Discontinued operations (Tables)

9 Months Ended

Sep. 30, 2022

Discontinued Operations and Disposal Groups [Abstract]

Summary of Revenues , Expenses, Non-cash Items and Capital Expenditures for Discontinued Operations

The following table summarizes revenue and expenses of the discontinued operations for the three and nine months ended September 30, 2021 (in thousands):

	Three months ended September 30, 2021		Nine months ended September 30, 2021
Revenue:
Service revenue	$	6,312	$	17,544
Collaborative arrangement revenue	14,738		17,927
Royalty and other revenue	609		5,417
Total revenues	21,659		40,888
Operating expenses:
Research and development	57,748		189,053
Selling, general and administrative	26,048		72,945
Share of collaboration loss	—		10,071
Cost of royalty and other revenue	320		2,111
Change in fair value of contingent consideration	48		464
Total operating expenses	84,164		274,644
Loss from operations	(62,505)		(233,756)
Interest income, net	159		735
Other income, net	(1,636)		(994)
Loss before income taxes	(63,982)		(234,015)
Income tax benefit (expense)	—		—
Net loss	$	(63,982)	$	(234,015)

The following table summarizes the significant non-cash items and capital expenditures of the discontinued operations that are included in the condensed consolidated statements of cash flows for the nine months ended September 30, 2021 (in thousands):

	Nine months ended September 30, 2021
Operating activities:
Change in fair value of contingent consideration	$	464
Depreciation and amortization	12,967
Stock-based compensation expense	26,189
Loss on fixed asset disposal	254
Loss on sale of manufacturing facility	1,986
Investing activities:
Purchase of property, plant and equipment	$	(10,579)
Proceeds from sale of manufacturing facility	110,300
Purchase of intangible assets	(8,000)
Supplemental cash flow disclosures:
Purchases of property, plant and equipment included in accounts payable and accrued expenses	$	321