Property, plant and equipment, net

3 Months Ended

Mar. 31, 2018

Property Plant And Equipment [Abstract]

5. Property, plant and equipment, net

Property, plant and equipment, net, consists of the following (in thousands):

	As of			As of
	March 31, 2018			December 31, 2017
Land	$	1,210		$	1,210
Building		165,562			164,414
Computer equipment and software		5,428			5,134
Office equipment		4,808			4,478
Laboratory equipment		28,291			24,914
Leasehold improvements		116			116
Construction-in-progress		17,744			15,189
Total property, plant and equipment		223,159			215,455
Less accumulated depreciation and amortization		(18,929	)		(15,849	)
Property, plant and equipment, net	$	204,230		$	199,606

North Carolina manufacturing facility

In November 2017, the Company acquired a manufacturing facility, which is in the process of construction, in Durham, North Carolina for the future manufacture of lentiviral vector for the Company’s gene and cell therapies. Construction-in-progress as of March 31, 2018 and December 31, 2017 includes $16.3 million and $12.9 million, respectively, related to the North Carolina manufacturing facility.

60 Binney Street lease

As of March 31, 2018, total property, plant and equipment, gross, includes $165.6 million related to the Company’s headquarters at 60 Binney Street in Cambridge, Massachusetts, of which $156.0 million was incurred by the landlord. As of December 31, 2017, total property, plant and equipment, gross, includes $164.4 million related to the Company’s headquarters at 60 Binney Street in Cambridge, Massachusetts, of which $156.0 million was incurred by the landlord. Please refer to Note 7, "Commitments and contingencies" for further information.