X0306 4 2014-11-10 0 0001059790 POZEN INC /NC POZN 0001298628 Hodges William L C/O POZEN INC. 1414 RALEIGH ROAD, SUITE 400 CHAPEL HILL NC 27517 0 1 0 0 Sr. VP Finance, CFO Common Stock 2014-11-10 4 M 0 15268 4.64 A 81729 D Common Stock 2014-11-10 4 M 0 20154 5.33 A 101883 D Common Stock 2014-11-10 4 M 0 4978 3.77 A 106861 D Common Stock 2014-11-10 4 F 0 20762 9.49 D 86099 D Stock Option 4.64 2014-11-10 4 M 0 15268 0.00 D 2019-03-13 Common Stock 15268 45807 D Stock Option 5.33 2014-11-10 4 M 0 20154 0.00 D 2020-03-15 Common Stock 20154 40921 D Stock Option 3.77 2014-11-10 4 M 0 4978 0.00 D 2021-03-15 Common Stock 4978 36248 D Represents shares of the Registrant's common stock delivered as payment of exercise price in connection with the net exercise of stock options by the reporting person on November 10, 2014. Such shares are to be delivered to the Registrant's treasury account. Reflects the closing stock price on November 10, 2014 of $9.49, as reported by the NASDAQ Stock Market. The option vested in four equal annual installments, with the initial vesting date occurring on March 13, 2010. The option vested in four equal annual installments, with the initial vesting date occurring on March 15, 2011. The option vest in four equal annual installments, with the initial vesting date occurring on March 15, 2011. /s/ John E. Barnhardt, Attorney-in-fact 2014-11-12