<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0206</schemaVersion>

    <documentType>3/A</documentType>

    <periodOfReport>2014-06-24</periodOfReport>

    <dateOfOriginalSubmission>2014-06-24</dateOfOriginalSubmission>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0001297184</issuerCik>
        <issuerName>Amphastar Pharmaceuticals, Inc.</issuerName>
        <issuerTradingSymbol>AMPH</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001611148</rptOwnerCik>
            <rptOwnerName>Shandell Jason B.</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O AMPHASTAR PHARMACEUTICALS, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>11570 6TH STREET</rptOwnerStreet2>
            <rptOwnerCity>RANCHO CUCAMONGA</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>91730</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
            <officerTitle>President</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>3332</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The reported shares are represented by deferred stock units, or DSUs, which vest in five equal annual installments beginning on August 2, 2010.</footnote>
        <footnote id="F2">This amended Form 3 is filed to correct the amount of DSUs held by the reporting person. The prior Form 3 reported 666 DSUs. This error in column 2 of Table I also appears in subsequent Forms 4 filed through October 6, 2015.</footnote>
    </footnotes>

    <remarks></remarks>

    <ownerSignature>
        <signatureName>/s/ Ken Stupak, by power of attorney</signatureName>
        <signatureDate>2016-02-03</signatureDate>
    </ownerSignature>
</ownershipDocument>
