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Stock-based compensation (Tables)
 3 Months Ended
Mar. 31, 2024
Share-Based Payment Arrangement [Abstract]  
Summary of Stock-Based Compensation Expense by Award Type Stock-based compensation expense recognized by award type is included within the condensed consolidated statements of operations and comprehensive loss was as follows (in thousands):
For the three months ended March 31,

20242023
Stock options$1,230 $1,723 
Restricted stock units2,451 3,668 
Employee stock purchase plan and other80 — 
$3,761 $5,391 
Schedule of Stock-Based Compensation Expense by Classification
Stock-based compensation expense by classification included within the condensed consolidated statements of operations and comprehensive loss was as follows (in thousands): 
For the three months ended March 31,
20242023
Cost of product revenue491 103 
Selling, general and administrative2,335 2,361 
Research and development935 2,927 
$3,761 $5,391 
Summary of Stock Option Activity Under Plan
The following table summarizes the stock option activity under the Company’s equity award plans excluding awards held by employees of 2seventy bio:
Shares
(in thousands)
Weighted-
average
exercise price
per share
Outstanding at December 31, 20234,227 $14.16 
Granted2,572 $1.56 
Exercised— $— 
Canceled, forfeited, or expired(229)$16.55 
Outstanding at March 31, 20246,570 $9.16 
Exercisable at March 31, 20241,871 $22.75 
Vested and expected to vest at March 31, 20246,570 $9.16 
Summary of Restricted Common Stock Awards
The following table summarizes the restricted stock unit activity under the Company’s equity award plans excluding awards held by employees of 2seventy bio:
Shares
(in thousands)		Weighted-
average
grant date
fair value
Unvested at December 31, 20234,207 $6.08 
Granted2,177 $1.56 
Vested(785)$7.14 
Forfeited(205)$4.41 
Unvested at March 31, 20245,394 $4.16