X0306 4 2018-10-19 0 0001459839 SI-BONE, Inc. SIBN 0001296771 Freund John Gordon C/O SKYLINE VENTURES 525 UNIVERSITY AVENUE, SUITE 1350 PALO ALTO CA 94301 1 0 1 0 Common Stock 2018-10-19 4 C 0 2213425 A 2213425 I By Skyline Venture Partners V, L.P. Common Stock 2018-10-19 4 C 0 792195 A 3005620 I By Skyline Venture Partners V, L.P. Common Stock 2018-10-19 4 C 0 690689 A 3696309 I By Skyline Venture Partners V, L.P. Common Stock 2018-10-19 4 C 0 398676 A 4094985 I By Skyline Venture Partners V, L.P. Common Stock 2018-10-19 4 P 0 325000 15.00 A 4419985 I By Skyline Venture Partners V, L.P. Warrant (right to buy) 9.10 2018-10-19 4 X 0 39421 0.00 D Series 5 Preferred Stock 39421 0 I By Skyline Venture Partners V, L.P. Series 5 Preferred Stock 9.10 2018-10-19 4 X 0 39421 0.00 A Common Stock 39421 816099 I By Skyline Venture Partners V, L.P. Series 5 Preferred Stock 2018-10-19 4 S 0 23904 15.00 D Common Stock 23904 792195 I By Skyline Venture Partners V, L.P. Series 4 Preferred Stock 2018-10-19 4 C 0 2213425 D Common Stock 2213425 0 I By Skyline Venture Partners V, L.P. Series 5 Preferred Stock 2018-10-19 4 C 0 792195 D Common Stock 792195 0 I By Skyline Venture Partners V, L.P. Series 6 Preferred Stock 2018-10-19 4 C 0 652347 D Common Stock 690689 0 I By Skyline Venture Partners V, L.P. Series 7 Preferred Stock 2018-10-19 4 C 0 398676 D Common Stock 398676 0 I By Skyline Venture Partners V, L.P. The Issuer's Series 4 Preferred Stock, Series 5 Preferred Stock and Series 7 Preferred Stock automatically converted into an equal number of shares of Issuer's common stock immediately upon the closing of the Issuer's initial public offering and has no expiration date. Shares held by Skyline Venture Partners V, L.P. ("SVP V"). Skyline Venture Management V, LLC ("LLC") is the general partner of SVP V and as such may be deemed to have voting and investment power with respect to the securities of SVP V. Dr. Freund, a member of the Issuer's board of directors, together with Yasunori Kaneko, are the managing directors of LLC and each may be deemed to have voting and investment power with respect to the securities held by SVP V. Dr. Freund disclaims beneficial ownership of such securities, except to the extent of his pecuniary interest therein. The Issuer's Series 6 Preferred Stock automatically converted into approximately 1.05878 shares of Issuer's common stock immediately upon the closing of the Issuer's initial public offering and has no expiration date. Shares subject to the warrant are immediately exercisable. The warrant will expire in connection with the closing of the Issuer's initial public offering. Immediately prior to the closing of the Issuer's initial public offering, SVP V exercised a warrant to purchase 39,421 shares of Series 5 Preferred Stock at an exercise price of $9.10 per share. The exercise price was paid on a net exercise cashless basis calculated using the Issuer's initial public offering price of $15.00, resulting in the Issuer withholding 23,904 of the warrant shares to pay the exercise price and issuing SVP V the remaining 15,517 shares. /s/ Michael A. Pisetsky, Attorney-in-Fact for John G. Freund 2018-10-19