Represents the total amount of collaborative arrangement consideration allocated to all deliverables.

No definition available.

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- Definition

Collaborative arrangement term of agreement.

+ References

No definition available.

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- Definition

Deferred revenue expected to be recognized.

+ References

No definition available.

+ Details

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- Definition

Deferred revenue recognition period.

+ References

No definition available.

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- Definition

Delivered deliverables in arrangement.

+ References

No definition available.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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- Definition

Amount of billed or unbilled claims or other similar items subject to uncertainty concerning their determination or ultimate realization under long-term contracts.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 210
-SubTopic 10
-Section S99
-Paragraph 1
-Subparagraph (SX 210.5-02.3(c)(3))
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- Definition

Amount of deferred revenue as of balance sheet date. Deferred revenue represents collections of cash or other assets related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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-Section S99
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-Publisher SEC
-Name Staff Accounting Bulletin (SAB)
-Number Topic 13
-Section A

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- Definition

Amount of deferred revenue recognized for transactions arising during the current reporting period. Deferred revenue is a liability as of the balance sheet date related to a revenue producing activity for which revenue has not yet been recognized. Generally, an Entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
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- Definition

Amount of previously reported deferred or unearned revenue that was recognized as revenue during the period. Deferred revenue is a liability related to a revenue producing activity for which revenue has not yet been recognized. Generally, an entity records deferred revenue when it receives consideration from a customer before achieving certain criteria that must be met for revenue to be recognized in conformity with GAAP.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
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-Name Accounting Standards Codification
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-Name Staff Accounting Bulletin (SAB)
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Significant agreements - Additional Information (Detail) - Celgene Corporation [Member]			12 Months Ended
	Jun. 03, 2015 USD ($) Deliverables	Mar. 19, 2013 USD ($)	Dec. 31, 2015 USD ($)	Dec. 31, 2014 USD ($)	Dec. 31, 2013 USD ($)
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Term of collaboration agreement		3 years
First Product Candidates [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	$ 10,000,000
Additional Product Candidates [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	15,000,000
Co-Develop and Co-Promote Options not Exercise [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	10,000,000
Maximum [Member] \| Clinical Milestone Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	10,000,000
Maximum [Member] \| Regulatory Milestone Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	117,000,000
Maximum [Member] \| Commercial Milestones Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	$ 78,000,000
Collaborative Arrangement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Number of deliverable \| Deliverables	3
Consideration allocated to agreement			$ 109,000,000
Deferred revenue recognition period			3 years
Deferred revenue recognized			$ 14,100,000	$ 25,000,000	$ 19,800,000
Deferred revenue			41,800,000	$ 30,700,000
Deferred revenue expected to be recognized			14,200,000
Collaborative Arrangement [Member] \| Option Fee [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event			10,000,000
Collaborative Arrangement [Member] \| Delivered Elements [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaboration agreement, cash payment received	$ 20,000,000
Consideration allocated to agreement			17,300,000
Collaborative Arrangement, Co-promotion and Development [Member] \| Maximum [Member] \| Clinical Milestone Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	10,000,000
Collaborative Arrangement, Co-promotion and Development [Member] \| Maximum [Member] \| Regulatory Milestone Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	54,000,000
Collaborative Arrangement, Co-promotion and Development [Member] \| Maximum [Member] \| Commercial Milestones Payments [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Amount per product eligible to be received upon achievement of specified event	36,000,000
Up-front Payment Arrangement [Member] \| Collaborative Arrangement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaboration agreement, cash payment received		$ 75,000,000	25,000,000
Up-front Payment Arrangement [Member] \| Amended Collaborative Arrangement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Collaboration agreement, cash payment received	$ 25,000,000
Manufacturing Services \| Collaborative Arrangement [Member]
Collaborative Arrangements And Noncollaborative Arrangement Transactions [Line Items]
Consideration allocated to agreement			$ 54,100,000