revenue				1,000,000.0		$ 1,000,000.0
License fee received withholding tax				300,000		$ 300,000
Deferred revenue				$ 2,000,000.0