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Product revenue and reserves (Tables)
 9 Months Ended
Sep. 30, 2024
Revenue from Contract with Customer [Abstract]  
Disaggregation of Revenue Product revenue by therapy represents:
For the three months ended
September 30,		For the nine months ended
September 30,
2024202320242023
ZYNTEGLO$5,493 $4,851 $35,212 $9,031 
LYFGENIA2,632 — 2,632 — 
SKYSONA2,487 7,430 7,430 12,383 
Total product revenue, net
$10,612 $12,281 $45,274 $21,414 
Summary of Contract with Customer, Refund Liability
The following table summarizes an analysis of the change in reserves for gross to net deductions for the periods indicated:
Total
Balance at December 31, 2023
$5,365 
Provision for rebates
8,506 
Payments/credits— 
Balance at September 30, 2024
$13,871