Chief Compliance Officer

0001104659-21-137799.txt : 20211112 0001104659-21-137799.hdr.sgml : 20211112 20211112115226 ACCESSION NUMBER: 0001104659-21-137799 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210930 FILED AS OF DATE: 20211112 DATE AS OF CHANGE: 20211112 EFFECTIVENESS DATE: 20211112 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 211401700 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE false false false 0001300336 XXXXXXXX 09-30-2021 09-30-2021 false Tekla Capital Management LLC

100 Federal Street 19th Floor Boston MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 11-12-2021 0 172 3105603 INFORMATION TABLE 2 infotable.xml 1Life Healthcare, Inc. Common 68269G107 633 31266 SH SOLE 31266 0 0 Abbott Laboratories Common 002824100 77616 657038 SH SOLE 657038 0 0 AbbVie Inc. Common 00287Y109 56547 524213 SH SOLE 524213 0 0 Adaptive Biotechnologies Corp. Common 00650F109 11479 337722 SH SOLE 337722 0 0 Addus HomeCare Corp. Common 006739106 6670 83632 SH SOLE 83632 0 0 Affimed N.V. Common N01045108 3622 586038 SH SOLE 586038 0 0 Agilent Technologies, Inc. Common 00846U101 6242 39625 SH SOLE 39625 0 0 Align Technology, Inc. Common 016255101 4963 7459 SH SOLE 7459 0 0 Alkermes plc Shares G01767105 11529 373824 SH SOLE 373824 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 35816 189695 SH SOLE 189695 0 0 ALX Oncology Holdings Inc. Common 00166B105 524 7099 SH SOLE 7099 0 0 Amgen Inc. Common 031162100 122256 574918 SH SOLE 574918 0 0 Amicus Therapeutics, Inc. Common 03152W109 5608 587277 SH SOLE 587277 0 0 Anthem, Inc. Common 036752103 5459 14644 SH SOLE 14644 0 0 Apellis Pharmaceuticals, Inc. Common 03753U106 6454 195820 SH SOLE 195820 0 0 ARCA biopharma, Inc. Common 00211Y506 96 32461 SH SOLE 32461 0 0 Arcutis Biotherapeutics, Inc. Common 03969K108 3145 131633 SH SOLE 131633 0 0 Ardelyx, Inc. Common 039697107 712 539408 SH SOLE 539408 0 0 Arena Pharmaceuticals, Inc. Common 040047607 4980 83629 SH SOLE 83629 0 0 argenx SE Sponsored ADR 04016X101 11614 38456 SH SOLE 38456 0 0 Arrowhead Pharmaceuticals, Inc. Common 04280A100 12749 204214 SH SOLE 204214 0 0 Arvinas, Inc. Common 04335A105 7067 85997 SH SOLE 85997 0 0 Ascendis Pharma A/S Sponsored ADR 04351P101 10806 67794 SH SOLE 67794 0 0 Assertio Holdings, Inc. Common 04546C205 372 410575 SH SOLE 410575 0 0 AstraZeneca plc Sponsored ADR 046353108 48824 812927 SH SOLE 812927 0 0 Atreca, Inc. Class A Common 04965G109 1429 229372 SH SOLE 229372 0 0 Aurinia Pharmaceuticals Inc. Common 05156V102 5595 252821 SH SOLE 252821 0 0 Becton, Dickinson and Company Common 075887109 10646 43307 SH SOLE 43307 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 23149 63772 SH SOLE 63772 0 0 Bellicum Pharmaceuticals, Inc. Common 079481404 18 6000 SH SOLE 6000 0 0 Bio-Techne Corp. Common 09073M104 2617 5400 SH SOLE 5400 0 0 Biogen Inc. Common 09062X103 66178 233853 SH SOLE 233853 0 0 Biohaven Pharmaceutical Holding Company Ltd. Common G11196105 12613 90799 SH SOLE 90799 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 9893 128004 SH SOLE 128004 0 0 BioNTech SE Sponsored ADS 09075V102 22046 80757 SH SOLE 80757 0 0 Black Diamond Therapeutics, Inc. Common 09203E105 1117 131990 SH SOLE 131990 0 0 Bolt Biotherapeutics, Inc. Common 097702104 823 65025 SH SOLE 65025 0 0 Boston Scientific Corp. Common 101137107 8068 185931 SH SOLE 185931 0 0 Bristol-Myers Squibb Company Common 110122108 36226 612236 SH SOLE 612236 0 0 Caribou Biosciences, Inc. Common 142038108 15621 699377 SH SOLE 699377 0 0 Catalent, Inc. Common 148806102 19151 143913 SH SOLE 143913 0 0 Charles River Laboratories International, Inc. Common 159864107 32388 78484 SH SOLE 78484 0 0 ChemoCentryx, Inc. Common 16383L106 1337 78197 SH SOLE 78197 0 0 Cigna Corp. Common 125523100 44383 221740 SH SOLE 221740 0 0 Codexis, Inc. Common 192005106 1871 80448 SH SOLE 80448 0 0 Community Health Systems, Inc. Common 203668108 1188 101535 SH SOLE 101535 0 0 Community Healthcare Trust Inc. Common 20369C106 673 14900 SH SOLE 14900 0 0 Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 422 413481 SH SOLE 413481 0 0 CRISPR Therapeutics AG Namen AKT H17182108 18170 162337 SH SOLE 162337 0 0 CVS Health Corp. Common 126650100 12513 147453 SH SOLE 147453 0 0 Danaher Corp. Common 235851102 45265 148683 SH SOLE 148683 0 0 Denali Therapeutics Inc. Common 24823R105 11221 222420 SH SOLE 222420 0 0 DENTSPLY SIRONA Inc. Common 24906P109 21335 367521 SH SOLE 367521 0 0 Dexcom, Inc. Common 252131107 23504 42980 SH SOLE 42980 0 0 Diversified Healthcare Trust Common 25525P107 1213 357720 SH SOLE 357720 0 0 Edwards Lifesciences Corp. Common 28176E108 22034 194630 SH SOLE 194630 0 0 Eli Lilly and Company Common 532457108 63639 275432 SH SOLE 275432 0 0 Endo International plc Shares G30401106 1603 494607 SH SOLE 494607 0 0 Exact Sciences Corp. Common 30063P105 21503 225282 SH SOLE 225282 0 0 Fate Therapeutics, Inc. Common 31189P102 4311 72727 SH SOLE 72727 0 0 Five Star Senior Living Inc. Common 33832D205 106 24237 SH SOLE 24237 0 0 Forma Therapeutics Holdings, Inc. Shares 34633R104 3474 149825 SH SOLE 149825 0 0 Fulcrum Therapeutics, Inc. Common 359616109 1238 43898 SH SOLE 43898 0 0 Fusion Pharmaceuticals Inc. Common 36118A100 344 43394 SH SOLE 43394 0 0 G1 Therapeutics, Inc. Common 3621LQ109 8379 624369 SH SOLE 624369 0 0 Galera Therapeutics, Inc. Common 36338D108 7277 898374 SH SOLE 898374 0 0 Gamida Cell Ltd. Shares M47364100 463 118142 SH SOLE 118142 0 0 Gilead Sciences, Inc. Common 375558103 119308 1708065 SH SOLE 1708065 0 0 Global Medical REIT Inc. Common 37954A204 2571 174897 SH SOLE 174897 0 0 Guardant Health, Inc. Common 40131M109 48502 387984 SH SOLE 387984 0 0 HCA Healthcare, Inc. Common 40412C101 27175 111961 SH SOLE 111961 0 0 Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 16909 132830 SH SOLE 132830 0 0 Healthcare Realty Trust Inc. Common 421946104 3098 104024 SH SOLE 104024 0 0 Healthcare Trust of America, Inc. Common 42225P501 2096 70662 SH SOLE 70662 0 0 Healthpeak Properties, Inc. Common 42250P103 5035 150392 SH SOLE 150392 0 0 Helix Acquisition Corp. Class A Common G4444C102 2468 250000 SH SOLE 250000 0 0 Hologic, Inc. Common 436440101 2092 28347 SH SOLE 28347 0 0 Horizon Therapeutics plc Shares G46188101 99719 910340 SH SOLE 910340 0 0 Humana Inc. Common 444859102 20677 53135 SH SOLE 53135 0 0 I-Mab Sponsored ADS 44975P103 11785 162580 SH SOLE 162580 0 0 Icon plc Shares G4705A100 25906 98871 SH SOLE 98871 0 0 IDEXX Laboratories, Inc. Common 45168D104 49542 79663 SH SOLE 79663 0 0 Illumina, Inc. Common 452327109 78673 193963 SH SOLE 193963 0 0 Intellia Therapeutics, Inc. Common 45826J105 7805 58180 SH SOLE 58180 0 0 Intercept Pharmaceuticals, Inc. Common 45845P108 773 52067 SH SOLE 52067 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 12094 324401 SH SOLE 324401 0 0 Intuitive Surgical, Inc. Common 46120E602 19885 20002 SH SOLE 20002 0 0 Ionis Pharmaceuticals, Inc. Common 462222100 10817 322521 SH SOLE 322521 0 0 IQVIA Holdings Inc. Common 46266C105 18359 76644 SH SOLE 76644 0 0 iTeos Therapeutics, Inc. Common 46565G104 1144 42362 SH SOLE 42362 0 0 Jazz Pharmaceuticals plc Shares G50871105 14852 114059 SH SOLE 114059 0 0 Johnson & Johnson Common 478160104 83439 516652 SH SOLE 516652 0 0 KalVista Pharmaceuticals, Inc. Common 483497103 1745 100000 SH SOLE 100000 0 0 Karuna Therapeutics, Inc. Common 48576A100 12289 100458 SH SOLE 100458 0 0 Koninklijke Philips N.V. NY Reg Shares 500472303 7323 164790 SH SOLE 164790 0 0 Kura Oncology, Inc. Common 50127T109 5122 273463 SH SOLE 273463 0 0 Laboratory Corporation of America Holdings Sponsored ADR 50540R409 26640 94656 SH SOLE 94656 0 0 LTC Properties, Inc. Common 502175102 5777 182293 SH SOLE 182293 0 0 McKesson Corp. Common 58155Q103 36203 181577 SH SOLE 181577 0 0 Medical Properties Trust, Inc. Common 58463J304 8264 411743 SH SOLE 411743 0 0 Medpace Holdings, Inc. Common 58506Q109 3572 18871 SH SOLE 18871 0 0 Medtronic plc Shares G5960L103 75301 600722 SH SOLE 600722 0 0 Merck & Co., Inc. Common 58933Y105 61313 816305 SH SOLE 816305 0 0 Mereo BioPharma Group plc ADS 589492107 3754 1551082 SH SOLE 1551082 0 0 Mettler-Toledo International Inc. Common 592688105 9159 6650 SH SOLE 6650 0 0 Mirati Therapeutics, Inc. Common 60468T105 14822 83784 SH SOLE 83784 0 0 Moderna, Inc. Common 60770K107 176826 459456 SH SOLE 459456 0 0 Molina Healthcare, Inc. Common 60855R100 22688 83625 SH SOLE 83625 0 0 Morphic Holding, Inc. Common 61775R105 1984 35025 SH SOLE 35025 0 0 MorphoSys AG Sponsored ADS 617760202 963 81867 SH SOLE 81867 0 0 National Health Investors, Inc. Common 63633D104 537 10038 SH SOLE 10038 0 0 Neurocrine Biosciences, Inc. Common 64125C109 11951 124609 SH SOLE 124609 0 0 Nkarta, Inc. Common 65487U108 806 28988 SH SOLE 28988 0 0 Novartis AG Sponsored ADR 66987V109 11140 136225 SH SOLE 136225 0 0 Novavax, Inc. Common 670002401 31406 151491 SH SOLE 151491 0 0 Novo Nordisk A/S Sponsored ADR 670100205 9188 95703 SH SOLE 95703 0 0 Omega Healthcare Investors, Inc. Common 681936100 9181 306433 SH SOLE 306433 0 0 Organon & Co. Common 68622V106 122 3717 SH SOLE 3717 0 0 Owens & Minor, Inc. Common 690732102 9230 294967 SH SOLE 294967 0 0 PerkinElmer, Inc. Common 714046109 5796 33444 SH SOLE 33444 0 0 Perrigo Company plc Shares G97822103 2424 51224 SH SOLE 51224 0 0 Pfizer Inc. Common 717081103 19371 450379 SH SOLE 450379 0 0 Physicians Realty Trust Common 71943U104 8735 495733 SH SOLE 495733 0 0 Praxis Precision Medicines, Inc. Common 74006W108 1387 75000 SH SOLE 75000 0 0 Precision BioSciences, Inc. Common 74019P108 727 63001 SH SOLE 63001 0 0 Protagonist Therapeutics, Inc. Common 74366E102 1528 86237 SH SOLE 86237 0 0 Qiagen N.V. Shares N72482123 5574 107855 SH SOLE 107855 0 0 R1 RCM Inc. Common 749397105 4454 202351 SH SOLE 202351 0 0 Rallybio Corp. Common 75120L100 37608 2308672 SH SOLE 2308672 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 89576 148015 SH SOLE 148015 0 0 ResMed Inc. Common 761152107 3740 14189 SH SOLE 14189 0 0 Sabra Health Care REIT, Inc. Common 78573L106 7517 510660 SH SOLE 510660 0 0 Sanofi Sponsored ADR 80105N105 7388 153254 SH SOLE 153254 0 0 Sarepta Therapeutics, Inc. Common 803607100 39444 426514 SH SOLE 426514 0 0 Scholar Rock Holding Corp. Common 80706P103 3594 108833 SH SOLE 108833 0 0 Seagen Inc. Common 81181C104 35205 207334 SH SOLE 207334 0 0 Smith & Nephew plc Sponsored ADR 83175M205 6240 181710 SH SOLE 181710 0 0 Spectrum Pharmaceuticals, Inc. Common 84763A108 250 114670 SH SOLE 114670 0 0 STERIS plc Shares G8473T100 3405 16669 SH SOLE 16669 0 0 Stevanato Group SpA Shares T9224W109 3490 137872 SH SOLE 137872 0 0 Stoke Therapeutics, Inc. Common 86150R107 2525 99263 SH SOLE 99263 0 0 Stryker Corp. Common 863667101 39690 150500 SH SOLE 150500 0 0 Sutro Biopharma, Inc. Common 869367102 7559 400147 SH SOLE 400147 0 0 Syneos Health, Inc. Class A 87166B102 21313 243633 SH SOLE 243633 0 0 Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3442 210146 SH SOLE 210146 0 0 TCR2 Therapeutics Inc. Common 87808K106 2007 235808 SH SOLE 235808 0 0 Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 5919 607651 SH SOLE 607651 0 0 Theravance Biopharma, Inc. Common G8807B106 4857 656296 SH SOLE 656296 0 0 Thermo Fisher Scientific Inc. Common 883556102 83480 146116 SH SOLE 146116 0 0 Travere Therapeutics, Inc. Common 89422G107 5162 212869 SH SOLE 212869 0 0 TScan Therapeutics, Inc. Common 89854M101 1668 200000 SH SOLE 200000 0 0 Turning Point Therapeutics, Inc. Common 90041T108 7927 119324 SH SOLE 119324 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 12692 140726 SH SOLE 140726 0 0 uniQure N.V. Shares N90064101 7587 237008 SH SOLE 237008 0 0 United Therapeutics Corp. Class B 91307C102 26753 144940 SH SOLE 144940 0 0 Unitedhealth Group Inc. Common 91324P102 119617 306129 SH SOLE 306129 0 0 Universal Health Realty Income Trust Shares 91359E105 622 11258 SH SOLE 11258 0 0 Universal Health Services, Inc. Class B 913903100 8305 60023 SH SOLE 60023 0 0 VectivBio Holding AG Shares H9060V101 5372 756502 SH SOLE 756502 0 0 Ventas, Inc. Common 92276F100 13699 248131 SH SOLE 248131 0 0 Verona Pharma plc Sponsored ADR 925050106 4120 751905 SH SOLE 751905 0 0 Vertex Pharmaceuticals Inc. Common 92532F100 49528 273046 SH SOLE 273046 0 0 Vir Biotechnology, Inc. Common 92764N102 3543 81400 SH SOLE 81400 0 0 VYNE Therapeutics Inc. Common 92941V209 188 135395 SH SOLE 135395 0 0 Waters Corp. Common 941848103 10169 28461 SH SOLE 28461 0 0 Welltower Inc. Common 95040Q104 16734 203083 SH SOLE 203083 0 0 West Pharmaceutical Services, Inc. Common 955306105 2649 6240 SH SOLE 6240 0 0 Xenon Pharmaceuticals Inc. Common 98420N105 2583 169030 SH SOLE 169030 0 0 Zai Lab Ltd. ADR 98887Q104 3955 37523 SH SOLE 37523 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 32595 222703 SH SOLE 222703 0 0 Zoetis Inc. Class A 98978V103 27684 142597 SH SOLE 142597 0 0 Zogenix, Inc. Common 98978L204 1352 88977 SH SOLE 88977 0 0