Exhibit 99.1

JOINT FILING AGREEMENT OF

NOVARTIS BIOVENTURES LTD.

AND

NOVARTIS AG

The undersigned persons agree and consent pursuant to Rule 13d-1(k)(1) under the Securities Exchange Act of 1934, as amended, as of the date set forth below, to the joint filing on their behalf of the Amendment to Schedule 13D to which this Exhibit is attached, in connection with their beneficial ownership of the common stock of Marina Biotech, Inc. at January 25, 2011 and agree that such statement is filed on behalf of each of them.

	NOVARTIS BIOVENTURES LTD.
Dated: January 26, 2011	/s/ Henri Simon Zivi
	By: Henri Simon Zivi
	Title: Deputy Chairman
Dated: January 26, 2011	/s/ Hanna Szepietowska
	By: Hanna Szepietowska
	Title: Authorized Signatory
	NOVARTIS AG
Dated: January 26, 2011	/s/ Bruno Heynen
	By: Bruno Heynen
	Title: Authorized Signatory
Dated: January 26, 2011	/s/ Felix Senn
	By: Felix Senn
	Title: Authorized Signatory