Condensed Consolidated Statements of Operations and Comprehensive Loss (unaudited) - USD ($) shares in Thousands, $ in Thousands	3 Months Ended		9 Months Ended
	Sep. 30, 2022	Sep. 30, 2021	Sep. 30, 2022	Sep. 30, 2021
Revenue:
Total revenues	$ 71	$ 1,019	$ 3,534	$ 2,056
Operating expenses:
Research and development	53,149	73,679	194,864	240,561
Selling, general and administrative	33,402	42,229	106,201	156,763
Cost of product revenue	0	19,385	10,056	35,176
Restructuring expenses	(1,699)	20,175	4,940	24,800
Total operating expenses	84,852	155,468	316,061	457,300
Loss from operations	(84,781)	(154,449)	(312,527)	(455,244)
Interest income, net	383	160	663	733
Other (expense) income, net	7,885	1,342	13,061	24,369
Loss before income taxes	(76,513)	(152,947)	(298,803)	(430,142)
Income tax (expense) benefit	(7)	113	(7)	(169)
Net loss from continuing operations	(76,520)	(152,834)	(298,810)	(430,311)
Net loss from discontinued operations	0	(63,982)	0	(234,015)
Net loss	$ (76,520)	$ (216,816)	$ (298,810)	$ (664,326)
Net loss per share from continuing operations - basic (in dollars per share)	$ (0.94)	$ (2.23)	$ (3.91)	$ (6.36)
Net loss per share from continuing operations - diluted (in dollars per share)	(0.94)	(2.23)	(3.91)	(6.36)
Net loss per share from discontinued operations - basic (in dollars per share)	0	(0.93)	0	(3.46)
Net loss per share from discontinued operations - diluted (in dollars per share)	0	(0.93)	0	(3.46)
Net loss per share - basic (in dollars per share)	(0.94)	(3.16)	(3.91)	(9.81)
Net loss per share - diluted (in dollars per share)	$ (0.94)	$ (3.16)	$ (3.91)	$ (9.81)
Weighted-average number of common shares used in computing net loss per share - basic (in shares)	81,543	68,621	76,361	67,701
Weighted-average number of common shares used in computing net loss per share - diluted (in shares)	81,543	68,621	76,361	67,701
Other comprehensive (loss) income:
Other Comprehensive Income (Loss), Net of Tax, Portion Attributable to Parent	$ (214)	$ (129)	$ (1,719)	$ (401)
Comprehensive loss	(76,734)	(216,945)	(300,529)	(664,727)
Product revenue
Revenue:
Revenue	0	768	2,739	1,492
Other revenue
Revenue:
Revenue	$ 71	$ 251	$ 795	$ 564