<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0001298528</cik>
        <entityName>Artielle ImmunoTherapeutics Inc</entityName>
        <issuerAddress>
            <street1>9020 SW Washington Square Road</street1>
            <street2>Suite 450</street2>
            <city>Tigard</city>
            <stateOrCountry>OR</stateOrCountry>
            <stateOrCountryDescription>OREGON</stateOrCountryDescription>
            <zipCode>97223</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>503 626-1144</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <edgarPreviousNameList>
            <previousName>Artielle Immuno Therapeutics Inc</previousName>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Adolph</firstName>
                <middleName>J.</middleName>
                <lastName>Ferro</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>9020 SW Washington Square Road</street1>
                <street2>Suite 450</street2>
                <city>Tigard</city>
                <stateOrCountry>OR</stateOrCountry>
                <stateOrCountryDescription>OREGON</stateOrCountryDescription>
                <zipCode>97223</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gilbert</firstName>
                <middleName>N.</middleName>
                <lastName>Miller</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>9020 SW Washington Square Road</street1>
                <street2>Suite 450</street2>
                <city>Tigard</city>
                <stateOrCountry>OR</stateOrCountry>
                <stateOrCountryDescription>OREGON</stateOrCountryDescription>
                <zipCode>97223</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Shahab</firstName>
                <lastName>Fatheazam</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>9020 SW Washington Square Road</street1>
                <street2>Suite 450</street2>
                <city>Tigard</city>
                <stateOrCountry>OR</stateOrCountry>
                <stateOrCountryDescription>OREGON</stateOrCountryDescription>
                <zipCode>97223</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Peter</firstName>
                <lastName>McWilliams</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Sanderling Ventures</street1>
                <street2>400 South El Camino Real, Suite 1200</street2>
                <city>San Mateo</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>94402-1708</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Paul</firstName>
                <lastName>Quadros</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Tenex Greenhouse Ventures LLC</street1>
                <street2>533 Airport Blvd., Ste 400</street2>
                <city>Burlingame</city>
                <stateOrCountry>CA</stateOrCountry>
                <stateOrCountryDescription>CALIFORNIA</stateOrCountryDescription>
                <zipCode>94010</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Allan</firstName>
                <lastName>Wolfe</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Utah Ventures, 2755 E. Cottonwood</street1>
                <street2>Parkway, Suite 520</street2>
                <city>Salt Lake City</city>
                <stateOrCountry>UT</stateOrCountry>
                <stateOrCountryDescription>UTAH</stateOrCountryDescription>
                <zipCode>84121</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>J.</firstName>
                <middleName>Brock</middleName>
                <lastName>Metcalf</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>c/o Reference Capital Management LLC</street1>
                <street2>12909 SW 68th Parkway, Suite 430</street2>
                <city>Portland</city>
                <stateOrCountry>OR</stateOrCountry>
                <stateOrCountryDescription>OREGON</stateOrCountryDescription>
                <zipCode>97223</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Biotechnology</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-08-23</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isDebtType>true</isDebtType>
            <isOptionToAcquireType>true</isOptionToAcquireType>
            <isSecurityToBeAcquiredType>true</isSecurityToBeAcquiredType>
            <isOtherType>true</isOtherType>
            <descriptionOfOtherType>1) Convertible Promissory Notes, the underlying shares of Preferred Stock and Common Stock isued on conversion thereof: 2) Common Stock Warrants and the underlying shares of Common Stock issuable upon exercise.</descriptionOfOtherType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>0</minimumInvestmentAccepted>
        <salesCompensationList></salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>100000</totalOfferingAmount>
            <totalAmountSold>100000</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>5</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>0</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>false</authorizedRepresentative>
            <signature>
                <issuerName>Artielle ImmunoTherapeutics Inc</issuerName>
                <signatureName>/s/ Gilbert N. Miller</signatureName>
                <nameOfSigner>Gilbert N. Miller</nameOfSigner>
                <signatureTitle>Executive Vice President</signatureTitle>
                <signatureDate>2010-09-07</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
