X0306 4 2016-12-29 1 0001251769 LPATH, INC LPTN 0001294939 Petree Daniel H C/O LPATH, INC. 4025 SORRENTO VALLEY BLVD. SAN DIEGO CA 92121 1 0 0 0 The reporting person has resigned as a director of the Issuer. As a result, the reporting person is no longer subject to Section 16 in connection with his transactions in the equity securities of the Issuer and therefore will no longer report any such transactions on Form 4 or Form 5. /s/ Daniel Petree 2016-12-29