Summary of significant accounting policies and basis of presentation - Estimated Useful Lives of Assets (Detail)	Dec. 31, 2023
Building
Property, Plant and Equipment [Line Items]
Estimated useful lives of assets	40 years
Computer equipment and software
Property, Plant and Equipment [Line Items]
Estimated useful lives of assets	3 years
Furniture and fixtures
Property, Plant and Equipment [Line Items]
Estimated useful lives of assets	5 years
Laboratory equipment | Minimum
Property, Plant and Equipment [Line Items]
Estimated useful lives of assets	3 years
Laboratory equipment | Maximum
Property, Plant and Equipment [Line Items]
Estimated useful lives of assets	5 years