Chief Compliance Officer

0001104659-21-104973.txt : 20210813 0001104659-21-104973.hdr.sgml : 20210813 20210813142713 ACCESSION NUMBER: 0001104659-21-104973 CONFORMED SUBMISSION TYPE: 13F-HR PUBLIC DOCUMENT COUNT: 2 CONFORMED PERIOD OF REPORT: 20210630 FILED AS OF DATE: 20210813 DATE AS OF CHANGE: 20210813 EFFECTIVENESS DATE: 20210813 FILER: COMPANY DATA: COMPANY CONFORMED NAME: Tekla Capital Management LLC CENTRAL INDEX KEY: 0001300336 IRS NUMBER: 010628853 STATE OF INCORPORATION: DE FISCAL YEAR END: 0930 FILING VALUES: FORM TYPE: 13F-HR SEC ACT: 1934 Act SEC FILE NUMBER: 028-10950 FILM NUMBER: 211171489 BUSINESS ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 BUSINESS PHONE: 617 772-8500 MAIL ADDRESS: STREET 1: 100 FEDERAL STREET STREET 2: 19TH FLOOR CITY: BOSTON STATE: MA ZIP: 02110 FORMER COMPANY: FORMER CONFORMED NAME: Hambrecht & Quist Capital Management LLC DATE OF NAME CHANGE: 20040811 13F-HR 1 primary_doc.xml 13F-HR LIVE 0001300336 XXXXXXXX 06-30-2021 06-30-2021 false Tekla Capital Management LLC

100 FEDERAL STREET 19TH FLOOR BOSTON MA 02110

13F HOLDINGS REPORT 028-10950 N Laura Woodward Chief Compliance Officer 617-772-8500 /s/ Laura Woodward Boston MA 08-13-2021 0 189 3077338 false INFORMATION TABLE 2 a21-19641_1informationtable.xml INFORMATION TABLE 1Life Healthcare, Inc. Common 68269G107 1034 31266 SH SOLE 31266 0 0 Abbott Laboratories Common 002824100 87063 750997 SH SOLE 750997 0 0 AbbVie Inc. Common 00287Y109 69533 617303 SH SOLE 617303 0 0 ACADIA Pharmaceuticals Inc. Common 004225108 8092 331789 SH SOLE 331789 0 0 Adaptive Biotechnologies Corp. Common 00650F109 13799 337722 SH SOLE 337722 0 0 Addus HomeCare Corp. Common 006739106 4732 54237 SH SOLE 54237 0 0 Affimed N.V. Common N01045108 7724 908736 SH SOLE 908736 0 0 Agilent Technologies, Inc. Common 00846U101 7764 52525 SH SOLE 52525 0 0 Alexion Pharmaceuticals, Inc. Common 015351109 11841 64453 SH SOLE 64453 0 0 Align Technology, Inc. Common 016255101 6064 9925 SH SOLE 9925 0 0 Allakos Inc. Common 01671P100 11358 133045 SH SOLE 133045 0 0 Alnylam Pharmaceuticals, Inc. Common 02043Q107 22800 134495 SH SOLE 134495 0 0 Amedisys, Inc. Common 023436108 11774 48070 SH SOLE 48070 0 0 Amgen Inc. Common 031162100 112955 463405 SH SOLE 463405 0 0 Amicus Therapeutics, Inc. Common 03152W109 5993 621659 SH SOLE 621659 0 0 Anthem, Inc. Common 036752103 41133 107734 SH SOLE 107734 0 0 Apellis Pharmaceuticals, Inc. Common 03753U106 9640 152538 SH SOLE 152538 0 0 ARCA biopharma, Inc. Common 00211Y506 113 32461 SH SOLE 32461 0 0 Arcutis Biotherapeutics, Inc. Common 03969K108 3592 131633 SH SOLE 131633 0 0 Ardelyx, Inc. Common 039697107 4089 539408 SH SOLE 539408 0 0 Arena Pharmaceuticals, Inc. Common 040047607 13393 196385 SH SOLE 196385 0 0 argenx SE Sponsored ADR 04016X101 22403 74410 SH SOLE 74410 0 0 Arrowhead Pharmaceuticals, Inc. Common 04280A100 11006 132886 SH SOLE 132886 0 0 Arvinas, Inc. Common 04335A105 6622 85997 SH SOLE 85997 0 0 Ascendis Pharma A/S Sponsored ADR 04351P101 20211 153636 SH SOLE 153636 0 0 Assertio Holdings, Inc. Common 04546C205 640 410575 SH SOLE 410575 0 0 AstraZeneca PLC Sponsored ADR 046353108 26853 448298 SH SOLE 448298 0 0 Atreca, Inc. Class A Common 04965G109 3003 352424 SH SOLE 352424 0 0 Aurinia Pharmaceuticals Inc. Common 05156V102 5157 397920 SH SOLE 397920 0 0 Becton, Dickinson and Co. Common 075887109 10532 43307 SH SOLE 43307 0 0 BeiGene, Ltd. Sponsored ADR 07725L102 15781 45983 SH SOLE 45983 0 0 Bellicum Pharmaceuticals, Inc. Common 079481404 20 6000 SH SOLE 6000 0 0 Bio-Techne Corp. Common 09073M104 3422 7600 SH SOLE 7600 0 0 Biogen Inc. Common 09062X103 72413 209124 SH SOLE 209124 0 0 BioMarin Pharmaceutical Inc. Common 09061G101 10681 128004 SH SOLE 128004 0 0 BioNTech SE Sponsored ADS 09075V102 12778 57073 SH SOLE 57073 0 0 Black Diamond Therapeutics, Inc. Common 09203E105 1609 131990 SH SOLE 131990 0 0 Blueprint Medicines Corp. Common 09627Y109 10793 122699 SH SOLE 122699 0 0 Boston Scientific Corp. Common 101137107 7950 185931 SH SOLE 185931 0 0 BridgeBio Pharma, Inc. Common 10806X102 11507 188767 SH SOLE 188767 0 0 Bristol-Myers Squibb Co. Common 110122108 43832 655973 SH SOLE 655973 0 0 Catalent, Inc. Common 148806102 8652 80025 SH SOLE 80025 0 0 Celldex Therapeutics, Inc. Common 15117B202 236 7053 SH SOLE 7053 0 0 Centene Corp. Common 15135B101 4907 67290 SH SOLE 67290 0 0 Charles River Laboratories International, Inc. Common 159864107 20225 54674 SH SOLE 54674 0 0 ChemoCentryx, Inc. Common 16383L106 1047 78197 SH SOLE 78197 0 0 Cigna Corp. Common 125523100 50026 211018 SH SOLE 211018 0 0 Cogent Biosciences, Inc. Common 19240Q201 4361 537742 SH SOLE 537742 0 0 Community Health Systems, Inc. Common 203668108 1568 101535 SH SOLE 101535 0 0 Community Healthcare Trust Inc. Common 20369C106 707 14900 SH SOLE 14900 0 0 Corbus Pharmaceuticals Holdings, Inc. Common 21833P103 757 413481 SH SOLE 413481 0 0 CRISPR Therapeutics AG Namen AKT H17182108 26281 162337 SH SOLE 162337 0 0 CVS Health Corp. Common 126650100 12303 147453 SH SOLE 147453 0 0 CymaBay Therapeutics, Inc. Common 23257D103 384 88102 SH SOLE 88102 0 0 Danaher Corp. Common 235851102 44612 166240 SH SOLE 166240 0 0 Deciphera Pharmaceuticals, Inc. Common 24344T101 11265 307703 SH SOLE 307703 0 0 Denali Therapeutics Inc. Common 24823R105 11773 150086 SH SOLE 150086 0 0 DENTSPLY SIRONA Inc. Common 24906P109 24187 382344 SH SOLE 382344 0 0 Dexcom, Inc. Common 252131107 35336 82755 SH SOLE 82755 0 0 Dicerna Pharmaceuticals, Inc. Common 253031108 2543 68150 SH SOLE 68150 0 0 Diversified Healthcare Trust Common 25525P107 1495 357720 SH SOLE 357720 0 0 Editas Medicine, Inc. Common 28106W103 860 15190 SH SOLE 15190 0 0 Edwards Lifesciences Corp. Common 28176E108 22946 221555 SH SOLE 221555 0 0 Eli Lilly and Co. Common 532457108 58886 256561 SH SOLE 256561 0 0 Endo International plc Shares G30401106 2488 531570 SH SOLE 531570 0 0 Exact Sciences Corp. Common 30063P105 24819 199654 SH SOLE 199654 0 0 Exelixis, Inc. Common 30161Q104 9104 499657 SH SOLE 499657 0 0 Fate Therapeutics, Inc. Common 31189P102 6312 72727 SH SOLE 72727 0 0 Five Star Senior Living Inc. Common 33832D205 140 24237 SH SOLE 24237 0 0 Forma Therapeutics Holdings, Inc. Shares 34633R104 3729 149825 SH SOLE 149825 0 0 G1 Therapeutics, Inc. Common 3621LQ109 13699 624369 SH SOLE 624369 0 0 Galera Therapeutics, Inc. Common 36338D108 10241 1041845 SH SOLE 1041845 0 0 Gamida Cell Ltd. Shares M47364100 757 118142 SH SOLE 118142 0 0 Gilead Sciences, Inc. Common 375558103 112571 1634785 SH SOLE 1634785 0 0 Global Medical REIT Inc. Common 37954A204 2581 174897 SH SOLE 174897 0 0 Grifols, S.A. Sponsored ADR 398438408 822 47373 SH SOLE 47373 0 0 Guardant Health, Inc. Common 40131M109 19712 158727 SH SOLE 158727 0 0 HCA Healthcare, Inc. Common 40412C101 25789 124743 SH SOLE 124743 0 0 Health Care Select Sector SPDR Fund SBI Healthcare 81369Y209 23796 188930 SH SOLE 188930 0 0 Healthcare Realty Trust Inc. Common 421946104 3142 104024 SH SOLE 104024 0 0 Healthcare Trust of America, Inc. Common 42225P501 1887 70662 SH SOLE 70662 0 0 Healthpeak Properties, Inc. Common 42250P103 5007 150392 SH SOLE 150392 0 0 Helix Acquisition Corp. Class A Common G4444C102 2583 250000 SH SOLE 250000 0 0 Hologic, Inc. Common 436440101 2173 32564 SH SOLE 32564 0 0 Horizon Therapeutics plc Shares G46188101 87679 936340 SH SOLE 936340 0 0 Humana Inc. Common 444859102 25738 58135 SH SOLE 58135 0 0 I-Mab Sponsored ADS 44975P103 13649 162580 SH SOLE 162580 0 0 Icon plc Shares G4705A100 7515 36357 SH SOLE 36357 0 0 IDEXX Laboratories, Inc. Common 45168D104 21987 34814 SH SOLE 34814 0 0 Illumina, Inc. Common 452327109 95498 201809 SH SOLE 201809 0 0 Incyte Corp. Common 45337C102 9060 107687 SH SOLE 107687 0 0 Insmed Inc. Common 457669307 2800 98387 SH SOLE 98387 0 0 Intellia Therapeutics, Inc. Common 45826J105 9420 58180 SH SOLE 58180 0 0 Intercept Pharmaceuticals, Inc. Common 45845P108 1539 77067 SH SOLE 77067 0 0 Intra-Cellular Therapies, Inc. Common 46116X101 8276 202756 SH SOLE 202756 0 0 Intuitive Surgical, Inc. Common 46120E602 19585 21296 SH SOLE 21296 0 0 Ionis Pharmaceuticals, Inc. Common 462222100 12865 322521 SH SOLE 322521 0 0 Iovance Biotherapeutics, Inc. Common 462260100 12191 468538 SH SOLE 468538 0 0 IQVIA Holdings Inc. Common 46266C105 13756 56766 SH SOLE 56766 0 0 Jazz Pharmaceuticals plc Shares G50871105 11983 67456 SH SOLE 67456 0 0 Johnson & Johnson Common 478160104 85113 516652 SH SOLE 516652 0 0 Jounce Therapeutics, Inc. Common 481116101 2599 382237 SH SOLE 382237 0 0 KalVista Pharmaceuticals, Inc. Common 483497103 2396 100000 SH SOLE 100000 0 0 Karuna Therapeutics, Inc. Common 48576A100 11451 100458 SH SOLE 100458 0 0 Koninklijke Philips N.V. NY Reg Sh 500472303 2829 56927 SH SOLE 56927 0 0 Kura Oncology, Inc. Common 50127T109 5702 273463 SH SOLE 273463 0 0 Laboratory Corp. of America Holdings Sponsored ADR 50540R409 19413 70374 SH SOLE 70374 0 0 LTC Properties, Inc. Common 502175102 6998 182293 SH SOLE 182293 0 0 Madrigal Pharmaceuticals, Inc. Common 558868105 1299 13340 SH SOLE 13340 0 0 McKesson Corp. Common 58155Q103 28823 150715 SH SOLE 150715 0 0 Medical Properties Trust, Inc. Common 58463J304 8276 411743 SH SOLE 411743 0 0 Medpace Holdings, Inc. Common 58506Q109 3333 18871 SH SOLE 18871 0 0 Medtronic Plc Shares G5960L103 67865 546722 SH SOLE 546722 0 0 Merck & Co., Inc. Common 58933Y105 42128 541703 SH SOLE 541703 0 0 Mereo BioPharma Group plc ADS 589492107 3312 1044790 SH SOLE 1044790 0 0 Mettler-Toledo International Inc. Common 592688105 13576 9800 SH SOLE 9800 0 0 Mirati Therapeutics, Inc. Common 60468T105 13534 83784 SH SOLE 83784 0 0 Moderna, Inc. Common 60770K107 109448 465777 SH SOLE 465777 0 0 Molecular Templates, Inc. Common 608550109 1559 199420 SH SOLE 199420 0 0 Molina Healthcare, Inc. Common 60855R100 16097 63610 SH SOLE 63610 0 0 MorphoSys AG Sponsored ADS 617760202 1576 81867 SH SOLE 81867 0 0 National Health Investors, Inc. Common 63633D104 673 10038 SH SOLE 10038 0 0 Nektar Therapeutics Common 640268108 3096 180438 SH SOLE 180438 0 0 Neurocrine Biosciences, Inc. Common 64125C109 20719 212891 SH SOLE 212891 0 0 New Senior Investment Group Inc. Common 648691103 2251 256398 SH SOLE 256398 0 0 Nkarta, Inc. Common 65487U108 919 28988 SH SOLE 28988 0 0 Novartis AG Sponsored ADR 66987V109 12429 136225 SH SOLE 136225 0 0 Novavax, Inc. Common 670002401 18598 87596 SH SOLE 87596 0 0 Novo Nordisk A/S Sponsored ADR 670100205 4055 48406 SH SOLE 48406 0 0 Omega Healthcare Investors, Inc. Common 681936100 11120 306433 SH SOLE 306433 0 0 Organon & Co. Common 68622V106 1639 54169 SH SOLE 54169 0 0 Ovid Therapeutics Inc. Sponsored ADR 690469101 1457 372733 SH SOLE 372733 0 0 Owens & Minor, Inc. Common 690732102 11261 266023 SH SOLE 266023 0 0 PerkinElmer, Inc. Common 714046109 5728 37094 SH SOLE 37094 0 0 Perrigo Co. plc Shares G97822103 2349 51224 SH SOLE 51224 0 0 Personalis, Inc. Common 71535D106 4547 179731 SH SOLE 179731 0 0 Pfizer Inc. Common 717081103 17637 450379 SH SOLE 450379 0 0 Physicians Realty Trust Common 71943U104 9156 495733 SH SOLE 495733 0 0 PRA Health Sciences, Inc. Common 69354M108 4141 25068 SH SOLE 25068 0 0 Praxis Precision Medicines, Inc. Common 74006W108 1371 75000 SH SOLE 75000 0 0 Precision BioSciences, Inc. Common 74019P108 789 63001 SH SOLE 63001 0 0 R1 RCM Inc. Common 749397105 4500 202351 SH SOLE 202351 0 0 Reata Pharmaceuticals, Inc. Class A 75615P103 5409 38219 SH SOLE 38219 0 0 Regeneron Pharmaceuticals, Inc. Common 75886F107 77152 138132 SH SOLE 138132 0 0 REGENXBIO Inc. Common 75901B107 843 21700 SH SOLE 21700 0 0 Replimune Group, Inc. Common 76029N106 8416 219060 SH SOLE 219060 0 0 ResMed Inc. Common 761152107 33972 137807 SH SOLE 137807 0 0 Sabra Health Care REIT, Inc. Common 78573L106 9294 510660 SH SOLE 510660 0 0 Sage Therapeutics, Inc. Common 78667J108 6483 114119 SH SOLE 114119 0 0 Sanofi Sponsored ADR 80105N105 4295 81554 SH SOLE 81554 0 0 Sarepta Therapeutics, Inc. Common 803607100 15021 193224 SH SOLE 193224 0 0 Scholar Rock Holding Corp. Common 80706P103 3145 108833 SH SOLE 108833 0 0 Seagen Inc. Common 81181C104 33275 210759 SH SOLE 210759 0 0 Smith & Nephew plc Shares 83175M205 4677 107670 SH SOLE 107670 0 0 Spectrum Pharmaceuticals, Inc. Common 84763A108 430 114670 SH SOLE 114670 0 0 STERIS plc Shares G8473T100 5705 27655 SH SOLE 27655 0 0 Stryker Corp. Common 863667101 39089 150500 SH SOLE 150500 0 0 Sutro Biopharma, Inc. Common 869367102 7439 400147 SH SOLE 400147 0 0 Syneos Health, Inc. Class A 87166B102 21803 243633 SH SOLE 243633 0 0 Takeda Pharmaceutical Company Ltd. Sponsored ADS 874060205 3537 210146 SH SOLE 210146 0 0 TCR2 Therapeutics Inc. Common 87808K106 3870 235808 SH SOLE 235808 0 0 Teleflex Inc. Common 879369106 884 2200 SH SOLE 2200 0 0 Tetraphase Pharmaceuticals, Inc. Common 881CVR013 5 42965 SH SOLE 42965 0 0 Teva Pharmaceutical Industries Ltd. Sponsored ADR 881624209 6016 607651 SH SOLE 607651 0 0 Theravance Biopharma, Inc. Common G8807B106 9529 656296 SH SOLE 656296 0 0 Thermo Fisher Scientific Inc. Common 883556102 70691 140130 SH SOLE 140130 0 0 Travere Therapeutics, Inc. Common 89422G107 3106 212869 SH SOLE 212869 0 0 Trillium Therapeutics Inc. Common 89620X506 5133 529226 SH SOLE 529226 0 0 Turning Point Therapeutics, Inc. Common 90041T108 9310 119324 SH SOLE 119324 0 0 Ultragenyx Pharmaceutical Inc. Common 90400D108 12833 134590 SH SOLE 134590 0 0 uniQure N.V. Shares N90064101 6958 225921 SH SOLE 225921 0 0 United Therapeutics Corp. Class B 91307C102 25017 139438 SH SOLE 139438 0 0 Unitedhealth Group Inc. Common 91324P102 126358 315548 SH SOLE 315548 0 0 Universal Health Realty Income Trust Shares 91359E105 693 11258 SH SOLE 11258 0 0 Universal Health Services, Inc. Class B 913903100 8789 60023 SH SOLE 60023 0 0 Vectivbio Holding AG Ord Shares H9060V101 1691 145000 SH SOLE 145000 0 0 Ventas, Inc. Common 92276F100 11883 208108 SH SOLE 208108 0 0 Verona Pharma plc Sponsored ADR 925050106 4917 751905 SH SOLE 751905 0 0 Vertex Pharmaceuticals Inc. Common 92532F100 79702 395288 SH SOLE 395288 0 0 Vir Biotechnology, Inc. Common 92764N102 3849 81400 SH SOLE 81400 0 0 VYNE Therapeutics Inc. Common 92941V209 475 135395 SH SOLE 135395 0 0 Waters Corp. Common 941848103 16695 48306 SH SOLE 48306 0 0 Welltower Inc. Common 95040Q104 16876 203083 SH SOLE 203083 0 0 Xenon Pharmaceuticals Inc. Common 98420N105 3147 169030 SH SOLE 169030 0 0 Y-mAbs Therapeutics, Inc. Common 984241109 6686 197820 SH SOLE 197820 0 0 Zai Lab Ltd. ADR 98887Q104 6641 37523 SH SOLE 37523 0 0 Zimmer Biomet Holdings, Inc. Common 98956P102 35815 222703 SH SOLE 222703 0 0 Zoetis Inc. Class A 98978V103 10533 56521 SH SOLE 56521 0 0 Zogenix, Inc. Common 98978L204 1538 88977 SH SOLE 88977 0 0