| Item 1. | |
| (a) | Name of issuer:
Pacific Biosciences of California, Inc. |
| (b) | Address of issuer's principal executive offices:
1305 O'Brien Drive, Menlo Park, California 94025 |
| Item 2. | |
| (a) | Name of person filing:
This Schedule 13G is being filed on behalf of each of the following persons (each, a "Reporting Person") :
1. EDMOND DE ROTHSCHILD ASSET MANAGEMENT (FRANCE) ("EDRAM France")
2. EDMOND DE ROTHSCHILD ASSET MANAGEMENT (LUXEMBOURG) ("EDRAM Luxembourg")
3. Edmond de Rothschild Fund ("EdR Fund") |
| (b) | Address or principal business office or, if none, residence:
The address of EDRAM France is 47, RUE DU FAUBOURG SAINT HONORE PARIS, France 75008.
The address of EDRAM Luxembourg is 4, RUE ROBERT STUMPER, Luxembourg L-2557.
The address of EdR Fund is 4, Rue Robert Stumper, Luxembourg L-2557. |
| (c) | Citizenship:
EDRAM France is a French entity
EDRAM Luxembourg is a Luxembourg entity
EdR Fund is a societe d'investissement a capital variable (SICAV) Luxembourg formed under the laws of Luxembourg. |
| (d) | Title of class of securities:
Common Stock |
| (e) | CUSIP No.:
69404D108 |
| Item 3. | If this statement is filed pursuant to §§ 240.13d-1(b) or 240.13d-2(b) or (c), check whether the person filing is a: |
| (a) |  Broker or dealer registered under section 15 of the Act (15 U.S.C. 78o);
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| (b) | Bank as defined in section 3(a)(6) of the Act (15 U.S.C. 78c);
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| (c) | Insurance company as defined in section 3(a)(19) of the Act (15 U.S.C. 78c);
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| (d) | Investment company registered under section 8 of the Investment Company Act of 1940 (15 U.S.C. 80a-8);
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| (e) | An investment adviser in accordance with § 240.13d-1(b)(1)(ii)(E);
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| (f) | An employee benefit plan or endowment fund in accordance with § 240.13d-1(b)(1)(ii)(F);
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| (g) | A parent holding company or control person in accordance with § 240.13d-1(b)(1)(ii)(G);
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| (h) | A savings associations as defined in Section 3(b) of the Federal Deposit Insurance Act (12 U.S.C. 1813);
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| (i) | A church plan that is excluded from the definition of an investment company under section 3(c)(14) of the Investment Company Act of 1940 (15 U.S.C. 80a-3);
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| (j) |  A non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J). If filing as a non-U.S. institution in accordance with § 240.13d-1(b)(1)(ii)(J),
please specify the type of institution:
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| (k) | Group, in accordance with Rule 240.13d-1(b)(1)(ii)(K).
|
| | investment manager |
| Item 4. | Ownership |
| (a) | Amount beneficially owned:
Ownership as of June 30, 2025 is incorporated by reference to items (5) - (9) and (11) of the cover page of each Reporting Person. Both EDRAM France and EDRAM Luxembourg, management companies, may be deemed to have beneficial ownership of the securities which are the subject of this filing through the investment and/or voting discretion it exercises over its portfolios managed. |
| (b) | Percent of class:
See the response(s) to Item 11 on the attached cover page(s). |
| (c) | Number of shares as to which the person has:
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| | (i) Sole power to vote or to direct the vote:
See the response(s) to Item 5 on the attached cover page(s).
|
| | (ii) Shared power to vote or to direct the vote:
See the response(s) to Item 6 on the attached cover page(s).
|
| | (iii) Sole power to dispose or to direct the disposition of:
See the response(s) to Item 7 on the attached cover page(s).
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| | (iv) Shared power to dispose or to direct the disposition of:
See the response(s) to Item 8 on the attached cover page(s).
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| Item 5. | Ownership of 5 Percent or Less of a Class. |
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Ownership of 5 percent or less of a class
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| Item 6. | Ownership of more than 5 Percent on Behalf of Another Person. |
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Not Applicable
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| Item 7. | Identification and Classification of the Subsidiary Which Acquired the Security Being Reported on by the Parent Holding Company or Control Person. |
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Not Applicable
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| Item 8. | Identification and Classification of Members of the Group. |
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Not Applicable
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| Item 9. | Notice of Dissolution of Group. |
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Not Applicable
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