0001104659-23-018131.txt : 20230210
0001104659-23-018131.hdr.sgml : 20230210
20230210110249
ACCESSION NUMBER: 0001104659-23-018131
CONFORMED SUBMISSION TYPE: 13F-HR
PUBLIC DOCUMENT COUNT: 2
CONFORMED PERIOD OF REPORT: 20221231
FILED AS OF DATE: 20230210
DATE AS OF CHANGE: 20230210
EFFECTIVENESS DATE: 20230210
FILER:
COMPANY DATA:
COMPANY CONFORMED NAME: Tekla Capital Management LLC
CENTRAL INDEX KEY: 0001300336
IRS NUMBER: 010628853
STATE OF INCORPORATION: DE
FISCAL YEAR END: 0930
FILING VALUES:
FORM TYPE: 13F-HR
SEC ACT: 1934 Act
SEC FILE NUMBER: 028-10950
FILM NUMBER: 23609386
BUSINESS ADDRESS:
STREET 1: 100 FEDERAL STREET
STREET 2: 19TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02110
BUSINESS PHONE: 617 772-8500
MAIL ADDRESS:
STREET 1: 100 FEDERAL STREET
STREET 2: 19TH FLOOR
CITY: BOSTON
STATE: MA
ZIP: 02110
FORMER COMPANY:
FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC
DATE OF NAME CHANGE: 20040811
13F-HR
1
primary_doc.xml
X0202
13F-HR
LIVE
false
false
false
0001300336
XXXXXXXX
12-31-2022
12-31-2022
false
Tekla Capital Management LLC
100 Federal Street
19th Floor
Boston
MA
02110
13F HOLDINGS REPORT
028-10950
000119626
801-61018
N
Laura Woodward
Chief Compliance Officer
617-772-8500
/s/ Laura Woodward
Boston
MA
02-10-2023
0
172
2647841985
INFORMATION TABLE
2
infotable.xml
1Life Healthcare, Inc.
Common
68269G107
522455
31266
SH
SOLE
522455
0
0
Abbott Laboratories
Common
002824100
76090069
693051
SH
SOLE
76090069
0
0
AbbVie Inc.
Common
00287Y109
77304851
478342
SH
SOLE
77304851
0
0
Acadia Healthcare Company, Inc.
Common
00404A109
11622678
141189
SH
SOLE
11622678
0
0
ACADIA Pharmaceuticals Inc.
Common
004225108
1149822
72225
SH
SOLE
1149822
0
0
Adaptive Biotechnologies Corp.
Common
00650F109
3226227
422281
SH
SOLE
3226227
0
0
Addus HomeCare Corp.
Common
006739106
4216386
42380
SH
SOLE
4216386
0
0
Adicet Bio, Inc.
Common
007002108
360541
40329
SH
SOLE
360541
0
0
Affimed N.V.
Common
N01045108
726687
586038
SH
SOLE
726687
0
0
Agilent Technologies, Inc.
Common
00846U101
6463533
43191
SH
SOLE
6463533
0
0
AlerisLife Inc.
Common
33832D205
13330
24237
SH
SOLE
13330
0
0
Align Technology, Inc.
Common
016255101
10718782
50824
SH
SOLE
10718782
0
0
Alkermes plc
Shares
G01767105
8090188
309613
SH
SOLE
8090188
0
0
Allscripts Healthcare Solutions, Inc.
Common
01988P108
7560151
428580
SH
SOLE
7560151
0
0
Alnylam Pharmaceuticals, Inc.
Common
02043Q107
34034807
143214
SH
SOLE
34034807
0
0
ALX Oncology Holdings Inc.
Common
00166B105
746198
66211
SH
SOLE
746198
0
0
Amerisourcebergen Corp.
Common
03073E105
3383301
20417
SH
SOLE
3383301
0
0
Amgen Inc.
Common
031162100
133598665
508676
SH
SOLE
133598665
0
0
Apellis Pharmaceuticals, Inc.
Common
03753U106
3434888
66426
SH
SOLE
3434888
0
0
ARCA biopharma, Inc.
Common
00211Y506
76608
32461
SH
SOLE
76608
0
0
Arcutis Biotherapeutics, Inc.
Common
03969K108
2203335
148874
SH
SOLE
2203335
0
0
Ardelyx, Inc.
Common
039697107
1537313
539408
SH
SOLE
1537313
0
0
argenx SE
Sponsored ADR
04016X101
31829675
84021
SH
SOLE
31829675
0
0
Arrowhead Pharmaceuticals, Inc.
Common
04280A100
4073116
100422
SH
SOLE
4073116
0
0
Arvinas, Inc.
Common
04335A105
1470962
42998
SH
SOLE
1470962
0
0
Ascendis Pharma A/S
Sponsored ADR
04351P101
15118595
123791
SH
SOLE
15118595
0
0
Assertio Holdings, Inc.
Common
04546C205
1765473
410575
SH
SOLE
1765473
0
0
AstraZeneca PLC
Sponsored ADR
046353108
69308889
1022255
SH
SOLE
69308889
0
0
Avantor, Inc.
Common
05352A100
9690602
459488
SH
SOLE
9690602
0
0
Beam Therapeutics Inc.
Common
07373V105
618603
15817
SH
SOLE
618603
0
0
BeiGene, Ltd.
Sponsored ADR
07725L102
4608183
20952
SH
SOLE
4608183
0
0
Bellicum Pharmaceuticals, Inc.
Common
079481404
4320
6000
SH
SOLE
4320
0
0
Bicycle Therapeutics PLC
Sponsored ADS
088786108
2624810
88676
SH
SOLE
2624810
0
0
BioCryst Pharmaceuticals, Inc.
Common
09058V103
7722653
672705
SH
SOLE
7722653
0
0
Biogen Inc.
Common
09062X103
54118476
195430
SH
SOLE
54118476
0
0
Biohaven Ltd.
Common
G1110E107
487008
35087
SH
SOLE
487008
0
0
BioMarin Pharmaceutical Inc.
Common
09061G101
23884457
230790
SH
SOLE
23884457
0
0
BioNTech SE
Sponsored ADS
09075V102
15601549
103858
SH
SOLE
15601549
0
0
Black Diamond Therapeutics, Inc.
Common
09203E105
237582
131990
SH
SOLE
237582
0
0
Blueprint Medicines Corp.
Common
09627Y109
2966375
67710
SH
SOLE
2966375
0
0
Boston Scientific Corp.
Common
101137107
35027084
757015
SH
SOLE
35027084
0
0
Bristol-Myers Squibb Company
Common
110122108
49467712
687529
SH
SOLE
49467712
0
0
Cardiovascular Systems, Inc.
Common
141619106
2381580
174859
SH
SOLE
2381580
0
0
Caribou Biosciences, Inc.
Common
142038108
3561683
567147
SH
SOLE
3561683
0
0
Catalent, Inc.
Common
148806102
5668874
125947
SH
SOLE
5668874
0
0
Cerevel Therapeutics Holdings, Inc.
Common
15678U128
5566274
176483
SH
SOLE
5566274
0
0
Charles River Laboratories International, Inc.
Common
159864107
15835883
72675
SH
SOLE
15835883
0
0
Cigna Corp.
Common
125523100
60512956
182631
SH
SOLE
60512956
0
0
Codexis Inc
Common
192005106
322123
69125
SH
SOLE
322123
0
0
Community Health Systems, Inc.
Common
203668108
381607
88335
SH
SOLE
381607
0
0
Community Healthcare Trust Inc.
Common
20369C106
533420
14900
SH
SOLE
533420
0
0
Corbus Pharmaceuticals Holdings, Inc.
Common
21833P103
17051
154310
SH
SOLE
17051
0
0
Crinetics Pharmaceuticals, Inc.
Common
22663K107
839256
45861
SH
SOLE
839256
0
0
CRISPR Therapeutics AG
Namen AKT
H17182108
2239002
55080
SH
SOLE
2239002
0
0
CVS Health Corp.
Common
126650100
8724541
93621
SH
SOLE
8724541
0
0
Cytokinetics, Inc.
Common
23282W605
3442869
75139
SH
SOLE
3442869
0
0
Danaher Corp.
Common
235851102
28052240
105690
SH
SOLE
28052240
0
0
Denali Therapeutics, Inc.
Common
24823R105
7578781
272520
SH
SOLE
7578781
0
0
Dexcom, Inc.
Common
252131107
24688019
218015
SH
SOLE
24688019
0
0
Diversified Healthcare Trust
Common
25525P107
231373
357720
SH
SOLE
231373
0
0
Edgewise Therapeutics, Inc.
Common
28036F105
1743524
195025
SH
SOLE
1743524
0
0
Edwards Lifesciences Corp.
Common
28176E108
12787259
171388
SH
SOLE
12787259
0
0
Elevance Health, Inc.
Common
036752103
7511933
14644
SH
SOLE
7511933
0
0
Eli Lilly and Company
Common
532457108
105697395
288917
SH
SOLE
105697395
0
0
Fulcrum Therapeutics, Inc.
Common
359616109
426149
58537
SH
SOLE
426149
0
0
Fusion Pharmaceuticals Inc.
Common
36118A100
136691
43394
SH
SOLE
136691
0
0
G1 Therapeutics, Inc.
Common
3621LQ109
2301609
423869
SH
SOLE
2301609
0
0
Galera Therapeutics, Inc.
Common
36338D108
1338577
898374
SH
SOLE
1338577
0
0
Gilead Sciences, Inc.
Common
375558103
129671274
1510440
SH
SOLE
129671274
0
0
Global Medical REIT Inc.
Common
37954A204
1658024
174897
SH
SOLE
1658024
0
0
GSK plc ADR
Sponsored ADR
37733W204
1470679
41852
SH
SOLE
1470679
0
0
Guardant Health, Inc.
Common
40131M109
12843405
472184
SH
SOLE
12843405
0
0
Harpoon Therapeutics, Inc.
Common
41358P106
188617
259910
SH
SOLE
188617
0
0
HCA Healthcare, Inc.
Common
40412C101
25196520
105003
SH
SOLE
25196520
0
0
Healthcare Realty Trust Inc.
Common
42226K105
3366199
174686
SH
SOLE
3366199
0
0
HealthEquity, Inc.
Common
42226A107
6793591
110214
SH
SOLE
6793591
0
0
Healthpeak Properties, Inc.
Common
42250P103
3770327
150392
SH
SOLE
3770327
0
0
Horizon Therapeutics plc
Common
G46188101
47233031
415053
SH
SOLE
47233031
0
0
Humana Inc.
Common
444859102
39803821
77713
SH
SOLE
39803821
0
0
I-Mab
Sponsored ADS
44975P103
679584
162580
SH
SOLE
679584
0
0
Icon plc
Shares
G4705A100
1813130
9334
SH
SOLE
1813130
0
0
IDEAYA Biosciences, Inc.
Common
45166A102
2419971
133185
SH
SOLE
2419971
0
0
IDEXX Laboratories, Inc.
Common
45168D104
27767797
68065
SH
SOLE
27767797
0
0
Illumina, Inc.
Common
452327109
64695508
319958
SH
SOLE
64695508
0
0
Intellia Therapeutics, Inc.
Common
45826J105
5382445
154269
SH
SOLE
5382445
0
0
Intercept Pharmaceuticals, Inc.
Common
45845P108
644069
52067
SH
SOLE
644069
0
0
Intra-Cellular Therapies, Inc.
Common
46116X101
9121873
172371
SH
SOLE
9121873
0
0
Intuitive Surgical, Inc.
Common
46120E602
29899638
112680
SH
SOLE
29899638
0
0
Ionis Pharmaceuticals, Inc.
Common
462222100
3317717
87840
SH
SOLE
3317717
0
0
IQVIA Holdings Inc.
Common
46266C105
12932042
63117
SH
SOLE
12932042
0
0
Ishares Biothechnology ETF
Common
464287556
3225664
24569
SH
SOLE
3225664
0
0
Jazz Pharmaceuticals plc
Shares
G50871105
29119000
182782
SH
SOLE
29119000
0
0
Johnson & Johnson
Common
478160104
112999295
639679
SH
SOLE
112999295
0
0
Karuna Therapeutics, Inc.
Common
48576A100
10503318
53452
SH
SOLE
10503318
0
0
Koninklijke Philips N.V.
NY Reg Shares
500472303
1646801
109860
SH
SOLE
1646801
0
0
Kura Oncology, Inc.
Common
50127T109
3515517
283281
SH
SOLE
3515517
0
0
Laboratory Corporation of America Holdings
Common
50540R409
10394558
44142
SH
SOLE
10394558
0
0
Lantheus Holdings, Inc.
Common
516544103
17472757
342872
SH
SOLE
17472757
0
0
LTC Properties, Inc.
Common
502175102
6476870
182293
SH
SOLE
6476870
0
0
Mallinckrodt plc
Shares
G5890A102
271622
35048
SH
SOLE
271622
0
0
McKesson Corp.
Common
58155Q103
24928600
66455
SH
SOLE
24928600
0
0
Medical Properties Trust, Inc.
Common
58463J304
4586817
411743
SH
SOLE
4586817
0
0
Medpace Holdings, Inc.
Common
58506Q109
2004088
9435
SH
SOLE
2004088
0
0
Medtronic plc
Shares
G5960L103
25350088
326172
SH
SOLE
25350088
0
0
Merck & Co., Inc.
Common
58933Y105
61257936
552122
SH
SOLE
61257936
0
0
Mereo BioPharma Group plc
ADS
589492107
1163312
1551082
SH
SOLE
1163312
0
0
Merus N.V.
Common
N5749R100
1428268
92325
SH
SOLE
1428268
0
0
Mirati Therapeutics, Inc.
Common
60468T105
2967352
65490
SH
SOLE
2967352
0
0
Moderna, Inc.
Common
60770K107
47586188
264927
SH
SOLE
47586188
0
0
Molina Healthcare, Inc.
Common
60855R100
24309145
73615
SH
SOLE
24309145
0
0
MoonLake Immunotherapeutics AG
Common
61559X104
3150000
300000
SH
SOLE
3150000
0
0
Morphic Holding, Inc.
Common
61775R105
1193719
44625
SH
SOLE
1193719
0
0
MorphoSys AG
Sponsored ADS
617760202
293084
81867
SH
SOLE
293084
0
0
Natera, Inc.
Common
632307104
1979256
49272
SH
SOLE
1979256
0
0
National Health Investors, Inc.
Common
63633D104
524184
10038
SH
SOLE
524184
0
0
Neurocrine Biosciences, Inc.
Common
64125C109
13485732
112908
SH
SOLE
13485732
0
0
NexGel, Inc.
Common
65344E107
5304
4243
SH
SOLE
5304
0
0
Nkarta, Inc.
Common
65487U108
173638
28988
SH
SOLE
173638
0
0
Novartis AG
Sponsored ADR
66987V109
12358332
136225
SH
SOLE
12358332
0
0
Novavax, Inc.
Common
670002401
655864
63800
SH
SOLE
655864
0
0
Novo Nordisk A/S
Sponsored ADR
670100205
17664983
130523
SH
SOLE
17664983
0
0
Omega Healthcare Investors, Inc.
Common
681936100
8564802
306433
SH
SOLE
8564802
0
0
Option Care Health, Inc.
Common
68404L201
1955098
64975
SH
SOLE
1955098
0
0
Perrigo Company plc
Shares
G97822103
1746226
51224
SH
SOLE
1746226
0
0
Pfizer Inc.
Common
717081103
74665391
1457170
SH
SOLE
74665391
0
0
Physicians Realty Trust
Common
71943U104
2441682
168741
SH
SOLE
2441682
0
0
Pliant Therapeutics, Inc.
Common
729139105
681054
35233
SH
SOLE
681054
0
0
Praxis Precision Medicines, Inc.
Common
74006W108
178500
75000
SH
SOLE
178500
0
0
Precision BioSciences, Inc.
Common
74019P108
267195
224534
SH
SOLE
267195
0
0
Prometheus Biosciences, Inc.
Common
74349U108
4206070
38237
SH
SOLE
4206070
0
0
Protagonist Therapeutics, Inc.
Common
74366E102
1333977
122271
SH
SOLE
1333977
0
0
Pyxis Oncology, Inc.
Common
747324101
949126
708303
SH
SOLE
949126
0
0
R1 RCM Inc.
Common
77634L105
2215743
202351
SH
SOLE
2215743
0
0
Rallybio Corporation
Common
75120L100
11346830
1727067
SH
SOLE
11346830
0
0
Regeneron Pharmaceuticals, Inc.
Common
75886F107
87200724
120862
SH
SOLE
87200724
0
0
Repare Therapeutics Inc.
Common
760273102
428797
29150
SH
SOLE
428797
0
0
ResMed Inc.
Common
761152107
12633283
60699
SH
SOLE
12633283
0
0
Sabra Health Care REIT, Inc.
Common
78573L106
6347504
510660
SH
SOLE
6347504
0
0
Sanofi
Sponsored ADR
80105N105
5978877
123454
SH
SOLE
5978877
0
0
Sarepta Therapeutics, Inc.
Common
803607100
18265467
140959
SH
SOLE
18265467
0
0
Scholar Rock Holding Corp.
Common
80706P103
984939
108833
SH
SOLE
984939
0
0
Seagen Inc.
Common
81181C104
14420621
112214
SH
SOLE
14420621
0
0
Smith & Nephew plc
Sponsored ADR
83175M205
4886182
181710
SH
SOLE
4886182
0
0
SPDR S&P Biotech ETF
S&P Biotech ETF
78464A870
12257191
147677
SH
SOLE
12257191
0
0
Spectrum Pharmaceuticals, Inc.
Common
84763A108
42256
114670
SH
SOLE
42256
0
0
STERIS plc
Shares
G8473T100
3078598
16669
SH
SOLE
3078598
0
0
Stevanato Group Societa' Per Azioni
Ordinary Shares
T9224W109
1279284
71190
SH
SOLE
1279284
0
0
Stryker Corp.
Common
863667101
40127655
164128
SH
SOLE
40127655
0
0
Sutro Biopharma, Inc.
Common
869367102
1192050
147531
SH
SOLE
1192050
0
0
Syndax Pharmaceuticals, Inc.
Common
87164F105
2995898
117717
SH
SOLE
2995898
0
0
Takeda Pharmaceutical Company Ltd.
Sponsored ADS
874060205
1639139
105073
SH
SOLE
1639139
0
0
Teva Pharmaceutical Industries Ltd.
Sponsored ADR
881624209
4192017
459651
SH
SOLE
4192017
0
0
Thermo Fisher Scientific Inc.
Common
883556102
51602406
93705
SH
SOLE
51602406
0
0
Theseus Pharmaceuticals, Inc.
Common
88369M101
498000
100000
SH
SOLE
498000
0
0
Travere Therapeutics, Inc.
Common
89422G107
8801476
418520
SH
SOLE
8801476
0
0
TScan Therapeutics, Inc.
Common
89854M101
326000
200000
SH
SOLE
326000
0
0
Ultragenyx Pharmaceutical Inc.
Common
90400D108
3107121
67065
SH
SOLE
3107121
0
0
uniQure N.V.
Shares
N90064101
14790951
652446
SH
SOLE
14790951
0
0
United Therapeutics Corp.
Common
91307C102
32001763
115077
SH
SOLE
32001763
0
0
Unitedhealth Group Inc.
Common
91324P102
143438078
270546
SH
SOLE
143438078
0
0
Universal Health Realty Income Trust
Common
91359E105
537344
11258
SH
SOLE
537344
0
0
Vaxcyte, Inc.
Common
92243G108
239750
5000
SH
SOLE
239750
0
0
VectivBio Holding AG
Common
H9060V101
6351631
737704
SH
SOLE
6351631
0
0
Ventas, Inc.
Common
92276F100
3003979
66681
SH
SOLE
3003979
0
0
Vertex Pharmaceuticals Inc.
Common
92532F100
95396452
330343
SH
SOLE
95396452
0
0
VYNE Therapeutics Inc.
Common
92941V209
20309
135395
SH
SOLE
20309
0
0
Welltower Inc.
Common
95040Q104
2719276
41484
SH
SOLE
2719276
0
0
Xencor, Inc.
Common
98401F105
5216541
200328
SH
SOLE
5216541
0
0
Xenon Pharmaceuticals Inc.
Common
98420N105
3300843
83714
SH
SOLE
3300843
0
0
Zai Lab Ltd.
ADR
98887Q104
1329310
43300
SH
SOLE
1329310
0
0
Zimmer Biomet Holdings, Inc.
Common
98956P102
33005670
258868
SH
SOLE
33005670
0
0
Zoetis Inc.
Class A
98978V103
20064747
136914
SH
SOLE
20064747
0
0