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Collaborative arrangements - Changes in Balances of Company's Receivables and Contract Liabilities (Detail)
$ in Thousands
9 Months Ended
Sep. 30, 2018
USD ($)
Contract liabilities:  
Deductions $ (32,000)
Celgene Corporation [Member]  
Receivables  
Balance at beginning of period under Topic 606 4,635
Additions 1,641
Deductions (6,276)
Contract liabilities:  
Balance at beginning of period under Topic 606 76,812
Deductions (31,981)
Balance at end of period under Topic 606 44,831
Celgene Corporation [Member] | Accrued Expenses [Member]  
Contract liabilities:  
Additions 8,031
Deductions (2,824)
Balance at end of period under Topic 606 $ 5,207