Description of the business (Details) $ in Thousands, shares in Millions			1 Months Ended				3 Months Ended						9 Months Ended
	Dec. 22, 2023 USD ($)	Dec. 19, 2023 shares	Sep. 30, 2024 USD ($) employee	Mar. 31, 2024 USD ($) tranche	Dec. 31, 2023 USD ($) shares	Aug. 31, 2023 USD ($)	Sep. 30, 2024 USD ($)	Jun. 30, 2024 USD ($)	Mar. 31, 2024 USD ($) tranche	Sep. 30, 2023 USD ($)	Jun. 30, 2023 USD ($)	Mar. 31, 2023 USD ($)	Sep. 30, 2024 USD ($)	Sep. 30, 2023 USD ($)
Subsidiary, Sale of Stock [Line Items]
Number of tranches | tranche				4					4
Number of employees eliminated | employee			94
Plans to reduce workforce, as a percent			25.00%
Accumulated deficit			$ 4,472,333		$ 4,260,328		$ 4,472,333						$ 4,472,333
Net income (loss)							60,808	$ 81,393	$ 69,804	$ 87,232	$ 62,789	$ (18,930)	212,003	$ 131,091
Net cash used in operating activities													209,856	$ 180,910
Cash, cash equivalents and marketable securities			$ 70,700				$ 70,700						$ 70,700
Term Loan
Subsidiary, Sale of Stock [Line Items]
Debt instrument term				5 years
Line of credit				$ 175,000					$ 175,000
At The Market Offering
Subsidiary, Sale of Stock [Line Items]
Proceeds from stock offering						$ 125,000
December Underwriting Agreement
Subsidiary, Sale of Stock [Line Items]
Proceeds from stock offering	$ 118,100				$ 118,100
Shares of common stock sold (in shares) | shares		83.3			83.3