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Stock-based compensation (Tables)
 6 Months Ended
Jun. 30, 2024
Share-Based Payment Arrangement [Abstract]  
Summary of Stock-Based Compensation Expense by Award Type Stock-based compensation expense recognized by award type is included within the condensed consolidated statements of operations and comprehensive loss was as follows (in thousands):
For the three months ended June 30,For the six months ended June 30,

2024202320242023
Stock options$1,192 $1,710 $2,422 $3,433 
Restricted stock units2,012 3,969 4,463 7,637 
Employee stock purchase plan and other2 75 83 75 
$3,206 $5,754 $6,968 $11,145 
Schedule of Stock-Based Compensation Expense by Classification
Stock-based compensation expense by classification included within the condensed consolidated statements of operations and comprehensive loss was as follows (in thousands): 
For the three months ended June 30,For the six months ended June 30,
2024202320242023
Cost of product revenue289 (10)780 93 
Selling, general and administrative1,798 2,681 4,133 5,042 
Research and development1,119 3,083 2,055 6,010 
$3,206 $5,754 $6,968 $11,145 
Summary of Stock Option Activity Under Plan
The following table summarizes the stock option activity under the Company’s equity award plans excluding awards held by employees of 2seventy bio:
Shares
(in thousands)
Weighted-
average
exercise price
per share
Outstanding at December 31, 20234,227 $14.16 
Granted2,672 $1.54 
Exercised— $— 
Canceled, forfeited, or expired(600)$10.86 
Outstanding at June 30, 20246,299 $9.13 
Exercisable at June 30, 20242,196 $19.60 
Vested and expected to vest at June 30, 20246,299 $9.13 
Summary of Restricted Common Stock Awards
The following table summarizes the restricted stock unit activity under the Company’s equity award plans excluding awards held by employees of 2seventy bio:
Shares
(in thousands)		Weighted-
average
grant date
fair value
Unvested at December 31, 20234,207 $6.08 
Granted2,337 $1.54 
Vested(970)$6.76 
Forfeited(577)$4.09 
Unvested at June 30, 20244,997 $4.05