Property and equipment, net (Tables)

12 Months Ended

Dec. 31, 2016

Property Plant And Equipment [Abstract]

Property and equipment

Property and equipment, net, consists of the following (in thousands):

	December 31,
	2016			2015
Computer equipment and software	$	1,655		$	1,259
Office equipment		1,427			1,104
Laboratory equipment		16,305			10,520
Leasehold improvements		13,697			11,010
Construction-in-progress		136,315			65,542
Total property and equipment		169,399			89,435
Less accumulated depreciation and amortization		(12,444	)		(6,821	)
Property and equipment, net	$	156,955		$	82,614