X0306 4 2018-09-27 0 0001174940 ORAGENICS INC OGEN 0001294887 Joslyn Alan 4902 EISENHOWER BOULEVARD TAMPA FL 33634 1 1 0 0 See Remarks Employee Stock Option (Right to Buy) 0.73 2018-09-27 4 A 0 400000 0.00 A 2018-09-27 2028-09-27 Common Stock 400000 400000 D Represents an award of options to purchase shares of the Company's common stock under the Company's 2012 Equity Incentive Plan, as amended that vest evenly in three tranches. One third of the options vest immediately, the second third of the options vest on the first anniversary of the grant date and the final third vest on the second anniversary of the grant date. The option exercise price is the closing price on the date of the grant, September 27, 2018. Chief Executive Officer and President /s/ Mark A. Catchur, as Attorney-in-Fact for Alan Joslyn 2018-10-01