Property, plant and equipment, net - Summary of Property, Plant and Equipment Net (Detail) - USD ($) $ in Thousands	Sep. 30, 2023	Dec. 31, 2022
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 27,054	$ 31,294
Less accumulated depreciation and amortization	(17,082)	(21,932)
Property, plant and equipment, net	9,972	9,362
Laboratory equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	18,591	25,092
Computer equipment and software
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	2,267	1,854
Office equipment
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	4,646	4,348
Leasehold improvements
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	1,140	0
Construction-in-progress
Property, Plant and Equipment [Line Items]
Total property, plant and equipment	$ 410	$ 0