Accrued expenses and other current liabilities - Summary of Accrued Expenses and Other Current Liabilities (Detail) - USD ($) $ in Thousands	Mar. 31, 2017	Dec. 31, 2016
Payables And Accruals [Abstract]
Employee compensation	$ 6,251	$ 11,296
Accrued goods and services	29,538	34,275
Accrued license and milestone fees	285	2,464
Accrued professional fees	1,393	1,492
Deferred rent, current portion		11
Contingent consideration, current portion	6,059	4,479
Other	781	643
Total accrued expenses and other current liabilities	$ 44,307	$ 54,660